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Mostrando ítems 1-20 de 34
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A new piroplasmid species infecting dogs: morphological and molecular characterization and pathogeny of Babesia negevi n. sp.
Baneth, Gad; Nachum‑Biala, Yaarit; Birkenheuer, Adam Joseph; Schreeg, Megan Elizabeth; Prince, Hagar; Florin-Christensen, Monica; Schnittger, Leonhard; Aroch, Itamar (BMC, 2020-04)Introduction: Babesiosis is a protozoan tick-borne infection associated with anemia and life-threatening disease in humans, domestic and wildlife animals. Dogs are infected by at least six well-characterized Babesia spp. ... -
A novel type 1 cystatin involved in the regulation of Rhipicephalus microplus midgut cysteine proteases
Lu, Stephen; Rocha, Leticia A. da; Torquato, Ricardo J.S.; Vaz Junior, Itabajara da Silva; Florin-Christensen, Mónica; Tanaka, Aparecida S. (Elsevier, 2020-05)Rhipicephalus microplus is a cattle ectoparasite found in tropical and subtropical regions around the world with great impact on livestock production. R. microplus can also harbor pathogens, such as Babesia sp. and Anaplasma ... -
Aplicación de un método de extracción de ADN a partir de sangre canina sensible y de bajo costo para el diagnóstico molecular de Leishmania sp. = Application of a sensitive and low cost method for the extraction of DNA from canine blood to the molecular diagnosis of Leishmania sp.
Ascencio, Mariano; Florin-Christensen, Mónica; Schnittger, Leonhard; Rodriguez, Anabel Elisa (Universidad de Morón, 2017-10)La leishmaniosis canina (LC) es una enfermedad causada por hemoparásitos del género Leishmania. Los parásitos se transmiten a través de vectores flebótomos a los seres humanos y a otros mamíferos, generando cuadros ... -
Babesia microti immunoreactive rhoptry-associated protein-1 paralogs are ancestral members of the piroplasmid-confined RAP-1 family
Bastos, Reginaldo; Thekkiniath, Jose; Ben Mamoun, Choukri; Fuller, Lee; Molestina, Robert E.; Florin-Christensen, Mónica; Schnittger, Leonhard; Alzan, Heba F.; Suarez, Carlos (MDPI, 2021-11)Babesia, Cytauxzoon and Theileria are tick-borne apicomplexan parasites of the order Piroplasmida, responsible for diseases in humans and animals. Members of the piroplasmid rhoptry-associated protein-1 (pRAP-1) family ... -
Characterization of a Novel Thermostable Enzyme from Thermus sp. 2.9 with Phospholipase and Acyltransferase Activities
Navas, Laura Emilce; Florin-Christensen, Mónica; Benintende, Graciela Beatriz; Zandomeni, Ruben; Berretta, Marcelo Facundo (Karger, 2018)Phospholipases are classified in different enzyme families according to the ester bond they cleave within phospholipids. The use of phospholipases in industrial processes has prompted the search for new enzymes with ... -
Characterization of a papain-like cysteine protease essential for the survival of Babesia ovis merozoites
Carletti, Tamara; Mesplet, Maria; Mira, Anabela; Weir, William; Shiels, Brian; Gonzalez Oliva, Abel; Schnittger, Leonhard; Florin-Christensen, Mónica; Barreto, Carmo (2016)Babesia ovis, a tick-transmitted intraerythrocytic protozoan parasite, causes severe infections in small ruminants from Southern Europe, Middle East, and Northern Africa. With the aim of finding potential targets for the ... -
Comparative Degradome Analysis of the Bovine Piroplasmid Pathogens Babesia bovis and Theileria annulata
Poklepovich Caride, Tomás Javier; Mesplet, Maria; Gallenti, Romina Josefina; Florin-Christensen, Mónica; Schnittger, Leonhard (MDPI, 2023-02)Babesia bovis and Theileria annulata are tick-borne hemoprotozoans that impact bovine health and are responsible for considerable fatalities in tropical and subtropical regions around the world. Both pathogens infect the ... -
Cysteine proteinase C1A paralog profiles correspond with phylogenetic lineages of pathogenic piroplasmids
Ascencio, Mariano; Florin-Christensen, Mónica; Mamoun, Choukri B.; Weir, William; Shiels, Brian; Schnittger, Leonhard (MDPI, 2018-04)Piroplasmid parasites comprising of Babesia, Theileria, and Cytauxzoon are transmitted by ticks to farm and pet animals and have a significant impact on livestock industries and animal health in tropical and subtropical ... -
Degrade to survive : the intricate world of piroplasmid proteases
Florin-Christensen, Mónica; Sojka, Daniel; Ganzinelli, Sabrina Belen; Snebergerová, Pavla; Suarez, Carlos Esteban; Schnittger, Leonhard (Elsevier, 2023-07)Piroplasmids of the genera Babesia, Theileria, and Cytauxzoon are tick-transmitted parasites with a high impact on animals and humans. They have complex life cycles in their definitive arthropod and intermediate vertebrate ... -
Development of a loop-mediated isothermal amplification (LAMP) and a direct LAMP for the specific detection of Nosema ceranae, a parasite of honey bees
Lannutti, Lucas; Mira, Anabela; Basualdo, Marina; Rodriguez, Graciela Adriana; Erler, Silvio; Silva, Victoria Ayelén; Gisder, Sebastian; Genersch, Elke; Florin-Christensen, Mónica; Schnittger, Leonhard (Springer, 2020-10)Nosema ceranae is a ubiquitous microsporidian pathogen infecting the midgut of honey bees. The infection causes bee nosemosis, a disease associated with malnutrition, dysentery, and lethargic behavior, and results in ... -
Discovery of antigens and cellular mechanisms in the protozoan parasite sarcocystis aucheniae using immunoproteomics
Wieser, Sara Nathaly; Decker Franco, Cecilia; De Alba, Paloma; Romero, Sandra Raquel; Ferrari, Alejandro; Schnittger, Leonhard; Florin-Christensen, Monica (MDPI, 2023-12)Sarcocystis aucheniae is a coccidian parasite that produces macroscopic sarcocysts in South American camelid (SAC) muscles and causes a disease known as SAC sarcocystosis. This parasitosis hampers the commercialization of ... -
Evidence for extensive genetic diversity and substructuring of the Babesia bovis metapopulation
Flores, Daniela; Minichiello, Y.; Araujo, Flabio Ribeiro de; Shkap, V.; Benitez, Daniel Francisco; Echaide, Ignacio Eduardo; Rolls, P.; Mosqueda, J.; Pacheco, Maria Gabriela; Petterson, Maria Elizabeth; Florin-Christensen, Mónica; Schnittger, Leonhard (2013-11)Babesia bovis is a tick-transmitted haemoprotozoan and a causative agent of bovine babesiosis, a cattle disease that causes significant economic loss in tropical and subtropical regions. A panel of nineteen micro- and ... -
High genetic diversity and differentiation of the babesia ovis population in Turkey
Mira, Anabela; Unlu, Ahmet Hakan; Bilgic, Huseyin Bilgin; Bakirci, Serkan; Hacilarlioglu, Selin; Karagenc, Tulin; Carletti, Tamara; Weir, William; Shiels, Brian; Shkap, Varda; Aktas, Munir; Florin‐Christensen, Mónica; Schnittger, Leonhard (Wiley, 2020-07)Babesia ovis is a tick‐transmitted protozoan haemoparasite causing ovine babesiosis in sheep and goats leading to considerable economic loss in Turkey and neighbouring countries. There are no vaccines available, therapeutic ... -
Highly sensitive nested PCR and rapid immunochromatographic detection of Babesia bovis and Babesia bigemina infection in a cattle herd with acute clinical and fatal cases in Argentina
Ganzinelli, Sabrina Belen; Benitez, Daniel Francisco; Gantuya, Sambuu; Guswanto, Azirwan; Florin-Christensen, Mónica; Schnittger, Leonhard; Igarashi, Ikuo (Wiley, 2020-07)Bovine babesiosis is a tick‐transmitted haemoparasitic disease caused by Babesia bovis and B. bigemina affecting cattle of tropical and subtropical regions around the world. Pathogens are transmitted by the tick vector ... -
In silico identification of immunotherapeutic and diagnostic targets in the glycosylphosphatidylinositol metabolism of the coccidian Sarcocystis aucheniae
Decker Franco, Cecilia; Wieser, Sara Nathaly; Soria, Marcelo Abel; De Alba, Paloma; Florin-Christensen, Mónica; Schnittger, Leonhard (Wiley, 2020-07)Meat of the South American camelids (SACs) llama and alpaca is an important source of animal protein and income for rural families in the Andes, and a product with significant growth potential for local and international ... -
In Silico Survey and Characterization of Babesia microti Functional and Non-Functional Proteases
Florin-Christensen, Monica; Wieser, Sara Nathaly; Suarez, Carlos E.; Schnittger, Leonhard (MDPI, 2021-11)Human babesiosis caused by the intraerythrocytic apicomplexan Babesia microti is an expanding tick-borne zoonotic disease that may cause severe symptoms and death in elderly or immunocompromised individuals. In light of ... -
International interlaboratory validation of a nested PCR for molecular detection of Babesia bovis and Babesia bigemina, causative agents of bovine babesiosis
Ganzinelli, Sabrina Belen; Byaruhanga, Charles; Primo, María Evangelina; Lukanji, Zinathi; Sibeko, Kgomotso; Matjila, Tshepo; Neves, Luis; Benitez, Daniel Francisco; Enkhbaatar, Batmagnai; Nugraha, Arifin Budiman; Igarashi, Ikuo; Florin-Christensen, Mónica; Schnittger, Leonhard (Elsevier, 2022-04)Babesia bovis and B. bigemina are tick-transmitted parasites causing bovine babesiosis, characterized by significant morbidity and mortality leading to economic losses to the livestock industry in tropical and subtropical ... -
Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design
Lu, Stephen; Ascencio, Mariano; Torquato, Ricardo J.S.; Florin-Christensen, Mónica; Tanaka, Aparecida S. (Elsevier, 2020-12)C1A cysteine peptidases have been shown to play an important role during apicomplexan invasion and egress of host red blood cells (RBCs) and therefore have been exploited as targets for drug development, in which peptidase ... -
Molecular and serological detection of Babesia bovis- and Babesia bigemina-infection in bovines and water buffaloes raised jointly in an endemic field
Romero-Salas, Dora; Mira, Anabela; Mosqueda, Juan; García-Vázquez, Zeferino; Hidalgo-Ruiz, Mario; Ortiz Vela, Noot Aditya; Perez de Leóne, Adalberto Angel; Florin-Christensen, Monica; Schnittger, Leonhard (2016-01)Babesia bovis and Babesia bigemina are causative agents of bovine babesiosis, a tick-borne disease of cattle in tropical and subtropical regions. Babesia spp. infection adversely affects cattle health and can be fatal ... -
Molecular characterization of Cryptosporidium isolates from calves in Argentina
Tomazic, Mariela Luján; Maidana, Jimena; Dominguez, Mariana Gabriela; Louge Uriarte, Enrique Leopoldo; Galarza, Roxana Ivon; Garro, Carlos Javier; Florin-Christensen, Monica; Schnittger, Leonhard (2013-12)Cryptosporidiosis is responsible for significant fatalities of neonatal calves, resulting in substantial economic loss in dairy farming in several countries. Additionally, the high shedding of environmentally resistant ...