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Mostrando ítems 21-40 de 41
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Feasibility of polyclonal avian immunoglobulins (IgY) as prophylaxis against human norovirus infection
Artman, Chad; Idegwu, Nnebuefe; Brumfield, Kyle D.; Lai, Ken; Hauta, Shirley; Falzarano, Darryl; Parreño, Gladys Viviana; Yuan, Lijuan; Geyer, James D.; Goepp, Julius G. (MDPI, 2022-11)Background: Human norovirus (HuNoV) is the leading viral cause of diarrhea, with GII.4 as the predominant genotype of HuNoV outbreaks globally. However, new genogroup variants emerge periodically, complicating the development ... -
Human rotavirus replicates in salivary glands and primes immune responses in facial and intestinal lymphoid tissues of gnotobiotic pigs
Nyblade, Charlotte; Zhou, Peng; Frazier, Maggie; Frazier, Annie; Hensley, Casey; Fantasia-Davis, Ariana; Shahrudin, Shabihah; Hoffer, Miranda; Agbemabiese, Chantal Ama; LaRue, Lauren; Barro, Mario; Patton, John T.; Parreño, Gladys Viviana; Yuan, Lijuan (MDPI, 2023-08)Human rotavirus (HRV) is a leading cause of viral gastroenteritis in children across the globe. The virus has long been established as a pathogen of the gastrointestinal tract, targeting small intestine epithelial cells ... -
Integrated hepatitis e virus monitoring in central Argentina : a six-year analysis of clinical surveillance and wastewater-based epidemiology
Fantilli, Anabella Clara; Masachessi, Gisela; Di Cola, Guadalupe; Castro, Gonzalo; Sicilia, Paola; Marinzalda, María de los Angeles; Cachi, Ariana Mariela; Moreno, Claudia; Borda, Mariel; Ibarra, Gustavo; Rojas, Ricardo Manuel; Parreño, Gladys Viviana; Barbás, María Gabriela; Nates, Silvia Viviana; Pisano, María Belén; Ré, Viviana Elizabeth (Elsevier, 2024-09)Wastewater-based epidemiology (WBE) has gained prominence worldwide as a powerful tool in public health. This study aimed to monitor the circulation of Hepatitis E Virus (HEV) from wastewater samples collected during a ... -
Métodos matemáticos y modelos estadísticos aplicados a la estimación de la curva de dosis-respuesta en un estudio de exposición oral de cerdos gnotobióticos a Norovirus humano
Parreño, Gladys Viviana (Facultad de Agronomía, Universidad de Buenos Aires, 2021)Los modelos animales son utilizados en estudios pre-clínicos para reproducir las infecciones por patógenos humanos. En el proceso de estandarización de estos modelos resulta indispensable conocer cómo se producen la infección ... -
Molecular and antigenic characterization of bovine Coronavirus circulating in Argentinean cattle during 1994–2010
Bok, Marina; Miño, Samuel; Rodriguez, Daniela; Badaracco, Alejandra; Nuñes, I.; Souza, Sibele P.; Bilbao, G.; Louge Uriarte, Enrique Leopoldo; Galarza, Roxana Ivon; Vega, Celina Guadalupe; Odeon, Anselmo Carlos; Saif, LInda J.; Parreño, Gladys Viviana (Elsevier, 2015-12)Bovine coronavirus (BCoV) is an important viral pathogen associated with neonatal calf diarrhea. Our aim was to investigate the incidence of BCoV in diarrhea outbreaks in beef and dairy herds from Argentina during 1994–2010. ... -
Molecular characterization of equine rotavirus group A detected in Argentinean foals during 2009–2014
Miño, Samuel; Aduriz Guerrero, Matías; Barrandeguy, Maria Edith; Parreño, Viviana (2017-12)Equine rotavirus group A (RVA) has been detected in several countries worldwide since its first detection in 1975. Currently, equine RVA is considered the major cause of dehydrating diarrhea in foals younger than 3 months, ... -
Molecular characterization of group A rotavirus strains detected in alpacas (Vicugna pacos) from Peru
Badaracco, Alejandra; Cordero, Aida; Vega, Celina Guadalupe; Bok, Marina; Zeller, Mark; Heylen, Elisabeth; Fernández, Gonzalo; Díez-Baños, Pablo; Morrondo, Patrocinio; Guevara, Héctor; Matthijnssens, Jelle; Parreño, Gladys Viviana (Microbiology Society, 2021-04)The alpaca is a very important social and economic resource for the production of fibre and meat for Andean communities. Peru is the main producer of alpacas. Group A rotavirus (RVA) has been sporadically detected in ... -
Molecular detection of bovine Noroviruses in Argentinean dairy calves : circulation of a tentative new genotype
Ferragut, Fátima; Vega, Celina Guadalupe; Mauroy, Axel; Conceição-Neto, Nádia; Zeller, Mark; Heylen, Elisabeth; Louge Uriarte, Enrique Leopoldo; Bilbao, Gladys; Bok, Marina; Matthijnssens, Jelle; Thiry, Etienne; Badaracco, Alejandra; Parreño, Gladys Viviana (2016)Bovine noroviruses are enteric pathogens detected in fecal samples of both diarrheic and non-diarrheic calves from several countries worldwide. However, epidemiological information regarding bovine noroviruses is still ... -
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
Dalvie, Neil C.; Brady, Joseph R.; Crowell, Laura E.; Tracey, Mary Kate; Biedermann, Andrew M.; Kaur, Kawaljit; Hickey, John M.; Kristensen II, D. Lee; Bonnyman, Alexandra D.; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Bok, Marina; Vega, Celina Guadalupe; Mukhopadhyay, Tarit K.; Joshi, Sangeeta B.; Volkin, David B.; Parreño, Gladys; Love, Kerry R.; Love, J. Christopher (BMC, 2021-05)Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ... -
Novel viruses determined using fecal virome analysis in the feces of foals with diarrea
Vega, Celina Guadalupe; Conceição-Neto, Nádia; Miño, Samuel; Zeller, Mark; Heylen, Elisabeth; Parreño, Viviana; Barrandeguy, Maria Edith; Matthijnssens, Jelle (2016)This study aims to expand the knowledge of viral species present in feces of foals suffering diarrhea using Next Generation Sequencing. This will be useful to further explore the role of new infectious agents in this illness ... -
Occurrence of Cryptosporidium and other enteropathogens and their association with diarrhea in dairy calves of Buenos Aires province, Argentina
Garro, Carlos Javier; Morici, Gabriel Edgardo; Tomazic, Mariela Luján; Vilte, Daniel Alejandro; Encinas, Micaela; Vega, Celina Guadalupe; Bok, Marina; Parreño, Viviana; Schnittger, Leonhard (Elsevier, 2021-04)Cryptosporidiosis of neonatal dairy calves causes diarrhea, resulting in important economic losses. In Argentina, prevalence values of Cryptosporidium spp. and other enteropathogens such as group A rotavirus (RVA), bovine ... -
Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages
Miño, Samuel; Parreño, Viviana; Barrandeguy, Maria Edith (2016)The structural analyses revealed that the aa substitutions in VP7 are in the antigenic sites and in the VP7:VP6 interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving ... -
Prevalence and viability of group A rotavirus in dairy farm water sources
Castells, M.L.; Schild, Carlos Omar; Caffarena, Rubén Dario; Bok, Marina; Giannitti, Federico; Armendano, Joaquín Ignacio; Riet‐Correa, Franklin; Victoria, M.; Parreño, Viviana; Colina, Rodney (2018-03)Aim: To analyse group A rotavirus (RVA) environmental contamination in waters used for calves' consumption and to assess viral viability in dairy farm water sources. Methods and Results: We analysed 202 samples of water ... -
Prevención y tratamiento de Rotavirus A mediante nanoanticuerpos VHH anti-VP6
Maffey, Lucia (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2017-06)La diarrea asociada a Rotavirus A (RVA) representa una de las principales causas de mortalidad infantil a nivel mundial. Si bien la vacunación masiva contra RVA ha logrado disminuir significativamente las muertes causadas ... -
Probiotic as adjuvant significantly improves protection of the Lanzhou trivalent rotavirus vaccine against heterologous challenge in a gnotobiotic pig model of human rotavirus infection and disease
Parreño, Gladys Viviana; Bai, Muqun; Liu, Fangning; Jing, Jiqiang; Olney, Erika; Li, Guohua; Wen, Ke; Yang, Xingdong; Castellucc, Tammy Bui; Kocher, Jacob F.; Zhou, Xu; Yuan, Lijuan (MDPI, 2022-09)This preclinical study in the gnotobiotic (Gn) pig model of human rotavirus (HRV) infection and disease evaluates the effect of probiotic Lactobacillus rhamnosus GG (LGG) as a mucosal adjuvant on the immunogenicity and ... -
Quadruplex real-time TaqMan® RT-qPCR assay for differentiation of equine group A and B rotaviruses and Identification of group A G3 and G14 genotypes
Carossino, Mariano; Balasuriya, Udeni B.R.; Thieulent, Côme J.; Barrandeguy, Maria Edith; Vissani, Maria Aldana; Parreño, Gladys Viviana (MDPI, 2023-07)Equine rotavirus A (ERVA) is the leading cause of diarrhea in foals, with G3P[12] and G14P[12] genotypes being the most prevalent. Recently, equine G3-like RVA was recognized as an emerging infection in children, and a ... -
Relevamiento serológico de anticuerpos contra enfermedades virales de interés sanitario en llamas (Lama glama) de la provincia de Jujuy, Argentina = Serological survey of antibodies against viral diseases of public health interest in llamas (Lama glama) from Jujuy province, Argentina
Barbieri, Elena Susana; Rodriguez, Daniela Vanesa; Marín, Raúl E.; Setti, Walter Eduardo; Romero, Sandra Raquel; Barrandeguy, Maria Edith; Parreño, Gladys Viviana (Asociación Argentina de Microbiología, 2014-03)Las poblaciones de llamas de Argentina se concentran principalmente en la provincia de Jujuy; su explotación representa un importante recurso económico de las comunidades altoandinas. El objetivo de este trabajo fue evaluar ... -
SARS-CoV-2 specific nanobodies neutralize different variants of concern and reduce virus load in the brain of h-ACE2 transgenic mice
Pavan, Florencia; Bok, Marina; Betanzos San Juan, Rafael; Malito, Juan Pablo; Marcoppido, Gisela Ariana; Franco, Diego Rafael; Militelo, Daniela Ayelen; Schammas, Juan Manuel; Bari, Sara Elizabeth; Stone, William B.; López, Krisangel; Porier, Danielle LaBrie; Muller, John Anthony; Auguste, Albert J.; Yuan, Lijuan; Wigdorovitz, Andres; Parreño, Gladys Viviana; Ibañez, Lorena Itat (MDPI, 2024-02)Since the beginning of the COVID-19 pandemic, there has been a significant need to develop antivirals and vaccines to combat the disease. In this work, we developed llama-derived nanobodies (Nbs) directed against the ... -
Serological responses of Guinea pigs and heifers to eight different BoAHV-1 vaccine formulations
Camargo, Luana; Franklin, Yasmin Vieira; da Silva, Gustavo Feliciano Resende; Santos, Janaína Ferreira; Parreño, Gladys Viviana; Wigdorovitz, Andres; Gomes, Viviani (MDPI, 2024-06)Bovine alphaherpesvirus 1 (BoAHV-1) infection affects the production and reproductive performance of dairy and beef livestock, resulting in considerable economic losses. In addition to biosecurity measures, vaccination ... -
Síndrome diarreico en potrillos, diagnóstico y caracterización de los agentes virales involucrados
Miño, Samuel (Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2017-08)Las diarreas neonatales representan uno de los síndromes clínicos más relevantes y frecuentes en potrillos menores de 6 meses de edad. Rotavirus grupo A (RVA) es el principal agente viral asociado a diarreas en potrillos, ...