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Mostrando ítems 1-18 de 18

    • Characterization of Escherichia coli carrying mcr-1-plasmids recovered from food animals from Argentina 

      Dominguez, Johana Elizabeth; Faccone, Diego; Tijet, Nathalie; Gomez, Sonia; Corso, Alejandra; Fernandez Miyakawa, Mariano Enrique; Melano, Roberto G. (Frontiers Media, 2019-03)
      In this study, we found mcr-1.1 and mcr-1.5 genes carried by IncI2 plasmids in a subset of Escherichia coli isolates recovered from commercial broiler farms in Argentina. The comparative analysis of the sequences of these ...

    • Clostridium perfringens epsilon toxin induces permanent neuronal degeneration and behavioral changes 

      Morris, Winston Eduardo; Goldstein, Jorge; Redondo, Leandro Martí­n; Cangelosi, Adriana; Geoghegan, Patricia; Brocco, Marcela Adriana; Loidl, Fabián C.; Fernandez Miyakawa, Mariano Enrique (2017-05)
      Clostridium perfringens epsilon toxin (ETX), the most potent toxin produced by this bacteria, plays a key role in the pathogenesis of enterotoxaemia in ruminants, causing brain edema and encephalomalacia. Studies of animals ...

    • Clostridium perfringens type E virulence traits involved in gut colonization 

      Redondo, Leandro Martín; Diaz Carrasco, Juan María; Redondo, Enzo Alejandro; Delgado, Fernando Oscar; Fernandez Miyakawa, Mariano Enrique (PLOS, 2015-03-23)
      Clostridium perfringens type E disease in ruminants has been characterized by hemorrhagic enteritis or sudden death. Although type E isolates are defined by the production of alpha and iota toxin, little is known about the ...

    • Early events of enterotoxigenic Escherichia coli colonization on gut barrier function : no longer undETECted? 

      Diaz Carrasco, Juan Marí­a; Fernandez Miyakawa, Mariano Enrique (2017)

    • Effects of a blend of chestnut and quebracho tannins on gut health and performance of broiler chickens 

      Redondo, Enzo Alejandro; Redondo, Leandro Martin; Bruzzone, Octavio Augusto; Diaz Carrasco, Juan Maria; Cabral, Claudio; Garces, Victorino M.; Liñeiro, Maximo M.; Fernandez Miyakawa, Mariano Enrique (Plos ONE, 2022-01)
      Antimicrobial restrictions prompted the search for cost and biologically effective alternatives to replace antimicrobial growth promoters (AGPs) in food-producing animals. In addition, the efficacy of this alternatives ...

    • Effects of Clostridium perfringens iota toxin in the small intestine of mice 

      Redondo, Leandro Martin; Redondo, Enzo Alejandro; Dailoff, Gabriela Cecilia; Leiva, Carlos; Diaz Carrasco, Juan Maria; Bruzzone, Octavio Augusto; Cangelosi, Adriana; Geoghegan, Patricia; Fernandez Miyakawa, Mariano Enrique (2017-12)
      Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme. As type E causes hemorrhagic enteritis in cattle, it ...

    • Efficacy of chestnut and quebracho wood extracts to control Salmonella in poultry 

      Casanova, Natalia Alejandra; Redondo, Leandro Martin; Redondo, Enzo Alejandro; Joaquim, Patricia Estefania; Dominguez, Johana Natali; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (Wiley, 2021-07)
      Aims: The study was aimed to evaluate the antibacterial activity and efficacy of chestnut and quebracho wood extracts against Salmonella by in vitro assays and in vivo trials. Methods and results: The extracts showed ...

    • An experimental reproduction of necrotic enteritis In broiler chickens 

      Redondo, Leandro Martí­n; Redondo, Enzo Alejandro; Delgado, Fernando Oscar; La Sala, Luciano Francisco; Fernandez Miyakawa, Mariano Enrique (2016)
      Clostridium perfringens is the main causative agent of avian necrotic enteritis (NE), an enteric infectious disease considered among the most important diseases in the poultry industry. Currently, there are numerous reports ...

    • IgY-based antivenom against Bothrops alternatus: Production and neutralization efficacy 

      Leiva, Carlos Leónidas; Cangelosi, Adriana; Mariconda, Virginia; Farace, Mariano; Geoghegan, Patricia; Brero, Luisa; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo Anibal (Elsevier, 2019-05)
      Antivenom for the treatment of bothropic snakebite is a priority for public health institutions from Latin America. An alternative to the conventional antivenom production is based on the use of egg yolk antibodies – ...

    • Impact of chestnut and quebracho tannins on rumen microbiota of bovines 

      Diaz Carrasco, Juan María; Cabral, Claudio; Redondo, Leandro Martín; Pin Viso, Natalia Daniela; Colombatto, Darío; Farber, Marisa Diana; Fernandez Miyakawa, Mariano Enrique (Hindawi, 2017)
      The use of phytogenic dietary additives is being evaluated as a means to improve animal productivity. The effect of tannins seems to be the influence not only directly on the digestive process through binding of dietary ...

    • Necrotic Enteritis in Young Calves 

      Morris, Winston Eduardo; Venzano, Agustin Jose; Elizondo, Ana Maria; Vilte, Daniel Alejandro; Mercado, Elsa Cristina; Fernandez Miyakawa, Mariano Enrique (Sage Publishing, 2011-03)
      Non–enterotoxin (CPE)–producing Clostridium perfringens type A has been associated with enteritis in calves. Recent evidence has suggested that a novel toxin, named beta2 (CPB2), is implicated in the pathogenesis of this ...

    • Overview of the role of Shiga toxins in porcine edema disease pathogenesis 

      Casanova, Natalia Andrea; Redondo, Leandro Martin; Dailoff, Gabriela Cecilia; Arenas, David; Fernandez Miyakawa, Mariano Enrique (Elsevier, 2018-06)
      Shiga toxin-producing Escherichia coli (STEC) have been implicated as the cause of enterotoxemias, such as hemolytic uremic syndrome in humans and edema disease (ED) of pigs. Stx1 and Stx2 are the most common types found ...

    • Phytochemicals as antibiotic alternatives to promote growth and enhance host health 

      Lillehoj, Hyun; Yanhong, Liu; Calsamiglia, Sergio; Fernandez Miyakawa, Mariano Enrique; Fang, Chi; Cravens, Ron L.; Oh, Sungtaek; Gay, Cyril G. (BioMed Central, 2018-07)
      There are heightened concerns globally on emerging drug-resistant superbugs and the lack of new antibiotics for treating human and animal diseases. For the agricultural industry, there is an urgent need to develop strategies ...

    • Rats as sources of multidrug-resistant Enterobacteriaceae in animal production environments 

      Dominguez, Johanna Elizabeth; Lovera, Rosario; Sánchez, Juliana; Redondo, Leandro Martin; Chacana, Pablo; Cavia, Regino; Fernandez Miyakawa, Mariano Enrique (Wiley, 2023-07)
      Rattus norvegicus and Rattus rattus are commensal pest rodents, considered reservoirs and vectors of zoonotic pathogens. In livestock farms, the wide use of antimicrobials and their release into the environment lead to ...

    • Simultaneous carriage of mcr-1 and other antimicrobial resistance determinants in Escherichia coli from poultry 

      Dominguez, Johanna Elizabeth; Redondo, Leandro Martín; Figueroa Espinosa, Roque A.; Cejas, Daniela; Gutkind, Gabriel Omar; Chacana, Pablo; Di Conza, José Alejandro; Fernandez Miyakawa, Mariano Enrique (Frontiers Media, 2018-07)
      The use of antimicrobial growth promoters (AGPs) in sub-therapeutic doses for long periods promotes the selection of resistant microorganisms and the subsequent risk of spreading this resistance to the human population and ...

    • Study of antioxidant capacity and metabolization of quebracho and chestnut tannins through in vitro gastrointestinal digestion-fermentation 

      Molino, Silvia; Fernandez Miyakawa, Mariano Enrique; Giovando, Samuele; Rufián Henares, José Ángel (Elsevier, 2018-10)
      Quebracho (QUE) and chestnut (CHE) are natural sources of tannins, but there are no connection between QUE, CHE and human health. The study investigated the antioxidant response and metabolization of tannin extracts trough ...

    • Tannins and bacitracin differentially modulate gut microbiota of broiler chickens 

      Diaz Carrasco, Juan Maria; Redondo, Enzo Alejandro; Pin Viso, Natalia Daniela; Redondo, Leandro Martin; Farber, Marisa Diana; Fernandez Miyakawa, Mariano Enrique (2018-02)
      Antibiotic growth promoters have been used for decades in poultry farming as a tool to maintain bird health and improve growth performance. Global concern about the recurrent emergence and spreading of antimicrobial ...

    • Use of adjuvant ISA VG 71 to produce neutralizing egg yolk antibodies against bothropic venom 

      Leiva, Carlos Leónidas; Cangelosi, Adriana; Mariconda, Virginia; Celi Castillo, Ana Beatriz; Joaquim, Patricia Estefania; Geoghegan, Patricia; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (Springer, 2023-02)
      The use of egg yolk antibodies—IgY technology—represents an alternative to the production of mammalian immunoglobulins and has several advantages regarding animal welfare and lower costs of production. The use of adjuvants ...