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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
(2017-01)Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ... -
Development of diagnostic tools for IBDV detection using plants as bioreactors
(SpringerOpen, 2020-05)Infectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. Multimeric ... -
Evasion of maternal antibody protection by an IBDV Argentine variant
(Elsevier, 2024-03)Infectious bursal disease (IBD) is a viral disease that affects the ability of chickens to produce humoral immune responses. One way to prevent the disease is the passage of maternally derived antibodies (MDA) from dams ... -
Immunomodulatory effect of baculovirus in chickens : how it modifies the immune response against infectious bursal disease virus
(2016)Several reports have shown that baculoviruses (BVs) have strong adjuvant properties on the mammalian immune system. Recent studies of our group demonstrated the ability of BV to stimulate the innate immunity in chickens. ... -
Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein
(Elsevier, 2015-09)Infectious Bursal Disease Virus (IBDV) causes a highly relevant poultry disease that affects young chickens causing, among other effects, immunosuppression. IBDV is a bi-segmented double stranded RNA virus. The smaller ORF ... -
Plant-based vaccine candidate against Infectious bursal disease: an alternative to inactivated vaccines for breeder hens
(Elsevier, 2019-08)Infectious bursal disease (IBD) is an acute, highly contagious immunosuppressive disease that affects young birds causing important economic losses in the poultry industry worldwide. Strict hygiene management together with ... -
Research Note : Characterization and phylodynamic analysis of new infectious bursal disease virus variants circulating in Argentina
(Elsevier, 2024-06)Infectious Bursal Disease is a highly contagious disease that affects young chickens and leads to significant economic losses. Its causal agent is a double-stranded RNA virus that, due to its high error rate during the ... -
Study of coinfection with local strains of infectious bursal disease virus and infectious bronchitis virus in specific pathogen-free chickens
(Elsevier, 2023-12)Immunosuppressive diseases cause great losses in the poultry industry, increasing the susceptibility to infections by other pathogens and promoting a suboptimal response to vaccination. Among them, infectious bursal disease ... -
Transient expression of VP2 in Nicotiana benthamiana and its use as a plant-based vaccine against Infectious Bursal Disease Virus
(Elsevier, 2013-05-28)Infectious Bursal Disease Virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds. This disease causes important economic losses in the poultry industry worldwide. ...