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The structural analyses revealed that the aa substitutions in VP7 are in the antigenic sites and in the VP7:VP6 interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving antigenic and VP7:VP6 interaction sites. Interestingly, the structural analyses of VP8* showed a few aa differences in the antigenic sites and, all equine P[12] shown the same conserved aa sequence in VP8* pocket, only observed in P[12] [ver mas...]
dc.contributor.authorMiño, Samuel
dc.contributor.authorParreño, Viviana
dc.contributor.authorBarrandeguy, Maria Edith
dc.date.accessioned2017-08-23T13:39:08Z
dc.date.available2017-08-23T13:39:08Z
dc.date.issued2016
dc.identifier.issn0737-0806
dc.identifier.otherhttp://dx.doi.org/10.1016/j.jevs.2016.02.055
dc.identifier.urihttp://hdl.handle.net/20.500.12123/1015
dc.identifier.urihttp://www.j-evs.com/article/S0737-0806(16)00086-1/pdf
dc.description.abstractThe structural analyses revealed that the aa substitutions in VP7 are in the antigenic sites and in the VP7:VP6 interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving antigenic and VP7:VP6 interaction sites. Interestingly, the structural analyses of VP8* showed a few aa differences in the antigenic sites and, all equine P[12] shown the same conserved aa sequence in VP8* pocket, only observed in P[12] genotype. Our study suggest the existence of geographically related equine RVA lineages and, describe the aa configuration of the VP8* pocket.
dc.formatapplication/pdf
dc.language.isoeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceJournal of equine veterinary science 39 : S23eS25
dc.subjectAnimal Diseaseseng
dc.subjectEnfermedades de los Animales
dc.subjectRotavirus
dc.subjectCaballos
dc.subjectHorseseng
dc.subjectGenética
dc.subjectGeneticseng
dc.titlePhylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.rights.licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.description.origenInst.de Virología
dc.gic152382
dc.description.filFil: Miño, Samuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
dc.description.filFil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina
dc.description.filFil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; Argentina
dc.subtypecientifico


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