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Characterization of a Nanovaccine Platform Based on an α1,2- Mannobiose Derivative Shows Species-non-specific Targeting to Human, Bovine, Mouse, and Teleost Fish Dendritic Cells
Pappalardo, Juan Sebastián; Salmaso, Stefano; Levchenko, Tatyana S.; Mastrotto, Francesca; Bersani, Sara; Vermeulen, Monica; Ghersa, Federica; Quattrocchi, Valeria; Zamorano, Patricia Ines; Hartner, William C.; Toniutti, Micaela; Musacchio, Tiziana; Torchilin, Vladimir P. (ACS Publications, 2021-07)Dendritic cells serve as the main immune cells that trigger the immune response. We developed a simple and cost-effective nanovaccine platform based on the α1′,2-mannobiose derivative for dendritic cell targeting. In ... -
Effects of polydopamine-passivation on the optical properties of carbon dots and its potential use in vivo
Pappalardo, Juan Sebastián; Macairan, Jun-Ray; Macina, Alexia; Poulhazan, Alexandre; Quattrocchi, Valeria; Marcotte, Isabelle; Naccache, Rafik (Royal Society of Chemistry, 2020-07)Passivation of carbon dots via heteroatom doping has been shown to enhance their optical properties and tune their fluorescence signature. Additionally, the incorporation of polymeric precursors in carbon dot synthesis has ... -
Interaction between natural magnetite sub-micrometric particles and the Fasciola hepatica egg: the role of the exposed surface area
Raineri, Mariana; Lima Jr., Enio; Larroza, Marcela Patricia; Moreno, Mario Sergio; Vásquez Mansilla, Marcelo; Pappalardo, Juan Sebastián; Zysler, Roberto Daniel (Elsevier, 2019)Fasciolosis is a zoonotic world widely distributed disease caused by the liver fluke Fasciola hepatica, which affects animals and occasionally humans. On the other hand, natural iron oxide particles like magnetite are ...