• A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations containing alum increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection in mice 

      Coria, Lorena M.; Saposnik, Lucas M.; Pueblas Castro, Celeste; Castro, Eliana Florencia; Bruno, Laura A.; Stone, William B.; Pérez, Paula S.; Darriba, Maria Laura; Chemes, Lucia B.; Alcain, Julieta; Mazzitelli, Ignacio; Varese, Augusto; Salvatori, Melina; Auguste, Albert J.; Álvarez, Diego E.; Pasquevich, Karina A.; Cassataro, Juliana (Frontiers Media, 2022-02)
      In this work, we evaluated recombinant receptor binding domain (RBD)-based vaccine formulation prototypes with potential for further clinical development. We assessed different formulations containing RBD plus alum, AddaS03, ...
    • Anthropogenic infection of domestic cats with SARS-CoV-2 alpha variant B.1.1.7 lineage in Buenos Aires 

      Pecora, Andrea; Malacari, Darío Amilcar; Mozgovoj, Marina Valeria; Díaz, María de los Ángeles; Peralta, Andrea Veronica; Cacciabue, Marco Polo Domingo; Puebla, Andrea Fabiana; Carusso, Cristian; Mundo, Silvia Leonor; Gonzalez Lopez Ledesma, María Mora; Gamarnik, Andrea Vanesa; Rinaldi, Osvaldo; Vidal, Osvaldo; Mas, Javier; Dus Santos, Maria Jose (Frontiers Media, 2022-03)
      SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the ...
    • Development of nanobody-displayed whole-cell biosensors for the colorimetric detection of SARS-CoV‑2 

      He, Yawen; Xu, Zhiyuan; Kasputis, Tom; Zhao, Xue; Ibañez, Itati; Pavan, Florencia; Bok, Marina; Malito, Juan Pablo; Parreño, Gladys Viviana; Yuan, Lijuan; Wright, R. Clay; Chen, Juhong (American Chemical Society, 2023-08)
      The accurate and effective detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to preventing the spread of infectious diseases and ensuring human health. Herein, a nanobody-displayed ...
    • Evaluation of a lyophilized CRISPR-Cas12 assay for a sensitive, specific, and rapid detection of SARS-CoV-2 

      Curti, Lucía Ana; Primost, Ivana; Valla, Sofia; Ibañez Alegre, Daiana; Olguin Perglione, Cecilia; Repizo, Guillermo Daniel; Lara, Julia; Parcerisa, Ivana; Palacios, Antonela; Llases, María Eugenia; Rinflerch, Adriana; Barrios, Melanie; Pereyra Bonnet, Federico; Gimenez, Carla Alejandra; Marcone, Débora Natalia (MDPI, 2021-03)
      We evaluated a lyophilized CRISPR-Cas12 assay for SARS-CoV-2 detection (Lyo-CRISPR SARS-CoV-2 kit) based on reverse transcription, isothermal amplification, and CRISPR-Cas12 reaction. From a total of 210 RNA samples extracted ...
    • Longitudinal follow-up of the immunity to SARS-CoV-2 in health care workers in Argentina : persistence of humoral response and neutralizing capacity after Sputnik V vaccination 

      Castro, Eliana Florencia; Acosta, Julián; Moriena, Lucía; Rios Medrano, Mayra; Cibello, Malena Tejerina; Codino, Eduardo; Taborda, Miguel Ángel; Álvarez, Diego E.; Cavatorta, Ana (American Society for Microbiology, 2023-06)
      SARS-CoV-2 vaccine protection has encountered waning of immune response and breakthrough infections. The hybrid immune response generated by the combination of vaccination and infection was shown to offer higher and broader ...
    • Serological evidence of SARS-CoV-2 infection in pets naturally exposed during the COVID-19 outbreak in Argentina 

      Panei, Carlos Javier; Bravi, María Emilia; More, Gastón; de Felice, Lorena Alejandra; Unzaga, Juan Manuel; Salina, Marcos D.; Rivero, Fernando David; Di Lullo, David; Pecoraro, Marcelo; Alvarez, Diego Ezequiel; Castro, Eliana Florencia; Fuentealba, Nadia Analía (Elsevier, 2022-12)
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), has rapidly spread worldwide. The monitoring of animals has shown that certain species may be ...
    • Serological screening of SARS-CoV-2 infection in companion animals of Buenos Aires suburbs 

      Cardoso, Nancy; Rivero, Carla; Castillo, Mariangeles; Mansilla, Florencia Celeste; Pastorino, Florencia; Piccirilli, Guadalupe; Alonso, Laura; Martinez, Gustavo; Di Lullo, David; Bentancor, Leticia Veronica; Capozzo, Alejandra (Frontiers Media, 2023-05)
      The Coronavirus Disease 2019 (COVID-19) is a zoonotic disease caused by the pandemic virus SARS-CoV-2. Domestic and wild animals are susceptible to infection and are potential reservoirs for virus variants. To date, there ...