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Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro
Abstract
Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive immunization can be a practical alternative to conventional vaccination in order to prevent the disease. In this report the production of chicken egg yolk IgY and its ability to neutralize BRSV in vitro were assessed. Purified IgY against
[ver mas...]
Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive immunization can be a practical alternative to conventional vaccination in order to prevent the disease. In this report the production of chicken egg yolk IgY and its ability to neutralize BRSV in vitro were assessed. Purified IgY against BRSV specifically recognized BRSV in a dot blot assay and was able to neutralize the virus in a viral neutralization assay. These results demonstrate the potential use of IgY as a prophylactic treatment against RSV infection.
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Descripción
5th Vaccine and ISV Annual Global Congress, Seattle, United States of America, 2nd to 4th October 2011
Fuente
Procedia in vaccinology 6 : 33-38. (2012)
Date
2012
Editorial
Elsevier
ISSN
1877-282X
Formato
pdf
Tipo de documento
artículo
Derechos de acceso
Abierto

Metadata
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