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Autores
Mostrando ítems 1-20 de 20
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A safe and effective vaccine against bovine leukemia virus
Suarez Archilla, Guillermo; Gutierrez, Gerónimo; Camussone, Cecilia; Calvinho, Luis Fernando; Abdala, Alejandro Ariel; Alvarez, Irene; Petersen, Marcos; Franco, Lautaro Nahuel; De Stefano, Gabriel Alejandro; Monti, Gustavo; Jacques, Jean-Rock; Joris, Thomas; Willems, Luc; Trono, Karina Gabriela (Frontiers Media, 2022-08)Previous attempts to develop a vaccine against bovine leukemia virus (BLV) have not been successful because of inadequate or short-lived stimulation of all immunity components. In this study, we designed an approach based ... -
Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis
Molineri, Ana Ines; Camussone, Cecilia; Zbrun, María Virginia; Suarez Archilla, Guillermo; Cristiani, Mariana; Neder, Veronica Elizabeth; Calvinho, Luis Fernando; Signorini Porchiett, Marcelo Lisandro (Elsevier, 2021-03)Staphylococcus aureus, one of the main contagious mastitis pathogens worldwide, is characterized for causing chronic intramammary infections that respond poorly to antimicrobial therapy, disseminating within the herd leading ... -
Antimicrobial resistance of Streptococcus uberis isolated from bovine mastitis: Systematic review and meta-analysis
Miotti, Camila; Cicotello, Joaquin; Suarez Archilla, Guillermo; Neder, Veronica Elizabeth; Alvarado, Wanda; Calvinho, Luis Fernando; Signorini Porchiett, Marcelo Lisandro; Camussone, Cecilia; Zbrun, María Virginia; Molineri, Ana Ines (Elsevier, 2023-11)Streptococcus uberis is one of the most common pathogens associated with bovine mastitis, commonly treated with antimicrobials (AM), favoring the appearance of antimicrobial resistance (AMR). The objective of this work was ... -
Comparison of phenotypic tests for detecting penicillin G resistance with presence of blaZ gene in Staphylococcus aureus isolated from bovine intramammary infections
Russi, Norma B.; Maito, Julia; Dieser, Silvana Andrea; Renna, Maria Sol; Signorini, Marcelo; Camussone, Cecilia; Neder, Veronica Elizabeth; Pol, Martín; Tirante, Liliana; Odierno, Liliana Mónica; Calvinho, Luis Fernando (2015-08)Few studies have described the relationship between genotypic and phenotypic methods for detecting penicillin resistance in Staphylococcus aureus isolated from bovine intramammary infection (IMI). Six phenotypic methods ... -
Comparison of real-time PCR and nested PCR based on the HlyA gene for the detection of Listeria monocytogenes. Application on cheese samples
Zbrun, Maria Virginia; Moreno, Nadia; Camussone, Cecilia; Signorini Porchiett, Marcelo Lisandro; Primo, María Evangelina (Springer, 2024-04)The aim of the present study was to compare the performance of a nested polymerase chain reaction (nPCR) and a real-time PCR based on the amplification of the HlyA gene from Listeria monocytogenes using a plasmid DNA ... -
Desarrollo de un inmunógeno prototípico para el control de mastitis bovinas causadas por Staphylococcus aureus
Camussone, Cecilia (Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, 2012)Staphylococcus aureus es el patógeno más frecuentemente aislado de casos de mastitis bovina en Argentina y el mundo. Las particulares características de las infecciones intramamarias por S. aureus, han llevado a la búsqueda ... -
Differential immune response to two Staphylococcus aureus strains with distinct adaptation genotypes after experimental intramammary infection of dairy cows
Engler, Carolina; Renna, María Sol; Beccaria, Camila; Silvestrini, Paula; Pirola, Silvana I.; Pereyra, Elizabet Amanda Lorena; Baravalle, Celina; Camussone, Cecilia; Monecke, Stefan; Calvinho, Luis Fernando; Dallard, Bibiana Elisabet (Elsevier, 2022-11)The aim of this study was to evaluate and compare the ability of two S. aureus strains with different adaptation genotypes (low and high) to the bovine mammary gland (MG) to establish an intramammary infection (IMI) and ... -
Efficacy of immunization with a recombinant S. aureus vaccine formulated with liposomes and ODN-CpG against natural S. aureus intramammary infections in heifers and cows
Camussone, Cecilia; Reidel, Ivana Gabriela; Molineri, Ana Ines; Cicotello, Joaquin; Miotti, Camila; Suarez Archilla, Guillermo; Curti, C.C.; Veaute, Carolina Melania Isabel; Calvinho, Luis Fernando (Elsevier, 2022-07)The aims of the present study were to evaluate the ability of a subunit vaccine composed of recombinant molecules of α-toxin, β-toxin, FnBPA and ClfA, formulated with cationic liposomes and CpG-ODN, to confer protection ... -
Evaluation of the humoral immune response to a multicomponent recombinant vaccine against S. aureus in healthy pregnant heifers
Pujato, Nazarena; Camussone, Cecilia; Renna, María Sol; Perrig, Melina Soledad; Morein, Bror; Calvinho, Luis Fernando; Marcipar, Iván Sergio (2018-05)Staphylococcus aureus is a worldwide pathogen that causes mastitis in dairy herds. Shortcomings in control programs have encouraged the development of vaccines against this pathogen. This study evaluated the vaccine candidate ... -
Factores de virulencia de Staphylococcus aureus asociados con infecciones mamarias en bovinos: relevancia y rol como agentes inmunógenos = Virulence factors of Staphylococcus aureus associated with intramammary infections in cows: Relevance and role as immunogens
Camussone, Cecilia; Calvinho, Luis Fernando (2013)Staphylococcus aureus es el microorganismo causante de mastitis bovina más prevalente en Argentina y en el mundo. La falta de efectividad frente a este organismo de los métodos tradicionales de control, basados en la higiene ... -
Functional role of antibodies generated in heifers through immunization with Staphylococcus aureus vaccines in invasion and phagocytosis assays
Renna, María Sol; Pereyra, Elizabet Amanda Lorena; Baravalle, Celina; Camussone, Cecilia; Dallard, Bibiana Elisabet; Marcipar, Iván Sergio; Calvinho, Luis Fernando (2014-11)A successful Staphylococcus aureus vaccine should elicit a long-term antibody response that prevents establishment of the infection. The aim of the present study was to evaluate the functional role of antibodies raised ... -
Genotypic and phenotypic detection of capsular polysaccharide and biofilm formation in Staphylococcus aureus isolated from bovine milk collected from Brazilian dairy farms
Salimena, Alessandra P.S.; Lange, Carla C.; Camussone, Cecilia; Signorini, Marcelo; Calvinho, Luis Fernando; Brito, María A.V.P.; Borges, Cristiano A.V.; Guimaraes, Alessandro S.; Ribeiro, Joao B.; Mendonca, Leticia C.; Piccoli, Roberta H. (2016-12)Staphylococcus aureus is a pathogen that frequently causes mastitis in bovine herds worldwide. This pathogen produces several virulence factors, including cell-associated adhesins, toxic and cytolytic exoproteins, and ... -
Humoral immune response of pregnant goats to two Corynebacterium pseudotuberculosis bacterin formulations
Auad, Jordana; Cerutti, Julieta; Cooper, Laura Gabriela; Camussone, Cecilia; Lozano, Natalia A.; Crespo, Francisco M.; Lozano, Alejandro (Facultad de Ciencias Veterinarias, Universidad Austral de Chile, 2018)Caseous lymphadenitis is a chronic suppurative bacterial disease caused by Corynebacterium pseudotuberculosis, and it has a high prevalence among small ruminants. Different vaccine preparations have been employed to control ... -
Immune response and functional role of antibodies raised in heifers against a Staphylococcus aureus CP5 lysate and recombinant antigens vaccine formulated with Iscom Matrix adjuvant
Camussone, Cecilia; Pujato, Nazarena; Renna, María Sol; Veaute, Carolina Melania Isabel; Morein, Bror; Marcipar, Iván Sergio; Calvinho, Luis Fernando (2014-12-15)Staphylococcus aureus is the most frequently isolated pathogen from bovine intramammary infections worldwide. Commercially available vaccines for mastitis control are composed either of S. aureus lysates or inactivated ... -
Immune response of heifers against a Staphylococcus aureus CP5 whole cell and lysate vaccine formulated with ISCOM Matrix adjuvant
Camussone, Cecilia; Veaute, Carolina Melania Isabel; Pujato, Nazarena; Morein, Bror; Marcipar, Iván Sergio; Calvinho, Luis Fernando (2014-02)Staphylococcus aureus is the most frequently isolated pathogen from bovine intramammary infections worldwide. Commercially available vaccines for mastitis control are composed either of S. aureus lysates or whole-cells ... -
Immune response of heifers against a Staphylococcus aureus CP5 whole cell vaccine formulated with ISCOMATRIX™ adjuvant
Camussone, Cecilia; Veaute, Carolina Melania Isabel; Porporatto, Carina; Morein, Bror; Marcipar, Iván Sergio; Calvinho, Luis Fernando (2013-02)The shortcomings of Staphylococcus aureus vaccines to control bovine mastitis have been attributed to insufficient capacity of the vaccines to induce opsonizing antibodies and to stimulate cellular immune responses. Types ... -
Liposomal and CpG-ODN formulation elicits strong humoral immune responses to recombinant Staphylococcus aureus antigens in heifer calves
Reidel, Ivana Gabriela; Camussone, Cecilia; Suarez Archilla, Guillermo Alejandro; Calvinho, Luis Fernando; Veaute, Carolina Melania Isabel (Elsevier, 2019-05-01)Bovine mastitis caused by Staphylococcus aureus is a serious problem in dairy production and effective immunoprophylaxis is an unmet goal so far. The objective of this work was to assess the humoral immune response of ... -
Risk factors of S. aureus intramammary infection in pre partum dairy heifers under grazing conditions and molecular characterization of isolates from heifers and cows
Camussone, Cecilia; Molineri, Ana Ines; Signorini, Marcelo; Neder, Veronica Elizabeth; Vitulich, Carlos Alberto; Calvinho, Luis Fernando (Cambridge University Press, 2020-02)The aims of the research reported here were to identify potential risk factors associated with the presence of Staphylococcus aureus intramammary infection (IMI) in pre partum dairy heifers on 17 dairy farms from three ... -
Survey of potential factors involved in the low frequency of CP5 and CP8 expression in Staphylococcus aureus isolates from mastitis of dairy cattle from Argentina, Chile, and Uruguay
Ambroggio, Maria Belen; Perrig, Melina Soledad; Camussone, Cecilia; Pujato, Nazarena; Bertón, Alicia; Gianneechini, Edgardo; Alvarez, Silvia; Marcipar, Ivan Sergio; Calvinho, Luis Fernando; Barbagelata, Maria Sol (2018-08)Staphylococcus aureus produces capsular polysaccharides (CPs) both in vivo and under defined culture conditions being serotypes 5 and 8 the most prevalent. S. aureus isolates that fail to produce CP5 or CP8 are defined as ... -
Which are important targets in development of S. aureus mastitis vaccine?
Scali, F.; Camussone, Cecilia; Calvinho, Luis Fernando; Cipolla, M.; Zecconi, A. (2015-06)Staphylococcus aureus represents one of the leading causes of mastitis in dairy cows worldwide. S. aureus IMI have variable outcomes due to virulence of the strain involved, immune defenses of the host, and by antibiotic ...