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Mostrando ítems 1-12 de 12

    • A new piroplasmid species infecting dogs: morphological and molecular characterization and pathogeny of Babesia negevi n. sp. 

      Baneth, Gad; Nachum‑Biala, Yaarit; Birkenheuer, Adam Joseph; Schreeg, Megan Elizabeth; Prince, Hagar; Florin-Christensen, Monica; Schnittger, Leonhard; Aroch, Itamar (BMC, 2020-04)
      Introduction: Babesiosis is a protozoan tick-borne infection associated with anemia and life-threatening disease in humans, domestic and wildlife animals. Dogs are infected by at least six well-characterized Babesia spp. ...

    • Babesia spp. in ticks and wildlife in different habitat types of Slovakia 

      Hamšíkova, Zuzana; Kazimirová, Mária; Harustiakova, Danka; Mahrikova, Lenka; Slovak, Mirko; Berthová, Lenka; Kocianova, Elena; Schnittger, Leonhard (2016)
      Background: Babesiosis is an emerging and potentially zoonotic disease caused by tick-borne piroplasmids of the Babesia genus. New genetic variants of piroplasmids with unknown associations to vectors and hosts are ...

    • Characterization of GASA-1, a new vaccine candidate antigen of Babesia bovis 

      Flores, Daniela; Rodriguez, Anabel Elisa; Tomazic, Mariela Luján; Torioni, Susana Marta; Echaide, Ignacio Eduardo; Zamorano, Patricia Ines; Langellotti, Cecilia Ana; Araujo, Flabio Ribeiro de; Rolls, Peter; Schnittger, Leonhard; Florin-Christensen, Mónica (Elsevier, 2020-11)
      Surface proteins bound to the cell membrane by glycosylphosphatidylinositol (GPI) anchors are considered essential for the survival of pathogenic protozoans. In the case of the tick-transmitted hemoparasite Babesia bovis, ...

    • Evidence for extensive genetic diversity and substructuring of the Babesia bovis metapopulation 

      Flores, Daniela; Minichiello, Y.; Araujo, Flabio Ribeiro de; Shkap, V.; Benitez, Daniel Francisco; Echaide, Ignacio Eduardo; Rolls, P.; Mosqueda, J.; Pacheco, Maria Gabriela; Petterson, Maria Elizabeth; Florin-Christensen, Mónica; Schnittger, Leonhard (2013-11)
      Babesia bovis is a tick-transmitted haemoprotozoan and a causative agent of bovine babesiosis, a cattle disease that causes significant economic loss in tropical and subtropical regions. A panel of nineteen micro- and ...

    • High genetic diversity and differentiation of the babesia ovis population in Turkey 

      Mira, Anabela; Unlu, Ahmet Hakan; Bilgic, Huseyin Bilgin; Bakirci, Serkan; Hacilarlioglu, Selin; Karagenc, Tulin; Carletti, Tamara; Weir, William; Shiels, Brian; Shkap, Varda; Aktas, Munir; Florin‐Christensen, Mónica; Schnittger, Leonhard (Wiley, 2020-07)
      Babesia ovis is a tick‐transmitted protozoan haemoparasite causing ovine babesiosis in sheep and goats leading to considerable economic loss in Turkey and neighbouring countries. There are no vaccines available, therapeutic ...

    • Highly sensitive nested PCR and rapid immunochromatographic detection of Babesia bovis and Babesia bigemina infection in a cattle herd with acute clinical and fatal cases in Argentina 

      Ganzinelli, Sabrina Belen; Benitez, Daniel Francisco; Gantuya, Sambuu; Guswanto, Azirwan; Florin-Christensen, Mónica; Schnittger, Leonhard; Igarashi, Ikuo (Wiley, 2020-07)
      Bovine babesiosis is a tick‐transmitted haemoparasitic disease caused by Babesia bovis and B. bigemina affecting cattle of tropical and subtropical regions around the world. Pathogens are transmitted by the tick vector ...

    • In Silico Survey and Characterization of Babesia microti Functional and Non-Functional Proteases 

      Florin-Christensen, Monica; Wieser, Sara Nathaly; Suarez, Carlos E.; Schnittger, Leonhard (MDPI, 2021-11)
      Human babesiosis caused by the intraerythrocytic apicomplexan Babesia microti is an expanding tick-borne zoonotic disease that may cause severe symptoms and death in elderly or immunocompromised individuals. In light of ...

    • International interlaboratory validation of a nested PCR for molecular detection of Babesia bovis and Babesia bigemina, causative agents of bovine babesiosis 

      Ganzinelli, Sabrina Belen; Byaruhanga, Charles; Primo, María Evangelina; Lukanji, Zinathi; Sibeko, Kgomotso; Matjila, Tshepo; Neves, Luis; Benitez, Daniel Francisco; Enkhbaatar, Batmagnai; Nugraha, Arifin Budiman; Igarashi, Ikuo; Florin-Christensen, Mónica; Schnittger, Leonhard (Elsevier, 2022-04)
      Babesia bovis and B. bigemina are tick-transmitted parasites causing bovine babesiosis, characterized by significant morbidity and mortality leading to economic losses to the livestock industry in tropical and subtropical ...

    • The glycosylphosphatidylinositol-anchored protein repertoire of Babesia bovis and its significance for erythrocyte invasion 

      Rodriguez, Anabel Elisa; Florin-Christensen, Mónica; Flores, Daniela; Echaide, Ignacio Eduardo; Suarez, Carlos Esteban; Schnittger, Leonhard (2014-04)
      Glycosylphosphatidylinositol-anchored proteins are abundant on the surface of pathogenic protozoans and might play an important role for parasite survival. In the present work, the relevance of GPI-anchored proteins for ...

    • Unraveling the complexity of the rhomboid serine protease 4 family of Babesia bovis using bioinformatics and experimental studies 

      Gallenti, Romina Josefina; Hussein, Hala E.; Alzan, Heba F.; Suarez, Carlos Esteban; Ueti, Massaro W.; Asurmendi, Sebastian; Benitez, Daniel Francisco; Araujo, Flabio Ribeiro de; Rolls, Peter; Sibeko, Kgomotso; Schnittger, Leonhard; Florin-Christensen, Mónica (MDPI, 2022-03)
      Babesia bovis, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and subtropical regions around the world. In the apicomplexans Toxoplasma gondii and Plasmodium falciparum, rhomboid serine protease 4 ...

    • Vaccination against babesiosis using recombinant GPI-anchored proteins 

      Wieser, Sara Nathaly; Schnittger, Leonhard; Florin-Christensen, Monica; Delbecq, Stephane; Schetters, Theo (Elsevier, 2019-01)
      The increase in human babesiosis is of major concern to health authorities. In the USA, most of these cases are due to infections with Babesia microti, whereas in Europe B. divergens is the major cause of clinical disease ...

    • Vaccines against bovine babesiosis: where we are now and possible roads ahead 

      Florin-Christensen, Mónica; Suarez, Carlos Esteban; Rodriguez, Anabel Elisa; Flores, Daniela; Schnittger, Leonhard (Cambridge University Press, 2014-10)
      Bovine babesiosis caused by the tick-transmitted haemoprotozoans Babesia bovis, Babesia bigemina and Babesia divergens commonly results in substantial cattle morbidity and mortality in vast world areas. Although existing ...