Instituto de Virología
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Molecular characterization of pestiviruses in fetal bovine sera originating from Argentina: evidence of circulation of HoBi-like viruses
(Frontiers Media, 2019-10)Serological evidence suggests that HoBi-like viruses, an emerging species within the Pestivirus genus of the Flaviviridae family, are in circulation in Argentina. While HoBi-like viruses were first isolated from Brazilian ... -
A direct high-throughput in Cell-ELISA for measuring infectivity of cytopathic and non-cytopathic bovine viral diarrhoea virus strains applied to the assessment of antiviral activity
(Elsevier, 2018-07-19)Low-cost high-throughput methods applicable to any virus strain are required for screening antiviral compounds against multiple field strains. Colorimetric cell-viability assays are used for this purpose as long as the ... -
Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries
(Springer, 2019-11)Bovine coronavirus (BCoV) is a recognized cause of severe neonatal calf diarrhea, with a negative impact on animal welfare, leading to economic losses to the livestock industry. Cattle production is one of the most important ... -
Estudio del efecto del uso de anticuerpos específicos contra el virus de la leucosis bovina como suplemento dietario en terneros
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires., 2018)En este trabajo se estudió el efecto del uso de anticuerpos de yema de huevo (IgY) anti BLV específicos como suplemento en la leche de consumo de terneros durante todo el período de cría, monitoreando a los animales desde ... -
Stable infection of a bovine mammary epithelial cell line (MAC-T) with bovine leukemia virus (BLV)
(Elsevier, 2018)Bovine leukemia virus (BLV) is a retrovirus that affects cattle causing a lymphoproliferative disease. BLV infection has been associated with misbalance of the immune response causing a higher incidence of other infections. ... -
Síndrome diarreico en potrillos, diagnóstico y caracterización de los agentes virales involucrados
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2017-08)Las diarreas neonatales representan uno de los síndromes clínicos más relevantes y frecuentes en potrillos menores de 6 meses de edad. Rotavirus grupo A (RVA) es el principal agente viral asociado a diarreas en potrillos, ... -
Vacuna “marcadora” contra el HVB-1
(Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2011-04)Investigadores del INTA trabajaron en el desarrollo de un producto que previene una enfermedad que provoca importantes pérdidas económicas y que permite diferenciar entre animales vacunados e infectados. -
Immune cells transferred by colostrum do not influence the immune responses to foot-and-mouth disease primary vaccination
(Elsevier, 2019-09)Little is known about the influence of maternal antibodies and immune cells transferred through colostrum on the immune responses of calves to the currently used foot-and-mouth disease (FMD) vaccines. Here we evaluated the ... -
Immune mediators of pathology in neurobrucellosis: from blood to central nervous system
(Elsevier, 2019-07)Neurobrucellosis, which is the most morbid form of brucellosis disease, presents with inflammatory signs and symptoms. Recent experimental evidence clearly indicates that deregulation of astrocytes and microglia caused by ... -
Bovine leukemia virus infection in neonatal calves. Risk factors and control measures
(Frontiers Media, 2018-10)Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (EBL). Although efficient eradication programs have been successfully implemented in most European countries and Oceania, BLV infection rates ... -
Detection of bovine leukemia virus RNA in blood samples of naturally infected dairy cattle
(MDPI, 2019-09)The viral expression in vivo, in bovine leukemia virus (BLV)-infected cattle, is considered to be restricted to extremely low levels, and the mitosis of infected B lymphocytes is regarded as the main mode of virus persistence ... -
Estimating the protection afforded by foot-and-mouth disease vaccines in the laboratory
(Elsevier, 2019-09)Foot-and-mouth disease (FMD) vaccines must be carefully selected and their application closely monitored to optimise their effectiveness. This review covers serological techniques for FMD vaccine quality control, including ... -
Caracterización del virus de influenza en cerdos en Argentina
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2016)La infección por Influenza A virus (IAV) es considerada una de las principales causas de enfermedad respiratoria en cerdos. Además, su carácter zoonótico representa un riesgo para la salud pública. En Argentina, si bien ... -
Prevención y tratamiento de Rotavirus A mediante nanoanticuerpos VHH anti-VP6
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2017-06)La diarrea asociada a Rotavirus A (RVA) representa una de las principales causas de mortalidad infantil a nivel mundial. Si bien la vacunación masiva contra RVA ha logrado disminuir significativamente las muertes causadas ... -
Spontaneous virus reactivation in cattle chronically infected with bovine leukemia virus
(BioMed Central, 2019)Background: The absence of virus expression during the chronic stage of bovine leukemia virus (BLV) infection and its reactivation upon ex vivo culture has become a long-lived Dogma. During the chronic stage of BLV ... -
Worldwide evolution of equine RVA: four voices, one story
(2018-09)In this work, we used a Bayesian approach, together with all the information that was available in databases, to study the evolution of equine RVA. -
Rotavirus species tropism: new insights on P-type classification
(2018-11)To study the aminoacid regions that are involved in the VP8 pocket in order to find a molecular fingerprint for the virus species tropism. -
Recent advances in BLV research
(MDPI, 2015-11)Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and ... -
Advances in novel vaccines for foot and mouth disease: focus on recombinant empty capsids
(Taylor & Francis, 2019-05)Foot and mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals, which causes severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ... -
Development and evaluation of a one-step multiplex real-time TaqMan® RT-qPCR assay for the detection and genotyping of equine G3 and G14 rotaviruses in fecal samples
(BMC, 2019-04)Background: Equine rotavirus A (ERVA) is the leading cause of diarrhea in neonatal foals and has a negative impact on equine breeding enterprises worldwide. Among ERVA strains infecting foals, the genotypes G3P[12] and ...