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Immunization with Neospora caninum profilin induces limited protection and a regulatory T-cell response in mice
(2016)Profilins are actin-binding proteins that regulate the polymerization of actin filaments. In apicomplexan parasites, they are essential for invasion. Profilins also trigger the immune response of the host by activating ... -
Impact of genetic ancestry on the distribution of interferon-λ4 RS12979860 polymorphism in a global population of Buenos Aires, Argentina = Impacto de la ancestría genética en la distribución del polimorfismo de interferón-λ4 RS12979860 en una población global de Buenos Aires, Argentina
(Sociedad Argentina de Genética, 2022-12)Human interferon-λ4 is a cytokine involved in early stages of antiviral responses. Strikingly, some allelic variants with diminished antiviral activity reduce the susceptibility to viral infections, thus they would have ... -
In vitro and in vivo characterization of a typical and a high pathogenic bovine viral diarrhea virus type ii strains
(Frontiers Media, 2018-04)Non-cytopathic (ncp) type 2 bovine viral diarrhea virus (BVDV-2) is widely prevalent in Argentina causing high mortality rates in cattle herds. In this study, we characterized an Argentinean ncp BVDV-2 field isolate (98-124) ... -
In vitro comparison of acyclovir, ganciclovir and cidofovir against equid alphaherpesvirus 3 and evaluation of their efficacy against six field isolates = Comparación in vitro de aciclovir, ganciclovir y cidofovir contra alfa-herpesvirus equino 3 y evaluación de la eficacia de los mismos frente a 6 aislamientos de campo del virus
(Asociación Argentina de Microbiología, 2018)Equid alphaherpesvirus 3 (EHV3) is the etiological agent of equine coital exanthema (ECE), which is a venereal, highly contagious disease, characterized by the formation of papules, vesicles, pustules and ulcers on the ... -
In-vivo activity of IFN-λ and IFN-α against bovine-viral-diarrhea virus in a mouse model
(Frontiers Media, 2020-02)Bovine-viral-diarrhea virus (BVDV) can cause significant economic losses in livestock. The disease is controlled with vaccination and bovines are susceptible until vaccine immunity develops and may remain vulnerable if a ... -
Infectious bursal disease virus assembly causes endoplasmic reticulum stress and lipid droplet accumulation
(MDPI, 2023-06)Gumboro illness is caused by the highly contagious immunosuppressive infectious bursal disease virus (IBDV), which affects the poultry industry globally. We have previously shown that IBDV hijacks the endocytic pathway to ... -
Infectious diseases in donkeys and mules: an overview and update
(Elsevier, 2018-06)The global equine population comprises a total of 114 million equids, which includes an estimate of 44 million donkeys (Equus asinus) and 11 million mules. Donkey populations have gradually expanded throughout the globe, ... -
Influence of antibodies transferred by colostrum in the immune responses of calves to current foot-and-mouth disease vaccines
(2014-11-12)Immunity to currently used oil-adjuvanted inactivated vaccines against foot-and-mouth disease virus (FMDV) has been studied in detail in adult animals; however, the influence of maternally derived antibodies transferred ... -
Influencia de las condiciones de incubación en la detección de anticuerpos contra el Virus de la Leucosis bovina por ELISA = Influence of the incubation conditions on the detection of antibodies to bovine leukemia virus by ELISA
(Sociedad de Medicina Veterinaria, 2013-05)En este trabajo se modificaron las condiciones de incubación del ensayo de ELISAp24 que detecta anticuerpos contra el Virus de la Leucosis bovina, con el propósito de evaluar si se reduce el número de resultados falsos y ... -
Interferon lambda protects cattle against bovine viral diarrhea virus infection
(Elsevier, 2020-12)Interferon lambda (IFN-λ) plays an important role in inducing an antiviral state in mucosal surfaces and has been used as an effective biotherapeutic against several viral diseases. Here we performed a proof of concept ... -
Isolation and molecular characterization of Clostridium perfringens from healthy Merino lambs in Patagonia region, Argentina
(2016)The presence and molecular characterization of Clostridium perfringens in healthy Merino lambs over a six-month period was investigated in this study. Overall, a high prevalence of C. perfringens was detected, even in ... -
Longitudinal follow-up of the immunity to SARS-CoV-2 in health care workers in Argentina : persistence of humoral response and neutralizing capacity after Sputnik V vaccination
(American Society for Microbiology, 2023-06)SARS-CoV-2 vaccine protection has encountered waning of immune response and breakthrough infections. The hybrid immune response generated by the combination of vaccination and infection was shown to offer higher and broader ... -
MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1
(Wiley, 2021-03)New technologies in the field of vaccinology arise as a necessity for the treatment and control of many diseases. Whole virus inactivated vaccines and modified live virus ones used against Bovine Herpesvirus‐1 (BoHV‐1) ... -
Minimally processed crude leaf extracts of Nicotiana benthamiana containing recombinant foot and mouth disease virus-like particles are immunogenic in mice
(Elsevier, 2018-12)Foot-and-mouth disease (FMD) remains one of the most feared viral diseases affecting cloven-hoofed animals, and results in severe economic losses. Currently available vaccines are based on inactivated FMD virus (FMDV). The ... -
Molecular analyses detect natural coinfection of water buffaloes (Bubalus bubalis) with bovine viral diarrhea viruses (BVDV) in serologically negative animals = Detección molecular de coinfección con los virus de la diarrea viral bovina (BVDV) en búfalos de agua (Bubalus bubalis) serológicamente negativos
(Asociación Argentina de Microbiología, 2015)Infection of water buffaloes (Bubalus bubalis) with bovine viral diarrhea viruses (BVDV) has been confirmed in several studies by serological and molecular techniques. In order to determine the presence of persistently ... -
Molecular and antigenic characterization of bovine Coronavirus circulating in Argentinean cattle during 1994–2010
(Elsevier, 2015-12)Bovine coronavirus (BCoV) is an important viral pathogen associated with neonatal calf diarrhea. Our aim was to investigate the incidence of BCoV in diarrhea outbreaks in beef and dairy herds from Argentina during 1994–2010. ... -
Molecular characterization and cluster analysis of field isolates of avian infectious laryngotracheitis virus from Argentina
(2017-12-13)Avian infectious laryngotracheitis (ILT) is a worldwide infectious disease that causes important economic losses in the poultry industry. Although it is known that ILT virus (ILTV) is present in Argentina, there is no ... -
Molecular characterization of equine rotavirus group A detected in Argentinean foals during 2009–2014
(2017-12)Equine rotavirus group A (RVA) has been detected in several countries worldwide since its first detection in 1975. Currently, equine RVA is considered the major cause of dehydrating diarrhea in foals younger than 3 months, ... -
Molecular characterization of group A rotavirus strains detected in alpacas (Vicugna pacos) from Peru
(Microbiology Society, 2021-04)The alpaca is a very important social and economic resource for the production of fibre and meat for Andean communities. Peru is the main producer of alpacas. Group A rotavirus (RVA) has been sporadically detected in ... -
Molecular characterization of pestiviruses in fetal bovine sera originating from Argentina: evidence of circulation of HoBi-like viruses
(Frontiers Media, 2019-10)Serological evidence suggests that HoBi-like viruses, an emerging species within the Pestivirus genus of the Flaviviridae family, are in circulation in Argentina. While HoBi-like viruses were first isolated from Brazilian ...