• A tomato tocopherol-binding protein sheds light on intracellular a-tocopherol metabolism in plants 

      Bermudez Salazar, Luisa; del Pozo, Talía; Lira, Bruno Silvestre; Godoy, Fabiana de; Boos, Irene; Romano, Cecilia; Previtali, Viola; Almeida, Juliana; Brehelin, Claire; Asis, Ramón; Quadrana, Leandro Daniel; Demarco, Diego; Alseekh, Saleh; Salinas Gamboa, Rigel; Perez-Flores, Laura; Dominguez, Pia Guadalupe; Rothan, Christophe; Fernie, Alisdair R.; Gonzalez, Maurıcio; Stocker, Achim; Hemmerle, Andreas; Clausen, Mads Hartving; Carrari, Fernando; Rossi, Magdalena (Oxford University Press, 2018-11)
      Tocopherols are non-polar compounds synthesized in the plastids, which function as major antioxidants of the plant cells and are essential in the human diet. Both the intermediates and final products of the tocopherol ...
    • Identification of four novel DC-SIGN ligands on Mycobacterium bovis BCG 

      Carroll, Maria V.; Sim, Robert B.; Bigi, Fabiana; Jäkel, Anne; Antrobus, Robin; Mitchell, Daniel A. (Springer, 2010-09)
      Dendritic-cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN; CD209) has an important role in mediating adherence of Mycobacteria species, including M. tuberculosis and M. bovis BCG to human ...
    • In vivo subcellular localization of Mal de Río Cuarto virus (MRCV) non-structural proteins in insect cells reveals their putative functions 

      Maroniche, Guillermo Andrés; Mongelli, Vanesa Claudia; Llauger, Gabriela; Alfonso, Victoria; Taboga, Oscar Alberto; Del Vas, Mariana (Elsevier, 2012-09)
      The in vivo subcellular localization of Mal de Río Cuarto virus (MRCV, Fijivirus, Reoviridae) non-structural proteins fused to GFP was analyzed by confocal microscopy. P5-1 showed a cytoplasmic vesicular-like distribution ...
    • Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein 

      Carballeda, Juan Manuel; Maroniche, Guillermo Andrés; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (Elsevier, 2015-09)
      Infectious Bursal Disease Virus (IBDV) causes a highly relevant poultry disease that affects young chickens causing, among other effects, immunosuppression. IBDV is a bi-segmented double stranded RNA virus. The smaller ORF ...
    • Mycobacterial MCE proteins as transporters that control lipid homeostasis of the cell wall 

      Klepp, Laura Ines; Sabio Y Garcia, Julia Veronica; Bigi, Fabiana (Elsevier, 2022-01)
      Mammalian cell entry (mce) genes are not only present in genomes of pathogenic mycobacteria, including Mycobacterium tuberculosis (the causative agent of tuberculosis), but also in saprophytic and opportunistic mycobacterial ...
    • Novel Effector Protein EspY3 of Type III Secretion System from Enterohemorrhagic Escherichia coli Is Localized in Actin Pedestals 

      Larzabal, Mariano; Marques Da Silva, Wanderson; Riviere, Nahuel Agustín; Cataldi, Angel Adrian (MDPI AG, 2018)
      Enterohemorrhagic Escherichia coli (EHEC) and enteropathogenic Escherichia coli (EPEC) are attaching and effacing (A/E) pathogens, which translocate effector proteins to intestinal enterocytes through a type III secretion ...
    • Rapid and cost-effective process based on insect larvae for scale-up production of SARS-COV-2 spike protein for serological COVID-19 testing 

      Smith, Ignacio; Mc Callum, Gregorio Juan; Sabljic, Adriana Victoria; Marfia, Juan Ignacio; Bombicino, Silvina Sonia; Trabucchi, Aldana; Iacono, Ruben Francisco; Birenbaum, Joaquín Manuel; Vazquez, Susana Claudia; Minoia, Juan Mauricio; Cascone, Osvaldo; Lopez, Maria Gabriela; Taboga, Oscar Alberto; Targovnik, Alexandra Marisa; Wolman, Federico Javier; Fingermann, Matías; Alonso, Leonardo Gabriel; Valdez, Silvina Noemí; Miranda, María Victoria (Wiley, 2021-10)
      Serology testing for COVID-19 is important in evaluating active immune response against SARS-CoV-2, studying the antibody kinetics, and monitoring reinfections with genetic variants and new virus strains, in particular, ...
    • Study of the in vivo role of Mce2R, the transcriptional regulator of mce2 operon in Mycobacterium tuberculosis 

      Forrellad, Marina Andrea; Bianco, María Veronica; Blanco, Federico Carlos; Nuñez, Javier; Klepp, Laura Ines; Vazquez, Cristina Lourdes; Santangelo, María De La Paz; Rocha, Rosana Valeria; Soria, Marcelo; Golby, Paul; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (BMC, 2013-09)
      Background: Tuberculosis is one of the leading causes of mortality throughout the world. Mycobacterium tuberculosis, the agent of human tuberculosis, has developed strategies involving proteins and other compounds called ...
    • The P0 protein encoded by cotton leafroll dwarf virus (CLRDV) inhibits local but not systemic RNA silencing 

      Delfosse, Veronica Cecilia; Agrofoglio, Yamila Carla; Casse, Maria Florencia; Bonacic Kresic, Iván; Hopp, Horacio Esteban; Ziegler-Graff, Véronique; Distefano, Ana Julia (2014-02)
      Plants employ RNA silencing as a natural defense mechanism against viruses. As a counter-defense, viruses encode silencing suppressor proteins (SSPs) that suppress RNA silencing. Most, but not all, the P0 proteins encoded ...