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    • FasR regulates fatty acid biosynthesis and is essential for virulence of Mycobacterium tuberculosis 

      Mondino, Sonia; Vazquez, Cristina Lourdes; Cabruja, Matias; Sala, Claudia; Cazenave-Gassiot, Amaury; Blanco, Federico Carlos; Wenk, Markus R.; Bigi, Fabiana; Cole, Stewart T.; Gramajo, Hugo; Gago, Gabriela (Frontiers Media, 2020-10)
      Mycobacterium tuberculosis, the etiologic agent of human tuberculosis, is the world’s leading cause of death from an infectious disease. One of the main features of this pathogen is the complex and dynamic lipid composition ...

    • Metabolic profile of mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis 

      Santangelo, María De La Paz; Heuberger, Adam; Blanco, Federico Carlos; Forrellad, Marina Andrea; Taibo, Catalina Beatriz; Klepp, Laura Ines; Sabio y Garcia, Julia Veronica; Nikel, Pablo I.; Jackson, Mary; Bigi, Fabiana (2016)
      Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins ...

    • Mycobacterial MCE proteins as transporters that control lipid homeostasis of the cell wall 

      Klepp, Laura Ines; Sabio Y Garcia, Julia Veronica; Bigi, Fabiana (Elsevier, 2022-01)
      Mammalian cell entry (mce) genes are not only present in genomes of pathogenic mycobacteria, including Mycobacterium tuberculosis (the causative agent of tuberculosis), but also in saprophytic and opportunistic mycobacterial ...

    • Snakin/GASA proteins : involvement in hormone crosstalk and redox homeostasis 

      Nahirñak, Vanesa; Almasia, Natalia Ines; Hopp, Horacio Esteban; Vazquez Rovere, Cecilia (Taylor & Francis, 2012)
      Snakin/GASA proteins are widely distributed among plant species. They are expressed in different plant organs with high tissue and temporal specificity, and their subcellular localization varies among the different members. ...