Recent Submissions

  • Whole-genome analysis of natural interspecific recombinant between bovine alphaherpesviruses 1 and 5 

    Romera, Sonia Alejandra; Perez, Ruben; Marandino, Ana; Tau, Rocio Lucia; Campos, Fabricio; Roehe, Paulo Michel; Thiry, Etienne; Maidana, Silvina Soledad (Elsevier, 2022-02)
    Bovine alphaherpesviruses 1 and 5 (BoHV-1 and BoHV-5) are closely related viruses that co-circulate in South America and recombine in the field. The complete genomes of three natural gB gene recombinant viruses between ...
  • Detection, risk factors and molecular diversity of norovirus GIII in cattle in Uruguay 

    Castells, Matias; Caffarena, Rubén Darío; Casaux, María Laura; Schild, Carlos; Castells, Felipe; Castells, Daniel; Victoria, Matías; Riet‑Correa, Franklin; Giannitti, Federico; Parreño, Viviana; Colina, Rodney (Elsevier, 2020-12)
    Uruguay is a leading exporter of bovine meat and dairy products, and cattle production is one of the principal economic backbones in this country. A main clinical problem faced by livestock farmers is neonatal calf diarrhea ...
  • TLR activation, immune response and viral protection elicited in cattle by a commercial vaccine against Bovine Herpesvirus-1 

    Kornuta, Claudia Alejandra; Cheuquepan Valenzuel, Felipe Andres; Bidart, , Juan Esteban; Soria, Ivana; Gammella, Mariela; Quattrocchi, Valeria; Hecker, Yanina; Moore, Prando Dadin; Romera, Sonia Alejandra; Marin, Maia Solange; Zamorano, Patricia Ines; Langellotti, Cecilia Ana (Elsevier, 2022-01)
    The innate and acquired immune response induced by a commercial inactivated vaccine against Bovine Herpesvirus-1 (BoHV-1) and protection conferred against the virus were analyzed in cattle. Vaccination induced high levels ...
  • Equine Coital Exanthema: new insights on the knowledge and leading perspectives for treatment and prevention 

    Vissani, Aldana; Damiani, Armando Mario; Barrandeguy, Maria Edith (MDPI, 2021-08)
    Equine coital exanthema (ECE) is a highly contagious, venereally-transmitted mucocutaneous disease, characterized by the formation of papules, vesicles, pustules and ulcers on the external genital organs of mares and ...
  • Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus 

    Dalvie, Neil C.; Brady, Joseph R.; Crowell, Laura E.; Tracey, Mary Kate; Biedermann, Andrew M.; Kaur, Kawaljit; Hickey, John M.; Kristensen II, D. Lee; Bonnyman, Alexandra D.; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Bok, Marina; Vega, Celina Guadalupe; Mukhopadhyay, Tarit K.; Joshi, Sangeeta B.; Volkin, David B.; Parreño, Gladys; Love, Kerry R.; Love, J. Christopher (BMC, 2021-05)
    Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ...
  • FMD empty capsids combined with the immunostant particle adjuvant -ISPA or ISA206 induce protective immunity against foot and mouth disease virus 

    Bidart, Juan Esteban; Mignaqui, Ana Clara; Kornuta, Claudia Alejandra; Lupi, Giuliana; Gammella, Mariela; Soria, Ivana; Galarza, Roxana Ivon; Ferella, Alejandra; Cardillo, Sabrina Beatriz; Langellotti, Cecilia Ana; Quattrocchi, Valeria; Durocher, Yves; Wigdorovitz, Andres; Marcipar, Ivan; Zamorano, Patricia Ines (Elsevier, 2021-05)
    Foot and Mouth Disease Virus (FMDV) causes economy losses and is controlled by vaccination in many countries. Vaccine formulations based on empty capsids or Virus-Like Particles (VLPs) have the advantage of avoiding the ...
  • Preservation of protective capacity of hyperimmune anti-Stx2 bovine colostrum against enterohemorrhagic Escherichia coli O157:H7 pathogenicity after pasteurization and spray-drying processes 

    Garimano, Nicolás; Diaz Vergara, Ladislao Iván; Kim, A. D.; Badin, Emiliano Emanuel; Sodero, Sonia; Bernal, Alan Mauro; Gonzalez, Diego; Amaral, María Marta; Lespinard, Alejandro R.; Porporatto, Carina; Montenegro, Mariana A.; Palermo, Marina Sandra; Larzabal, Mariano; Cataldi, Angel Adrian; Ibarra, Cristina Adriana; Sacerdoti, Flavia (Elsevier, 2021-05)
    Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a major etiologic agent that causes bloody diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS). Shiga toxin (Stx) is the main virulence factor of EHEC ...
  • Evidence of porcine circovirus type 2 and co-infection with ungulate protoparvovirus 1 (porcine parvovirus) in mummies and stillborn piglets in subclinically infected farm 

    Serena, Maria Soledad; Dibarbora, Marina; Olivera, Valeria Soledad; Metz, German Ernesto; Aspitia, Carolina Gabriela; Pereda, Ariel Julian; Echeverria, Maria Gabriela; Cappuccio, Javier Alejandro (Elsevier, 2021-04)
    Porcine circovirus type 2 (PCV2) and protoparvovirus 1 (PPV) were detected as single infection (6/131) and (11/131) respectively, or co-infection (6/131) in fetuses and stillborn piglets from normal deliveries in a farm ...
  • Towards inclusive funding practices for early career researchers 

    de Winde, Charlotte M.; Sarabipour, Sarvenaz; Carignano, Hugo Adrian; Davla, Sejal; Eccles, David; Hainer, Sarah J.; Haidar, Mansour; Ilangovan, Vinodh; Jadavji, Nafisa M.; Kritsiligkou, Paraskevi; Lee, Tai-Ying; Ólafsdóttir, H. Freyja (2021-03)
    Securing research funding is a challenge faced by most scientists in academic institutions worldwide. Funding success rates for all career stages are low, but the burden falls most heavily on early career researchers (ECRs). ...
  • Balance between retroviral latency and transcription : based on HIV model 

    Pluta, Aneta; Jaworski, Juan Pablo; Cortés-Rubio, César N. (MDPI, 2021-01)
    The representative of the Lentivirus genus is the human immunodeficiency virus type 1 (HIV-1), the causative agent of acquired immunodeficiency syndrome (AIDS). To date, there is no cure for AIDS because of the existence ...
  • Evaluation of a lyophilized CRISPR-Cas12 assay for a sensitive, specific, and rapid detection of SARS-CoV-2 

    Curti, Lucía Ana; Primost, Ivana; Valla, Sofia; Ibañez Alegre, Daiana; Olguin Perglione, Cecilia; Repizo, Guillermo Daniel; Lara, Julia; Parcerisa, Ivana; Palacios, Antonela; Llases, María Eugenia; Rinflerch, Adriana; Barrios, Melanie; Pereyra Bonnet, Federico; Gimenez, Carla Alejandra; Marcone, Débora Natalia (MDPI, 2021-03)
    We evaluated a lyophilized CRISPR-Cas12 assay for SARS-CoV-2 detection (Lyo-CRISPR SARS-CoV-2 kit) based on reverse transcription, isothermal amplification, and CRISPR-Cas12 reaction. From a total of 210 RNA samples extracted ...
  • An improved DNA vaccine against bovine herpesvirus-1 using CD40L and a chemical adjuvant induces specific cytotoxicity in mici 

    Langellotti, Cecilia Ana; Gammella, Mariela; Soria, Ivana; Bellusci, Carolina; Quattrocchi, Valeria; Vermeulen, Elba Monica; Mongini, Claudia; Zamorano, Patricia Ines (Mary Ann Liebert, 2021-03)
    Bovine herpesvirus-1 (BoHV-1) uses many mechanisms to elude the immune system; one of them is spreading intracellularly, even in the presence of specific antiviral antibodies. Cytotoxic T lymphocytes (CTLs) are necessary ...
  • Expression-based analysis of genes related to single nucleotide polymorphism hits associated with bovine leukemia virus proviral load in Argentinean dairy cattle 

    Petersen, Marcos Iván; Carignano, Hugo Adrian; Suarez Archilla, Guillermo; Caffaro, María Eugenia; Alvarez, Irene; Miretti, Marcos Mateo; Trono, Karina Gabriela (Elsevier, 2021-02)
    In dairy cattle infected with bovine leukemia virus (BLV), the proviral load (PVL) level is directly related to the viral transmission from infected animals to their healthy herdmates. Two contrasting phenotypic groups can ...
  • A new cage-like particle adjuvant enhances protection of foot-and-mouth disease vaccine 

    Bidart, Juan Esteban; Kornuta, Claudia Alejandra; Gammella, Mariela; Gnazzo, Victoria; Soria, Ivana; Langellotti, Cecilia Ana; Mongini, Claudia; Galarza, Roxana Ivon; Calvinho, Luis Fernando; Lupi, Giuliana; Quattrocchi, Valeria; Marcipar, Ivan; Zamorano, Patricia Ines (Frontiers Media, 2020-07)
    Foot-and-Mouth Disease (FMD) is an acute viral disease that causes important economy losses. Vaccines with new low-cost adjuvants that stimulate protective immune responses are needed and can be assayed in a mouse model ...
  • Bovine dendritic cell activation, T cell proliferation and antibody responses to foot-and-mouth disease, is similar with inactivated virus and virus like particles 

    Quattrocchi, Valeria; Bidart, Juan Esteban; Mignaqui, Ana Clara; Ruiz, Vanesa; Ferella, Alejandra; Langellotti, Cecilia Ana; Gammella, Mariela; Ferraris, Sergio; Carrillo, Jorge Ernesto; Wigdorovitz, Andres; Durocher, Yves; Cardillo, Sabrina Beatriz; Charleston, Bryan; Zamorano, Patricia Ines (Frontiers Media, 2020-09)
    Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals that causes severe economic losses in the livestock industry. Currently available vaccines are based on the inactivated FMD virus (FMDV). ...
  • A plasmid encoding the extracellular domain of CD40 ligand and MontanideTM GEL01 as adjuvants enhance the immunogenicity and the protection induced by a DNA vaccine against BoHV-1 

    Kornuta, Claudia Alejandra; Langellotti, Cecilia Ana; Bidart, , Juan Esteban; Soria, Ivana; Quattrocchi, Valeria; Gammella, Mariela; Cheuquepan Valenzuela, Felipe; Mignaqui, Ana Clara; Ferraris, Sergio; Charleston, Bryan; Hecker, Yanina; Moore, Prando Dadin; Zamorano, Patricia Ines (Elsevier, 2021-02)
    DNA vaccines are capable of inducing humoral and cellular immunity, and are important to control bovine herpesvirus 1 (BoHV-1), an agent of the bovine respiratory disease complex. In previous work, a DNA plasmid that encodes ...
  • Analysis of irradiated Argentinean fetal bovine serum for adventitious agents 

    Pecora, Andrea; Perez Lopez, Jorgelina; Jordan, Maximiliano Jesus; Franco, Lautaro Nahuel; Politzki, Romina Paula; Ruiz, Vanesa; Alvarez, Irene (Sage Publications, 2020-11)
    Fetal bovine serum (FBS) used in cell culture may be contaminated with adventitious agents, which can affect the production of biologicals and the results of clinical laboratory tests. We carried out a retrospective study ...
  • Editorial: Emerging swine viruses 

    Perfumo, Carlos Juan; Pereda, Ariel Julian; Jongkaewwattana, Anan; Chen, Zhenhai; Perez, Daniel Roberto; Ma, Jingyun (Frontiers Media, 2020-03)
    Over the last 30 years, diseases caused by emerging swine viruses (ESV) have acquired great relevance, more than in other species. Diseases caused by porcine reproductive and respiratory syndrome virus (PRRSv), high ...
  • In-vivo activity of IFN-λ and IFN-α against bovine-viral-diarrhea virus in a mouse model 

    Quintana, Maria Eugenia; Barone, Lucas Jose; Trotta, Myrian Vanesa; Turco, Cecilia Soledad; Mansilla, Florencia Celeste; Capozzo, Alejandra; Cardoso, Nancy (Frontiers Media, 2020-02)
    Bovine-viral-diarrhea virus (BVDV) can cause significant economic losses in livestock. The disease is controlled with vaccination and bovines are susceptible until vaccine immunity develops and may remain vulnerable if a ...
  • MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1 

    Kornuta, Claudia Alejandra; Bidart, , Juan Esteban; Soria, Ivana; Gammella, Mariela; Quattrocchi, Valeria; Pappalardo, Juan Sebastián; Salmaso, Stefano; Torchilin, Vladimir P.; Cheuquepan Valenzuel, Felipe Andres; Hecker, Yanina; Moore, Dadin P.; Zamorano, Patricia Ines; Langellotti, Cecilia Ana (Wiley, 2020-07)
    New technologies in the field of vaccinology arise as a necessity for the treatment and control of many diseases. Whole virus inactivated vaccines and modified live virus ones used against Bovine Herpesvirus‐1 (BoHV‐1) ...

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