Artículos científicos
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Detection and characterization of Deformed Wing Virus (DWV) in apiaries with stationary and migratory management in the province of Entre Ríos, Argentina
(Springer Nature, 2024-07)In Argentina, migratory activity in search of floral diversity has become a common approach to maximizing honey production. The Entre Ríos province possesses a floral diversity that allows beekeepers to perform migratory ... -
First report of Equine Parvovirus-Hepatitis (EqPV-H) in Argentina
(Elsevier, 2024-07)The novel Equine Parvovirus-Hepatitis (EqPV-H) was first identified in the serum and liver of a horse that died of equine serum hepatitis, also known as Theiler's disease. Several reports in recent years strongly suggest ... -
Integrated hepatitis e virus monitoring in central Argentina : a six-year analysis of clinical surveillance and wastewater-based epidemiology
(Elsevier, 2024-09)Wastewater-based epidemiology (WBE) has gained prominence worldwide as a powerful tool in public health. This study aimed to monitor the circulation of Hepatitis E Virus (HEV) from wastewater samples collected during a ... -
Fasciola hepatica infection modifies IgG1 specific immune response to foot-and-mouth disease virus induced by vaccination
(Elsevier, 2024-01)Fasciola hepatica, a worldwide distributed helminth, has a robust immunoregulatory effect in the host, increasing the susceptibility to secondary infections. Foot and mouth disease (FMD) is a highly contagious acute vesicular ... -
SARS-CoV-2 specific nanobodies neutralize different variants of concern and reduce virus load in the brain of h-ACE2 transgenic mice
(MDPI, 2024-02)Since the beginning of the COVID-19 pandemic, there has been a significant need to develop antivirals and vaccines to combat the disease. In this work, we developed llama-derived nanobodies (Nbs) directed against the ... -
Serological responses of Guinea pigs and heifers to eight different BoAHV-1 vaccine formulations
(MDPI, 2024-06)Bovine alphaherpesvirus 1 (BoAHV-1) infection affects the production and reproductive performance of dairy and beef livestock, resulting in considerable economic losses. In addition to biosecurity measures, vaccination ... -
Equine rotavirus a under the one health lens : potential impacts on public health
(MDPI, 2024-01)Group A rotaviruses are a well-known cause of viral gastroenteritis in infants and children, as well as in many mammalian species and birds, affecting them at a young age. This group of viruses has a double-stranded, ... -
Complete genome sequence of deformed wing virus and black queen cell virus isolated from honeybees (Apis mellifera) in Argentina
(American Society for Microbiology, 2024-03)We report the complete genome sequence of deformed wing virus and black queen cell virus isolated from Argentinean’s honeybees. These sequence data will be valuable for future research on the viral variants present in the ... -
A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations containing alum increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection in mice
(Frontiers Media, 2022-02)In this work, we evaluated recombinant receptor binding domain (RBD)-based vaccine formulation prototypes with potential for further clinical development. We assessed different formulations containing RBD plus alum, AddaS03, ... -
Longitudinal follow-up of the immunity to SARS-CoV-2 in health care workers in Argentina : persistence of humoral response and neutralizing capacity after Sputnik V vaccination
(American Society for Microbiology, 2023-06)SARS-CoV-2 vaccine protection has encountered waning of immune response and breakthrough infections. The hybrid immune response generated by the combination of vaccination and infection was shown to offer higher and broader ... -
Molecular characterization of group A rotavirus strains detected in alpacas (Vicugna pacos) from Peru
(Microbiology Society, 2021-04)The alpaca is a very important social and economic resource for the production of fibre and meat for Andean communities. Peru is the main producer of alpacas. Group A rotavirus (RVA) has been sporadically detected in ... -
Impact of genetic ancestry on the distribution of interferon-λ4 RS12979860 polymorphism in a global population of Buenos Aires, Argentina = Impacto de la ancestría genética en la distribución del polimorfismo de interferón-λ4 RS12979860 en una población global de Buenos Aires, Argentina
(Sociedad Argentina de Genética, 2022-12)Human interferon-λ4 is a cytokine involved in early stages of antiviral responses. Strikingly, some allelic variants with diminished antiviral activity reduce the susceptibility to viral infections, thus they would have ... -
The MVA vector expressing the F protein of bovine respiratory syncytial virus is immunogenic in systemic and mucosal immunization routes = El vector viral MVA que expresa la proteína F del virus respiratorio sincicial bovino es inmunogénico al administrarse por vía sistémica y por mucosas
(Elsevier, 2023-12)Bovine respiratory syncytial virus (BRSV) affects both beef and dairy cattle, reaching morbidity and mortality rates of 60---80% and 20%, respectively. The aim of this study was to obtain a recombinant MVA expressing the ... -
A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity
(Nature Publishing Group, 2023-10)Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus ... -
Serological evidence of SARS-CoV-2 infection in pets naturally exposed during the COVID-19 outbreak in Argentina
(Elsevier, 2022-12)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), has rapidly spread worldwide. The monitoring of animals has shown that certain species may be ... -
Probiotic as adjuvant significantly improves protection of the Lanzhou trivalent rotavirus vaccine against heterologous challenge in a gnotobiotic pig model of human rotavirus infection and disease
(MDPI, 2022-09)This preclinical study in the gnotobiotic (Gn) pig model of human rotavirus (HRV) infection and disease evaluates the effect of probiotic Lactobacillus rhamnosus GG (LGG) as a mucosal adjuvant on the immunogenicity and ... -
Origin of new lineages by recombination and mutation in avian infectious bronchitis virus from South America
(MDPI, 2022-10)The gammacoronavirus avian infectious bronchitis virus (IBV) is a highly contagious respiratory pathogen of primary economic importance to the global poultry industry. Two IBV lineages (GI-11 and GI-16) have been widely ... -
Feasibility of polyclonal avian immunoglobulins (IgY) as prophylaxis against human norovirus infection
(MDPI, 2022-11)Background: Human norovirus (HuNoV) is the leading viral cause of diarrhea, with GII.4 as the predominant genotype of HuNoV outbreaks globally. However, new genogroup variants emerge periodically, complicating the development ... -
A new gnotobiotic pig model of P[6] human rotavirus infection and disease for preclinical evaluation of rotavirus vaccines
(MDPI, 2022-12)Human rotavirus (HRV) is a leading cause of gastroenteritis in children under 5 years of age. Licensed vaccines containing G1P[8] and G1-4P[8] strains are less efficacious against newly emerging P[6] strains, indicating ... -
Pandemic (H1N1) 2009 outbreak on pig farm, Argentina
(Centers for Disease Control and Prevention, 2010-02)In June–July 2009, an outbreak of pandemic (H1N1) 2009 infection occurred on a pig farm in Argentina. Molecular analysis indicated that the virus was genetically related to the pandemic (H1N1) 2009 influenza virus strain. ...