• SARS-CoV-2 specific nanobodies neutralize different variants of concern and reduce virus load in the brain of h-ACE2 transgenic mice 

      Pavan, Florencia; Bok, Marina; Betanzos San Juan, Rafael; Malito, Juan Pablo; Marcoppido, Gisela Ariana; Franco, Diego Rafael; Militelo, Daniela Ayelen; Schammas, Juan Manuel; Bari, Sara Elizabeth; Stone, William B.; López, Krisangel; Porier, Danielle LaBrie; Muller, John Anthony; Auguste, Albert J.; Yuan, Lijuan; Wigdorovitz, Andres; Parreño, Gladys Viviana; Ibañez, Lorena Itat (MDPI, 2024-02)
      Since the beginning of the COVID-19 pandemic, there has been a significant need to develop antivirals and vaccines to combat the disease. In this work, we developed llama-derived nanobodies (Nbs) directed against the ...
    • Serological responses of Guinea pigs and heifers to eight different BoAHV-1 vaccine formulations 

      Camargo, Luana; Franklin, Yasmin Vieira; da Silva, Gustavo Feliciano Resende; Santos, Janaína Ferreira; Parreño, Gladys Viviana; Wigdorovitz, Andres; Gomes, Viviani (MDPI, 2024-06)
      Bovine alphaherpesvirus 1 (BoAHV-1) infection affects the production and reproductive performance of dairy and beef livestock, resulting in considerable economic losses. In addition to biosecurity measures, vaccination ...
    • Transient gene expression in serum-free suspension-growing mammalian cells for the production of foot-and-mouth disease virus empty capsids 

      Mignaqui, Ana Clara; Ruiz, Vanesa; Perret, Sylvie; St-Laurent, Gilles; Chahal, Parminder Singh; Transfiguracion, Julia; Sammarruco, Romina Ayelén; Gnazzo, Victoria; Durocher, Yves; Wigdorovitz, Andres (PLOS, 2013-08-20)
      Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. It produces severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ...