Mostrar el registro sencillo del ítem
resumen
Resumen
Introduction of influenza A viruses (FLUAV) into poultry from waterfowl is frequent, producing economic burden and increasing the probability of human infections. We have previously described the presence of FLUAV in wild birds in Argentina with unique evolutionary trajectories belonging to a South American lineage different from the North American and Eurasian lineages. Adaptability of this South American lineage FLUAV to poultry species is still poorly
[ver mas...]
dc.contributor.author | Ferreri, Lucas Matias | |
dc.contributor.author | Carnaccini, Silvia | |
dc.contributor.author | Olivera, Valeria Soledad | |
dc.contributor.author | Pereda, Ariel Julian | |
dc.contributor.author | Rajao, Daniela | |
dc.contributor.author | Perez, Daniel R. | |
dc.coverage.spatial | South America .......... (continent) (World) | es_AR |
dc.coverage.spatial | 1000002 | es_AR |
dc.date.accessioned | 2023-07-05T18:32:31Z | |
dc.date.available | 2023-07-05T18:32:31Z | |
dc.date.issued | 2023-05 | |
dc.identifier.issn | 2297-1769 | |
dc.identifier.other | https://doi.org/10.3389/fvets.2023.1182550 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12123/14704 | |
dc.identifier.uri | https://www.frontiersin.org/articles/10.3389/fvets.2023.1182550/full | |
dc.description.abstract | Introduction of influenza A viruses (FLUAV) into poultry from waterfowl is frequent, producing economic burden and increasing the probability of human infections. We have previously described the presence of FLUAV in wild birds in Argentina with unique evolutionary trajectories belonging to a South American lineage different from the North American and Eurasian lineages. Adaptability of this South American lineage FLUAV to poultry species is still poorly understood. In the present report, we evaluated the capacity of an H4N2 FLUAV from the South American lineage to adapt to chickens after low number of passages. We found that five mutations were acquired after five passages in 3-days-old chickens. These mutations produced a virus with better infectivity in ex vivo trachea explants but overall lower infection in lung explants. Infection of 3-week-old chickens persisted for a longer period and was detected in more tissues than the parental virus, suggesting adaptation of the H4N2 influenza A virus to chicken. | eng |
dc.format | application/pdf | es_AR |
dc.language.iso | eng | es_AR |
dc.publisher | Frontiers Media | es_AR |
dc.relation | info:eu-repograntAgreement/INTA/PNSA-1115052/AR./Epidemiología y desarrollo de estrategias para la prevención y control de enfermedades que afectan la salud pública, enfermedades exóticas y limitantes del comercio internacional. | es_AR |
dc.relation | info:eu-repograntAgreement/INTA/PNSA-1115056/AR./Enfermedades infecciosas de las aves. | es_AR |
dc.rights | info:eu-repo/semantics/openAccess | es_AR |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | es_AR |
dc.source | Frontiers in Veterinary Science 10 : 1182550. (May 2023) | es_AR |
dc.subject | Pollo | es_AR |
dc.subject | Chickens | eng |
dc.subject | Virus de la Influenza Aviar | es_AR |
dc.subject | Avian Influenzavirus | eng |
dc.subject | Poultry | eng |
dc.subject | Aves de Corral | es_AR |
dc.subject | Aves Acuáticas | es_AR |
dc.subject | Waterfowl | eng |
dc.subject | Enfermedades de los Animales | es_AR |
dc.subject | Animal Diseases | eng |
dc.subject | América del Sur | |
dc.subject | South America | eng |
dc.title | South American H4N2 influenza A virus improved replication in chicken trachea after low number of passages | es_AR |
dc.type | info:ar-repo/semantics/artículo | es_AR |
dc.type | info:eu-repo/semantics/article | es_AR |
dc.type | info:eu-repo/semantics/publishedVersion | es_AR |
dc.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | es_AR |
dc.description.origen | Instituto de Virología | es_AR |
dc.description.fil | Fil: Ferreri, Lucas. University of Georgia. College of Veterinary Medicine. Poultry Diagnostic and Research Center; Estados Unidos | es_AR |
dc.description.fil | Fil: Ferreri, Lucas. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina | es_AR |
dc.description.fil | Fil: Carnaccini, Silvia. University of Georgia. College of Veterinary Medicine. Poultry Diagnostic and Research Center; Estados Unidos | es_AR |
dc.description.fil | Fil: Olivera, Valeria Soledad. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina | es_AR |
dc.description.fil | Fil: Pereda, Ariel Julian. Instituto Nacional de Tecnología Agropecuaria (INTA). Programa Nacional Salud Animal; Argentina | es_AR |
dc.description.fil | Fil: Rajao, Daniela. University of Georgia. College of Veterinary Medicine. Poultry Diagnostic and Research Center; Estados Unidos | es_AR |
dc.description.fil | Fil: Perez, Daniel R. University of Georgia. College of Veterinary Medicine. Poultry Diagnostic and Research Center; Estados Unidos | es_AR |
dc.subtype | cientifico |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
common
-
Artículos científicos [199]