Browsing Instituto de Biotecnología by Author 

Browsing Instituto de Biotecnología by Author "20208393295"

Now showing items 21-40 of 44

    • Limited usefulness of the IS6110 touchdown-PCR in blood for tuberculin skin test false-negative cattle with serological response to Mycobacterium bovis 

      Encinas, Micaela; Ferrara Muñiz, Ximena; Sammarruco, Romina Ayelén; Ruiz Menna, Victoria Aymara; Garro, Carlos Javier; Delgado, Fernando Oscar; Macías, Analía; Magnano, Gabriel; Zumarraga, Martin Jose; Garbaccio, Sergio Gabriel; Eirin, Maria Emilia (Frontiers Media, 2024-05)
      Ante-mortem diagnosis of bovine tuberculosis (bTB) is based mainly on the tuberculin skin test (TST) and the ɣ-IFN release assay (IGRA). Some infected animals escape screening tests, thus, limit herd sanitation. Previous ...

    • Matrix assisted laser desorption ionization-time-of-flight mass spectrometry identification of mycobacterium bovis in bovinae 

      Bacanelli, Gisele; Olarte, Larissa C.; Silva, Marcio Roberto; Rodrigues, Rudielle A.; Carneiro, Paulo A. M.; Kannene, John B.; Pasquatti, Taynara N.; Takatani, Haruo; Zumarraga, Martin Jose; Etges, Rodrigo N.; Araujo, Flabio Ribeiro de; Verbisck, Newton V. (The Japanese Society of Veterinary Science, 2019-10)
      In this study, Matrix Assisted Laser Desorption Ionization-Time-of-Flight (MALDI-TOF) mass spectrometry was used to identify Mycobacterium bovis from cattle and buffalo tissue isolates from the North and South regions of ...

    • Molecular characterization of Mycobacterium bovis infection in cattle and buffalo in Amazon Region, Brazil 

      Carneiro, Paulo A.M.; Pasquatti, Taynara N.; Takatani, Haruo; Zumarraga, Martin Jose; Marfil, Maria Jimena; Barnard, Christian; Fitzgerald, Scott D.; Abramovitch, Robert B.; Araujo, Flabio Ribeiro de; Kaneene, John B. (Wiley, 2020-02)
      The aim of this study was to characterize Mycobacterium bovis from cattle and buffalo tissue samples, from two Brazilian states, and to analyse their genetic diversity by spoligotyping. Tissue samples from tuberculosis ...

    • Mycobacterioses in dogs and cats from Buenos Aires, Argentina 

      Barandiaran, Soledad; Martinez Vivot, Marcela; Falzoni, Elvira; Marfil, Maria Jimena; Perez Tort, Gabriela; Rovatti, Paula; Fernandez, Mónica; Iachini, Ricardo; Satek, Fernanda; Duchene, Adriana; Zumarraga, Martin Jose (Sage Publications, 2017-09)
      Mycobacterioses can produce nonspecific clinical signs in dogs and cats that make diagnosis difficult. Furthermore, the full characterization of mycobacterial agents is not always possible or practical. We characterized ...

    • Mycobacterium bovis ESAT-6, CFP-10 and EspC antigens show high conservation among field isolates 

      Encinas, Micaela; Marfil, Maria Jimena; Garbaccio, Sergio Gabriel; Barandiaran, Soledad; Huertas, Pablo Sebastian; Morsella, Claudia Graciela; Macias, Analía; Magnano, Gabriel; Zapata, L.; Bigi, Fabiana; Cataldi, Angel Adrian; Paolicchi, Fernando; Zumarraga, Martin Jose; Eirin, Maria Emilia (Elsevier, 2018-07)
      ESAT-6, CFP-10 and EspC are virulence factors that have been extensively assayed for bovine and human tuberculosis diagnosis due their potent T-cell inducing activities. While polymorphisms of ESAT-6 and CFP-10 were analyzed, ...

    • Mycobacterium bovis infection in a horse with granulomatous enterocolitis 

      Sarradell, Javier E.; Alvarez, Julio; Biscia, Mariana; Zumarraga, Martin Jose; Wunschmann, Arno; Armien, Aníbal G.; Perez, Andrés M. (Sage Publications, 2015-03)
      A 2-year-old dappled Percheron horse had a wasting condition that did not respond to antibiotic treatments and ultimately resulted in death. Thickening of the wall of the large colon and enlargement of the mesenteric lymph ...

    • Mycobacterium intracellulare infection in a capybara (Hydrochoerus hydrochaeris) 

      Pezzone, Natalia; Eberhardt, Ayelén; Fernandez, Analía; Garbaccio, Sergio Gabriel; Zumarraga, Martin Jose; Gioffre, Andrea; Magni, Carolina; Beldomenico, Pablo Martín; Marini, M. Rocío; Canal, Ana María (American Association of Zoo Veterinarians, 2013-12)
      This report describes the first case of Mycobacterium intracellulare infection with typical granulomatous lesions of mycobacteriosis in a capybara (Hydrochoerus hydrochaeris). The individual was a captive-bred young female, ...

    • Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina 

      Marfil, Maria Jimena; Barandiaran, Soledad; Zumarraga, Martin Jose; Germani, Ludmila; Faccini, Tamara; Linares, Marcelo; Capra, Silvana; Gramajo, Laura; Martinez Vivot, Marcela; Falzoni, Elvira (Springer, 2022-02)
      Mycobacterium bovis and Mycobacterium avium are the most important Mycobacteria isolated from diseased dogs, but Mycobacterium tuberculosis can be isolated as well, especially when close contact with humans exists. Free ...

    • Non-tuberculous mycobacteria isolated at the end of the world 

      Ferrara Muñiz, Ximena; Tortone, Claudia Andrea; Oriani, Delia Susana; Garro, Carlos Javier; Garbaccio, Sergio Gabriel; Farace, Pablo Daniel; Encinas, Micaela; Eirin, Maria Emilia; Zumarraga, Martin Jose (European Society of Mycobacteriology, 2024-06)
      Introduction: Non-tuberculous mycobacteria (NTM) are a group of mycobacteria widely distributed in the environment (e.g. soil and water). NTM can also cause infections in different mammals, mostly in immunocompromised ...

    • Pathogenesis of domestic pigs submitted to mycobacterial sensitizations previous to experimental infection with Mycobacterium bovis 

      Cuerda, Maria Ximena; Colombatti Olivieri, Maria Alejandra; Gravisaco, María José; Marfil, Maria Jimena; Barandiaran, Soledad; Sevilla, Iker A.; Garrido, Joseba M.; Moyano, Roberto Damian; Zumarraga, Martin Jose; Romano, Maria Isabel; Juste, Ramón A.; Santangelo, María De La Paz (INIA (España), 2022-03)
      Aim of study: To demonstrate the virulence of a Mycobacterium bovis local pig isolate in order to contribute to a better understanding of the pathological and immunological consequences of M. bovis infection in previous ...

    • Patterns and processes of mycobacterium bovis evolution revealed by phylogenomic analyses 

      Patané, José S.L.; Martins Jr, Joaquim; Castelão, Ana Beatriz C.; Nishibe, Christiane; Montera, Luciana; Bigi, Fabiana; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Fonseca Junior, Antônio; Roxo, Eliana; Osório, Ana Luiza Alves Rosa; Jorge, Klaudia dos Santos Goncalves; Thacker, Tyler C.; Almeida, Nalvo Franco; Araujo, Flabio Ribeiro de; Setubal, Joâo C. (Oxford University Press, 2017-03)
      Mycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South ...

    • Polymorphisms of 20 regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis 

      Bigi, María Mercedes; Blanco, Federico Carlos; Araujo, Flabio Ribeiro de; Thacker, Tyler C.; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Soria, Marcelo Abel; Bigi, Fabiana (2016)
      Mycobacterium tuberculosis and Mycobacterium bovis are responsible for tuberculosis in humans and animals, respectively. Both species are closely related and belong to the Mycobacterium tuberculosis complex (MTC). M. ...

    • Pre-columbian mycobacterial genomes reveal seals as a source of new world human tuberculosis 

      Bos, Kirsten I.; Harkins, Kelly M.; Herbig, Alexander; Coscolla, Mireia; Weber, Nico; Comas, Iñaki; Forrest, Stephen A.; Bryant, Josephine M.; Harris, Simon R.; Schuenemann, Verena J.; Campbell, Tessa J.; Majander, Kerrtu; Wilbur, Alicia K.; Guichon, Ricardo A.; Steadman, Dawnie L. Wolfe; Cook, Della Collins; Niemann, Stefan; Behr, Marcel A.; Zumarraga, Martin Jose; Bastida, Ricardo; Huson, Daniel; Nieselt, Kay; Young, Douglas; Parkhill, Julian; Buikstra, Jane E.; Gagneux, Sebastien; Stone, Anne C.; Krause, Johannes (Springer Nature, 2014-08)
      Modern strains of Mycobacterium tuberculosis from the Americas are closely related to those from Europe, supporting the assumption that human tuberculosis was introduced post-contact1. This notion, however, is incompatible ...

    • Prevalence and species diversity of nontuberculous mycobacteria in drinking water supply system of Bahía Blanca City, Argentina 

      Oriani, Alejandra Soledad; Marfil, Maria Jimena; Zumarraga, Martin Jose; Baldini, Mónica Diana (Wolters Kluwer; Asian African Society of Mycobacteriology, 2019-06)
      Background: There is evidence that tap water is the vehicle through which nontuberculous mycobacteria (NTM) infect or colonize the human body. The objective of this study was to determine the presence and diversity of NTM ...

    • Replication and transmission features of two experimental vaccine candidates against bovine tuberculosis subcutaneously administrated in a murine model 

      Ferrara Muñiz, Ximena; Garcia, Elizabeth Andrea; Blanco, Federico Carlos; Bigi, Fabiana; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Eirin, Maria Emilia (Elsevier, 2022-05)
      Cattle vaccination is an attractive approach in compliance with control and eradication programs against Bovine Tuberculosis (bTB). Today, there is no anti bTB vaccine licensed. Two vaccine candidates, MbΔmce2 and MbΔmce2-phoP ...

    • Spatial distribution of Mycobacterium bovis spoligotypes in cattle from the state of Minas Gerais, Brazil 

      Souza, Mariana Assunção de; Lopes, Thaís Aline Carolino; Silva, Brendhal Almeida; Bombonato, Nadia Grandi; Dib, Cristina Corsi; Marfil, Maria Jimena; Zumarraga, Martin Jose; Lima, Anna Monteiro Correia (Springer, 2022-07)
      Genotyping methods have led to a better understanding of the epidemiology of Mycobacterium bovis (M. bovis) infection, and its transmission dynamics, as well as the possible phylogenetic relationships between Mycobacterium ...

    • Surveillance and characterization of drug‑resistant mycobacterium tuberculosis isolated in a reference hospital from Argentina during 8 years’ period 

      Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Mancino, María Belén; Zumarraga, Martin Jose; Morcillo, Nora (Wolters Kluwer, 2019-09)
      Background: Argentina is considered a country with a middle tuberculosis (TB) incidence. However, according to the last national epidemiological report released in 2018, since 2013, the trends are steadily increasing. The ...

    • Transmissibility of Mycobacterium pinnipedii in a murine model 

      Marfil, Maria Jimena; Blanco, Federico Carlos; Colombatti Olivieri, Maria Alejandra; Eirin, Maria Emilia; Zumarraga, Martin Jose (Frontiers Media, 2024-03)
      The causative agent of tuberculosis in pinnipeds is Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis complex (MTC). The natural hosts are pinnipeds; however, other non-marine mammals, including humans, ...

    • Tuberculosis bovina : transmisibilidad de cepas de Mycobacterium bovis y detección de micobacterias en menudencias comercializadas en bocas de expendio de carne 

      Marfil, Maria Jimena (Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2019)
      La tuberculosis bovina, causada por Mycobacterium bovis (M. bovis), es endémica en la Argentina. Su presencia en el ganado bovino representa un riesgo para la salud humana debido a su carácter zoonótico, pudiendo además ...

    • Tuberculosis in swine co-infected with Mycobacterium avium subsp. hominissuis and Mycobacterium bovis in a cluster from Argentina 

      Barandiaran, Soledad; Pérez, Andrés M.; Gioffre, Andrea; Martinez Vivot, Marcela; Cataldi, Angel Adrian; Zumarraga, Martin Jose (Cambridge University Press, 2015-04)
      In Argentina little is known about the epidemiology of tuberculosis (TB) infection in swine. We characterized the epidemiological dynamics of Mycobacterium avium complex (MAC) infection in a swine population of Argentina ...