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Mostrando ítems 1-6 de 6

    • Babesia bovis AMA-1, MSA-2c and RAP-1 contain conserved B and T-cell epitopes, which generate neutralizing antibodies and a long-lasting Th1 immune response in vaccinated cattle 

      Hidalgo-Ruiz, Mario; Mejia-López, Susana; Pérez-Serrano, Rosa M.; Zaldívar-Lelo de Larrea, Guadalupe; Ganzinelli, Sabrina Belen; Florin-Christensen, Monica; Suarez, Carlos Esteban; Hernández-Ortiz, Rubén; Mercado-Uriostegui, Miguel A.; Rodríguez-Torres, Angelina; Carvajal-Gamez, Bertha I.; Camacho-Nuez, Minerva; Wilkowsky, Silvina Elizabeth; Mosqueda, Juan (Elsevier, 2022-02)
      Vaccines against bovine babesiosis must, ideally, induce a humoral immune response characterized by neutralizing antibodies against conserved epitopes and a cellular Th1 immune response. In Babesia bovis, proteins such as ...

    • Degrade to survive : the intricate world of piroplasmid proteases 

      Florin-Christensen, Mónica; Sojka, Daniel; Ganzinelli, Sabrina Belen; Snebergerová, Pavla; Suarez, Carlos Esteban; Schnittger, Leonhard (Elsevier, 2023-07)
      Piroplasmids of the genera Babesia, Theileria, and Cytauxzoon are tick-transmitted parasites with a high impact on animals and humans. They have complex life cycles in their definitive arthropod and intermediate vertebrate ...

    • N-Glycosylation in piroplasmids : Diversity within simplicity 

      Florin-Christensen, Mónica; Rodriguez, Anabel Elisa; Suarez, Carlos Esteban; Ueti, Massaro W.; Delgado, Fernando Oscar; Echaide, Ignacio Eduardo; Schnittger, Leonhard (MDPI, 2021-01)
      N-glycosylation has remained mostly unexplored in Piroplasmida, an order of tick-transmitted pathogens of veterinary and medical relevance. Analysis of 11 piroplasmid genomes revealed three distinct scenarios regarding ...

    • The glycosylphosphatidylinositol-anchored protein repertoire of Babesia bovis and its significance for erythrocyte invasion 

      Rodriguez, Anabel Elisa; Florin-Christensen, Mónica; Flores, Daniela; Echaide, Ignacio Eduardo; Suarez, Carlos Esteban; Schnittger, Leonhard (2014-04)
      Glycosylphosphatidylinositol-anchored proteins are abundant on the surface of pathogenic protozoans and might play an important role for parasite survival. In the present work, the relevance of GPI-anchored proteins for ...

    • Unraveling the complexity of the rhomboid serine protease 4 family of Babesia bovis using bioinformatics and experimental studies 

      Gallenti, Romina Josefina; Hussein, Hala E.; Alzan, Heba F.; Suarez, Carlos Esteban; Ueti, Massaro W.; Asurmendi, Sebastian; Benitez, Daniel Francisco; Araujo, Flabio Ribeiro de; Rolls, Peter; Sibeko, Kgomotso; Schnittger, Leonhard; Florin-Christensen, Mónica (MDPI, 2022-03)
      Babesia bovis, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and subtropical regions around the world. In the apicomplexans Toxoplasma gondii and Plasmodium falciparum, rhomboid serine protease 4 ...

    • Vaccines against bovine babesiosis: where we are now and possible roads ahead 

      Florin-Christensen, Mónica; Suarez, Carlos Esteban; Rodriguez, Anabel Elisa; Flores, Daniela; Schnittger, Leonhard (Cambridge University Press, 2014-10)
      Bovine babesiosis caused by the tick-transmitted haemoprotozoans Babesia bovis, Babesia bigemina and Babesia divergens commonly results in substantial cattle morbidity and mortality in vast world areas. Although existing ...