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Eprinomectin accumulation in Rhipicephalus (Boophilus) microplus : pharmacokinetic and efficacy assessment
Lifschitz, Adrian Luis; Nava, Santiago; Mangold, Atilio Jose; Imperiale, Fernanda Andrea; Ballent, Mariana; Canevari, Jose Tobias; Lanusse, Carlos Edmundo (2016-01)Eprinomectin (EPM) is a macrocyclic lactone used against endo-ectoparasites without withdrawal time in milk and meat after its pour-on administration at 0.5 mg/kg. Previous experiments evaluated the efficacy of EPM against ... -
Influence of the cattle body weight estimation for drug dosing on the pharmacokinetic and efficacy of ivermectin against Rhipicephalus (Boophilus) microplus
Miro, Maria Victoria; Sarli, Macarena; Rossner, Maria Victoria; Gomez, Viviana Daniela; Toffaletti, Jose Rodolfo; Lifschitz, Adrian Luis; Nava, Santiago (Systematic and Applied Acarology Society, 2022-08)This study aimed to evaluate how the method of body weight estimation of a herd (average vs individual) for drug dosing may affect the pharmacokinetics and therapeutic efficacy of ivermectin 3.15% against Rhipicephalus ... -
Macrocyclic lactones and ectoparasites control in livestock: efficacy, drug resistance and therapeutic challenges
Lifschitz, Adrian Luis; Nava, Santiago; Miró, María Victoria; Canton, Candela; Alvarez, L.; Lanusse, Carlos Edmundo (Elsevier, 2024-08)Macrocyclic lactones (MLs) are the cornerstone of parasite control in livestock due to their broad-spectrum activity against endo (nematodes) and ecto (lice, ticks, mites) parasites. These molecules, introduced into the ... -
Relationship between pharmacokinetics of ivermectin (3.15%) and its efficacy to control the infestation with the tick Rhipicephalus (Boophilus) microplus in cattle
Nava, Santiago; Rossner, Maria Victoria; Ballent, Mariana; Mangold, Atilio Jose; Lanusse, Carlos Edmundo; Lifschitz, Adrian Luis (Elsevier, 2019-04)This study aimed to determine the relationship between the variation in plasma concentration of ivermectin 3.15% over time and its efficacy against the cattle tick Rhipicephalus (Boophilus) microplus. In addition, a trial ... -
Successive treatments with ivermectin (3.15%) to control the tick Rhipicephalus (Boophilus) microplus in cattle: Pharmacokinetic and efficacy assessment
Sarli, Macarena; Miró, Maria Victoria; Rossner, Maria Victoria; Nava, Santiago; Lifschitz, Adrian Luis (Elsevier, 2022-01)This study aimed to evaluate the pharmacokinetics, the potential accumulation in the body of treated animals and the efficacy of ivermectin long-acting formulation (3.15%) against the cattle tick Rhipicephalus (Boophilus) ...