• A candidate gene survey of quantitative trait loci affecting chemical composition in tomato fruit 

      Bermúdez, Luisa; Urias, Ursula; Milstein, D.; Kamenetzky, Laura; Asís, Ramón; Fernie, Alisdair R.; Van Sluys, M.A.; Carrari, Fernando; Rossi, Magdalena (Society for Experimental Biology, 2008-07)
      In tomato, numerous wild-related species have been demonstrated to be untapped sources of valuable genetic variability, including pathogen-resistance genes, nutritional, and industrial quality traits. From a collection of ...
    • A tomato tocopherol-binding protein sheds light on intracellular a-tocopherol metabolism in plants 

      Bermudez Salazar, Luisa; del Pozo, Talía; Lira, Bruno Silvestre; Godoy, Fabiana de; Boos, Irene; Romano, Cecilia; Previtali, Viola; Almeida, Juliana; Brehelin, Claire; Asis, Ramón; Quadrana, Leandro Daniel; Demarco, Diego; Alseekh, Saleh; Salinas Gamboa, Rigel; Perez-Flores, Laura; Dominguez, Pia Guadalupe; Rothan, Christophe; Fernie, Alisdair R.; Gonzalez, Maurıcio; Stocker, Achim; Hemmerle, Andreas; Clausen, Mads Hartving; Carrari, Fernando; Rossi, Magdalena (Oxford University Press, 2018-11)
      Tocopherols are non-polar compounds synthesized in the plastids, which function as major antioxidants of the plant cells and are essential in the human diet. Both the intermediates and final products of the tocopherol ...
    • Allelic differences in a vacuolar invertase affect Arabidopsis growth at early plant development 

      Coluccio Leskow, Carla; Dominguez, Pia Guadalupe; Díaz Zirpolo, José Antonio; Obata, Toshihiro; Kamenetzky, Laura; Costa, Hernán; Taboga, Oscar Alberto; Marti, Hector Ruben; Keurentjes, Joost; Sulpice, Ronan; Ishihara, Hirofumi; Stitt, Mark; Fernie, Alisdair R.; Carrari, Fernando (2016)
      Improving carbon fixation in order to enhance crop yield is a major goal in plant sciences. By quantitative trait locus (QTL) mapping, it has been demonstrated that a vacuolar invertase (vac-Inv) plays a key role in ...
    • Coupling virus-induced gene silencing to exogenous green fluorescence protein expression provides a highly efficient system for functional genomics in arabidopsis and across all stages of tomato fruit development 

      Quadrana, Leandro Daniel; Rodriguez, Maria Cecilia; Bermudez Salazar, Luisa; Nunes Nesi, Adriano; Fernie, Alisdair R.; Descalzo, Adriana Maria; Asis, Ramón; Rossi, Magdalena; Asurmendi, Sebastian; Carrari, Fernando (2011-07)
      Since the advent of the postgenomic era, efforts have focused on the development of rapid strategies for annotating plant genes of unknown function. Given its simplicity and rapidity, virus-induced gene silencing (VIGS) ...
    • Crop metabolomics : from diagnostics to assisted breeding 

      Alseekh, Saleh; Bermudez Salazar, Luisa; De Haro, Luis Alejandro; Fernie, Alisdair R.; Carrari, Fernando (Springer, 2018-11)
      Background Until recently, plant metabolomics have provided a deep understanding on the metabolic regulation in individual plants as experimental units. The application of these techniques to agricultural systems subjected ...
    • Galacturonosyltransferase 4 silencing alters pectin composition and carbon partitioning in tomato 

      Godoy, Fabiana de; Bermúdez, Luisa; Lira, Bruno Silvestre; Souza, Amanda Pereira de; Elbl, Paula; Demarco, Diego; Alseekh, Saleh; Insani, Ester Marina; Buckeridge, Marcos; Almeida, Juliana; Grigioni, Gabriela Maria; Fernie, Alisdair R.; Carrari, Fernando; Rossi, Magdalena (2013-04)
      Pectin is a main component of the plant cell wall and is the most complex family of polysaccharides in nature. Its composition is essential for the normal growth and morphology pattern, as demonstrated by pectin-defective ...
    • Genetic dissection of vitamin E biosynthesis in tomato 

      Almeida de Souza, Juliana Beatriz; Quadrana, Leandro Daniel; Asis, Ramón; Setta, Nathalia; Godoy, Fabiana de; Bermúdez, Luisa; Otaiza, Santiago N.; Silva, Junia V. Corrêa da; Fernie, Alisdair R.; Carrari, Fernando; Rossi, Magdalena (Society for Experimental Biology, 2011-07)
      Vegetables are critical for human health as they are a source of multiple vitamins including vitamin E (VTE). In plants, the synthesis of VTE compounds, tocopherol and tocotrienol, derives from precursors of the shikimate ...
    • Identification and characterization of metabolite quantitative trait loci in tomato leaves and comparison with those reported for fruits and seeds 

      Nunes Nesi, Adriano; Alseekh, Saleh; Oliveira Silva, Franklin Magnum de; Omranian, Nooshin; Lichtenstein, Gabriel; Mirnezhad, Mohammad; Romero González, Roman R.; Sabio Y Garcia, Julia Veronica; Conte, Mariana; Leiss, Kirsten A.; Klinkhamer, Peter G. L.; Nikoloski, Zoran; Carrari, Fernando; Fernie, Alisdair R. (Springer, 2019-04)
      Introduction: To date, most studies of natural variation and metabolite quantitative trait loci (mQTL) in tomato have focused on fruit metabolism, leaving aside the identification of genomic regions involved in the ...
    • Integrating transcriptomic and metabolomic analysis to understand natural leaf senescence in sunflower 

      Moschen, Sebastian; Gonzalez, Sergio Alberto; Rivarola, Maximo Lisandro; Hopp, Horacio Esteban; Paniego, Norma Beatriz; Fernandez, Paula del Carmen; Heinz, Ruth Amelia; Bengoa Luoni, Sofia Ailin; Di Rienzo, Julio A.; Caro, María del Pilar; Tohge, Takayuki; Watanabe, Mutsumi; Hollmann, Julien; García-García, Francisco; Dopazo, Joaquín; Hoefgen, Rainer; Fernie, Alisdair R. (2016)
      Leaf senescence is a complex process, which has dramatic consequences on crop yield. In sunflower, gap between potential and actual yields reveals the economic impact of senescence. Indeed, sunflower plants are incapable ...
    • Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.) 

      Moschen, Sebastian Nicolas; Di Rienzo, Julio A.; Higgins, Janet; Tohge, Takayuki; Watanabe, Mutsumi; Gonzalez, Sergio Alberto; Rivarola, Maximo Lisandro; García-García, Francisco; Dopazo, Joaquín; Hopp, Horacio Esteban; Hoefgen, Rainer; Fernie, Alisdair R.; Paniego, Norma Beatriz; Fernandez, Paula Del Carmen; Heinz, Ruth Amelia (2017-07)
      Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the mechanisms involved in this tolerance remain ...
    • Metabolic analyses of interspecific tomato recombinant inbred lines for fruit quality improvement 

      Lopez, Mariana Gabriela; Zanor, María Inés; Pratta, Guillermo Raúl; Stegmayer, Georgina; Boggio, Silvana Beatriz; Conte, Mariana; Bermudez Salazar, Luisa; Coluccio Leskow, Carla; Rodríguez, Gustavo Rubén; Picardi, Liliana Amelia; Zorzoli, Roxana; Fernie, Alisdair R.; Milone, Diego Humberto; Asis, Ramón; Valle, Estela Marta; Carrari, Fernando (Springer, 2015-10)
      Elucidating the determinants of tomato nutritional value and fruit quality to introduce improved varieties on the international market represents a major challenge for crop biotechnology. Different strategies can be ...
    • Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes 

      Bazzini, Ariel Alejandro; Manacorda, Carlos Augusto; Tohge, Takayuki; Conti, Gabriela; Rodriguez, Maria Cecilia; Nunes Nesi, Adriano; Villanueva, Sofía; Fernie, Alisdair R.; Carrari, Fernando; Asurmendi, Sebastian (2011-12-12)
      Plant viral infections induce changes including gene expression and metabolic components. Identification of metabolites and microRNAs (miRNAs) differing in abundance along infection may provide a broad view of the pathways ...
    • Multiomics analyses reveal the roles of the ASR1 transcription factor in tomato fruits 

      Dominguez, Pia Guadalupe; Conti, Gabriela; Duffy, Tomas; Insani, Ester Marina; Alseekh, Saleh; Asurmendi, Sebastian; Fernie, Alisdair R.; Carrari, Fernando (Oxford University Press, 2021-09)
      The transcription factor ASR1 (ABA, STRESS, RIPENING 1) plays multiple roles in plant responses to abiotic stresses as well as being involved in the regulation of central metabolism in several plant species. However, despite ...
    • Natural occurring epialleles determine vitamin E accumulation in tomato fruits 

      Quadrana, Leandro Daniel; Almeida de Souza, Juliana Beatriz; Asis, Ramón; Duffy, Tomas; Dominguez, Pia Guadalupe; Bermudez Salazar, Luisa; Conti, Gabriela; Silva, Junia V. Corrêa da; Peralta, Iris Edith; Colot, Vincent; Asurmendi, Sebastian; Fernie, Alisdair R.; Rossi, Magdalena; Carrari, Fernando Oscar (2014-07)
      Vitamin E (VTE) content is a low heritability nutritional trait for which the genetic determinants are poorly understood. Here, we focus on a previously detected major tomato VTE quantitative trait loci (QTL; mQTL9-2-6) ...
    • Phytochrome-dependent temperature perception modulates isoprenoid metabolism 

      Bianchetti, Ricardo; De Luca, Belen; De Haro, Luis Alejandro; Rosado, Daniele; Demarco, Diego; Conte, Mariana; Bermudez Salazar, Luisa; Freschi, Luciano; Fernie, Alisdair R.; Michaelson, Louise V.; Haslam, Richard P.; Rossi, Magdalena; Carrari, Fernando (American Society of Plant Biologists, 2020-07)
      Changes in environmental temperature influence many aspects of plant metabolism; however, the underlying regulatory mechanisms remain poorly understood. In addition to their role in light perception, phytochromes (PHYs) ...
    • Silencing of the tomato Sugar Partitioning Affecting protein (SPA) modifies sink strength through a shift in leaf sugar metabolism 

      Bermudez Salazar, Luisa; de Godoy, Fabiana; Baldet, Pierre; Demarco, Diego; Osorio, Sonia; Quadrana, Leandro Daniel; Almeida de Souza, Juliana Beatriz; Asis, Ramón; Gibon, Yves; Fernie, Alisdair R.; Rossi, Maria Magdalena; Carrari, Fernando (Wiley; Society for Experimental Biology, 2014-03)
      Limitations in our understanding about the mechanisms that underlie source-sink assimilate partitioning are increasingly becoming a major hurdle for crop yield enhancement via metabolic engineering. By means of a ...
    • The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato 

      Coluccio Leskow, Carla; Conte, Mariana; del Pozo, Talía; Bermudez Salazar, Luisa; Lira, Bruno Silvestre; Gramegna, Giovanna; Baroli, Irene; Burgos, Estanislao; Zavallo, Diego; Kamenetzky, Laura; Asis, Ramón; Gonzalez, Maurıcio; Fernie, Alisdair R.; Rossi, Magdalena; Osorio, Sonia; Carrari, Fernando (Oxford University Press, 2021-03)
      Sucrose metabolism is important for most plants, both as the main source of carbon and via signaling mechanisms that have been proposed for this molecule. A cleaving enzyme, invertase (INV) channels sucrose into sink ...
    • The genetic architecture of photosynthesis and plant growthrelated traits in tomato 

      Oliveira Silva, Franklin Magnum de; Lichtenstein, Gabriel; Alseekh, Saleh; Rosado‐Souza, Laise; Conte, Mariana; Fuentes Suguiyama, Vanessa; Lira, Bruno Silvestre; Fanourakis, Dimitrios; Usadel, Björn; Lopes Bhering, Leonardo; DaMatta, Fábio M.; Sulpice, Ronan; Araújo, Wagner L.; Rossi, Magdalena; de Setta, Nathalia; Fernie, Alisdair R.; Carrari, Fernando; Nunes Nesi, Adriano (Wiley, 2018-02)
      To identify genomic regions involved in the regulation of fundamental physiological processes such as photosynthesis and respiration, a population of Solanum pennellii introgression lines was analyzed. We determined ...
    • The genome of the stress-tolerant wild tomato species Solanum pennellii 

      Bolger, Anthony; Scossa, Federico; Bolger, Marie E.; Lanz, Christa; Maumus, Florian; Tohge, Takayuki; Quesneville, Hadi; Alseekh, Saleh; Sørensen, Iben; Lichtenstein, Gabriel; Fich, Eric A.; Conte, Mariana; Keller, Heike; Schneeberger, Korbinian; Schwacke, Rainer; Ofner, Itai; Vrebalov, Julia; Xu, Yimin; Osorio, Sonia; Aflitos, Saulo Alves; Schijlen, Elio; Jiménez-Goméz, José M.; Ryngajllo, Malgorzata; Kimura, Seisuke; Kumar, Ravi; Koenig, Daniel; Headland, Lauren R.; Maloof, Julin N.; Sinha, Neelima; van Ham, Roeland C. H. J.; Lankhorst, René Klein; Mao, Linyong; Vogel, Alexander; Arsova, Borjana; Panstruga, Ralph; Fei, Zhangjun; Rose, Jocelyn K. C.; Zamir, Dani; Carrari, Fernando; Giovannoni, James J.; Weigel, Detlef; Usadel, Björn; Fernie, Alisdair R. (Nature Publishing Group, 2014-09)
      Solanum pennellii is a wild tomato species endemic to Andean regions in South America, where it has evolved to thrive in arid habitats. Because of its extreme stress tolerance and unusual morphology, it is an important ...
    • Transcriptional regulation of tocopherol biosynthesis in tomato 

      Quadrana, Leandro Daniel; Almeida de Souza, Juliana Beatriz; Otaiza, Santiago N.; Duffy, Tomas; Silva, Junia V. Corrêa da; Godoy, Fabiana de; Asís, Ramón; Bermúdez, Luisa; Fernie, Alisdair R.; Carrari, Fernando; Rossi, Magdalena (Springer, 2013-02)
      Tocopherols, compounds with vitamin E (VTE) activity, are potent lipid-soluble antioxidants synthesized only by photosynthetic organisms. Their biosynthesis requires the condensation of phytyl-diphosphate and homogentisate, ...