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    • Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles 

      Bigi, María Mercedes; Vazquez, Cristina Lourdes; Castelão, Ana Beatriz C.; Garcia, Elizabeth Andrea; Cataldi, Angel Adrian; Jackson, Mary; McNeil, Michael; Soria, Marcelo Abel; Zumarraga, Martin Jose; Cabruja, Matias; Gago, Gabriela; Blanco, Federico Carlos; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Araujo, Flabio Ribeiro de; Bigi, Fabiana (Elsevier, 2019-12)
      Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic ...

    • Ancient Human Mitogenome of the Beagle Channel (Tierra del Fuego): An Argentine Collaborative Project 

      Arencibia, Valeria; Muñoz Hidalgo, Marianne Graziel; Crespo, Cristian; Maldonado, Lucas; Lichtenstein, Gabriel; Kamenetzky, Laura; Vera, Pablo Alfredo; Zangrando, Atilio F.; Tessone, Augusto; Avena, Sergio; Lia, Veronica Viviana; Puebla, Andrea Fabiana; Dejean, Cristina (Cambridge University Press, 2023-05)
      The increasing use of massively parallel sequencing in the study of current and ancient human populations has enabled new approaches to bioanthropological and archaeological issues; however, its application to archaeological ...

    • Characterization of two GH5 endoglucanases from termite microbiome using synthetic metagenomics 

      Ben Guerrero, Emiliano; Marrero Diaz De Villegas, Ruben; Soria, Marcelo Abel; Santangelo, María De La Paz; Campos, Eleonora; Talia, Paola Mónica (Springer, 2020-08)
      Here, we characterize two novel GH5 endoglucanases (GH5CelA and GH5CelB) from an uncultured bacterium identified in termite gut microbiomes. Both genes were codon-optimized, synthetized, cloned, and expressed as recombinant ...

    • Coupling virus-induced gene silencing to exogenous green fluorescence protein expression provides a highly efficient system for functional genomics in arabidopsis and across all stages of tomato fruit development 

      Quadrana, Leandro Daniel; Rodriguez, Maria Cecilia; Bermudez Salazar, Luisa; Nunes Nesi, Adriano; Fernie, Alisdair R.; Descalzo, Adriana Maria; Asis, Ramón; Rossi, Magdalena; Asurmendi, Sebastian; Carrari, Fernando (2011-07)
      Since the advent of the postgenomic era, efforts have focused on the development of rapid strategies for annotating plant genes of unknown function. Given its simplicity and rapidity, virus-induced gene silencing (VIGS) ...

    • CRISPR/Cas9 and genetic screens in malaria parasites : small genomes, big impact 

      Ishizaki, Takahiro; Hernandez, Sophia; Paoletta, Martina; Sanderson, Theo; Bushell, Ellen S. C. (Portland Press, 2022-06)
      The ∼30 Mb genomes of the Plasmodium parasites that cause malaria each encode ∼5000 genes, but the functions of the majority remain unknown. This is due to a paucity of functional annotation from sequence homology, which ...

    • Draft genome sequence data of Cercospora kikuchii, a causal agent of Cercospora leaf blight and purple seed stain of soybeans 

      Sautua, Francisco José; Gonzalez, Sergio Alberto; Doyle, Vinson P.; Berretta, Marcelo Facundo; Gordó, Manuela; Scandiani, María Mercedes; Rivarola, Maximo Lisandro; Fernandez, Paula Del Carmen; Carmona, Marcelo Anibal (Elsevier, 2019-10)
      Cercospora kikuchii (Tak. Matsumoto & Tomoy.) M.W. Gardner 1927 is an ascomycete fungal pathogen that causes Cercospora leaf blight and purple seed stain on soybean. Here, we report the first draft genome sequence and ...

    • Draft genome sequence of Mycobacterium bovis 04-303, a highly virulent strain from Argentina 

      Nishibe, Christiane; Canevari Castelão, Ana Beatriz; Dalla Costa, Ricardo; Pinto, Beatriz Jeronimo; Varuzza, Leonardo; Cataldi, Angel Adrian; Bernardelli, Amelia; Bigi, Fabiana; Blanco, Federico Carlos; Zumarraga, Martin Jose; Almeida, Nalvo Franco; Araujo, Flabio Ribeiro de (American Society for Microbiology, 2013-11)
      Mycobacterium bovis strain 04-303 was isolated from a wild boar living in a free-ranging field in Argentina. This work reports the draft genome sequence of this highly virulent strain and the genomic comparison of its major ...

    • Draft genome sequences of two mycobacterium bovis strains isolated from beef cattle in Paraguay 

      Sanabria, Lidia; Lagrave, Lorena; Nishibe, Christiane; Ribas, Augusto C.A.; Zumarraga, Martin Jose; Almeida, Nalvo Franco; Araujo, Flabio Ribeiro de (2017-07)
      This work reports the draft genome sequences of the Mycobacterium bovis strains M1009 and M1010, isolated from the lymph nodes of two infected cows on a beef farm in Paraguay. Comparative genomics between these strains and ...

    • First Genome Sequence of Leptospira interrogans Serovar Pomona, Isolated from a Bovine Abortion 

      Varni, Vanina Delia; Koval, Ariel; Nagel, Ariel Gaston; Ruybal, Paula; Caimi, Karina Cynthia; Amadio, Ariel F. (2016)
      Leptospirosis is a widespread zoonosis and a re-emergent disease of global distribution with major relevance in veterinary pro- duction. Here, we report the whole-genome sequence of Leptospira interrogans serovar Pomona ...

    • From lignocellulosic metagenomes to lignocellulolytic genes : trends, challenges and future prospects 

      Batista-García, Ramón Alberto; Sanchez-Carbente, María del Rayo; Talia, Paola Mónica; Jackson, Stephen A.; O'Leary, Niall D.; Dobson, Alan D. W.; Folch-Mallol, Jorge Luis (2016)
      Lignocellulose is the most abundant biomass on Earth with immense potential to act as a primary resource for the production of a range of compounds currently obtained from fossil fuel sources. However, lignocellulosic ...

    • Genome-wide association studies in sunflower : towards sclerotinia sclerotiorum and diaporthe/phomopsis resistance breeding 

      Filippi, Carla Valeria; Corro Molas, Andres Ezequiel; Dominguez, Matías; Colombo, Denis Nahuel; Heinz, Nicolás; Troglia, Carolina Beatriz; Maringolo, Carla Andrea; Quiroz, Facundo Jose; Alvarez, Daniel; Lia, Veronica Viviana; Paniego, Norma Beatriz (MDPI, 2022-12)
      Diseases caused by necrotrophic fungi, such as the cosmopolitan Sclerotinia sclerotiorum and the Diaporthe/Phomopsis complex, are among the most destructive diseases of sunflower worldwide. The lack of complete resistance ...

    • Genome-wide data (ChIP-seq) enabled identification of cell wall-related and aquaporin genes as targets of tomato ASR1, a drought stress-responsive transcription factor 

      Ricardi, Martiniano María; González, Rodrigo Matías; Silin, Zhong; Dominguez, Pia Guadalupe; Duffy, Tomas; Turjanski, Pablo Guillermo; Salgado Salter, Juan David; Alleva, Karina Edith; Carrari, Fernando; Giovannoni, James J.; Estevez, Jose Manuel; Iusem, Norberto Daniel (BMC, 2014-01)
      Background: Identifying the target genes of transcription factors is important for unraveling regulatory networks in all types of organisms. Our interest was precisely to uncover the spectrum of loci regulated by a widespread ...

    • K-mer counting and curated libraries drive efficient annotation of repeats in plant genomes 

      Contreras-Moreira, Bruno; Filippi, Carla Valeria; Naamati, Guy; García Girón, Carlos; Allen, James E.; Flicek, Paul (Wiley, 2021-09)
      The annotation of repetitive sequences within plant genomes can help in the interpretation of observed phenotypes. Moreover, repeat masking is required for tasks such as whole-genome alignment, promoter analysis, or pangenome ...

    • Pre-columbian mycobacterial genomes reveal seals as a source of new world human tuberculosis 

      Bos, Kirsten I.; Harkins, Kelly M.; Herbig, Alexander; Coscolla, Mireia; Weber, Nico; Comas, Iñaki; Forrest, Stephen A.; Bryant, Josephine M.; Harris, Simon R.; Schuenemann, Verena J.; Campbell, Tessa J.; Majander, Kerrtu; Wilbur, Alicia K.; Guichon, Ricardo A.; Steadman, Dawnie L. Wolfe; Cook, Della Collins; Niemann, Stefan; Behr, Marcel A.; Zumarraga, Martin Jose; Bastida, Ricardo; Huson, Daniel; Nieselt, Kay; Young, Douglas; Parkhill, Julian; Buikstra, Jane E.; Gagneux, Sebastien; Stone, Anne C.; Krause, Johannes (Springer Nature, 2014-08)
      Modern strains of Mycobacterium tuberculosis from the Americas are closely related to those from Europe, supporting the assumption that human tuberculosis was introduced post-contact1. This notion, however, is incompatible ...

    • Preparation of a working seed lot of BCG and quality control by PCR genotyping 

      Trovero, A.; Argüelles, Claudia; Cataldi, Angel Adrian (Asociación Argentina de Microbiología, 2010-04)
      The bacillus Calmette-Guérin (BCG) was obtained in 1920 after successive passages leading to the attenuation of a Mycobacterium bovis strain. For the following 40 years, BCG had been replicated, resulting in substrains ...

    • The genome of the stress-tolerant wild tomato species Solanum pennellii 

      Bolger, Anthony; Scossa, Federico; Bolger, Marie E.; Lanz, Christa; Maumus, Florian; Tohge, Takayuki; Quesneville, Hadi; Alseekh, Saleh; Sørensen, Iben; Lichtenstein, Gabriel; Fich, Eric A.; Conte, Mariana; Keller, Heike; Schneeberger, Korbinian; Schwacke, Rainer; Ofner, Itai; Vrebalov, Julia; Xu, Yimin; Osorio, Sonia; Aflitos, Saulo Alves; Schijlen, Elio; Jiménez-Goméz, José M.; Ryngajllo, Malgorzata; Kimura, Seisuke; Kumar, Ravi; Koenig, Daniel; Headland, Lauren R.; Maloof, Julin N.; Sinha, Neelima; van Ham, Roeland C. H. J.; Lankhorst, René Klein; Mao, Linyong; Vogel, Alexander; Arsova, Borjana; Panstruga, Ralph; Fei, Zhangjun; Rose, Jocelyn K. C.; Zamir, Dani; Carrari, Fernando; Giovannoni, James J.; Weigel, Detlef; Usadel, Björn; Fernie, Alisdair R. (Nature Publishing Group, 2014-09)
      Solanum pennellii is a wild tomato species endemic to Andean regions in South America, where it has evolved to thrive in arid habitats. Because of its extreme stress tolerance and unusual morphology, it is an important ...