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Relevancia clínica, diversidad y variabilidad genética de distintas especies del género Mycobacterium
(2017)Introducción: El término micobacterias no tuberculosas (MNT) incluye distintas especies ambientales capaces de enfermar humanosy/o animales incluso mediante una probable transmisión zoonótica Objetivos. Determinar: la ... -
Replication and transmission features of two experimental vaccine candidates against bovine tuberculosis subcutaneously administrated in a murine model
(Elsevier, 2022-05)Cattle vaccination is an attractive approach in compliance with control and eradication programs against Bovine Tuberculosis (bTB). Today, there is no anti bTB vaccine licensed. Two vaccine candidates, MbΔmce2 and MbΔmce2-phoP ... -
Research Note : Characterization and phylodynamic analysis of new infectious bursal disease virus variants circulating in Argentina
(Elsevier, 2024-06)Infectious Bursal Disease is a highly contagious disease that affects young chickens and leads to significant economic losses. Its causal agent is a double-stranded RNA virus that, due to its high error rate during the ... -
Respuesta inmune en terneros experimentalmente infectados con diferentes dosis de Mycobacterium bovis
(Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2011-08)La tuberculosis bovina es una enfermedad zoonótica producida por Mycobacterium bovis que afecta a animales de producción causando pérdidas económicas y representa, además, un problema para la salud pública. El conocimiento ... -
Retrotransposon and CRISPR/Cas9‑mediated knockout of NOD26 impairs the legume‑rhizobia symbiosis
(Springer, 2022-07)The multifunctional channel NOD26, identified and extensively studied (both biochemically and biophysically) in soybean, is a major protein component of the symbiosome membrane. The water and ammonia transport activities ... -
Role of PhoPR in the response to stress of Mycobacterium bovis
(Elsevier, 2021-02)PhoP is part of the two-component PhoPR system that regulates the expression of virulence genes of Mycobacteria. The goal of this work was to elucidate the role of PhoP in the mechanism that Mycobacterium bovis, the causative ... -
Rv2577 of Mycobacterium tuberculosis is a virulence factor with dual phosphatase and phosphodiesterase functions
(Frontiers Media, 2020-10)Tuberculosis, a lung disease caused by Mycobacterium tuberculosis (Mtb), is one of the ten leading causes of death worldwide affecting mainly developing countries. Mtb can persist and survive inside infected cells through ... -
Rv2617c and P36 are virulence factors of pathogenic mycobacteria involved in resistance to oxidative stress
(Taylor & Francis, 2019-12)In this study, we characterized the role of Rv2617c in the virulence of Mycobacterium tuberculosis. Rv2617c is a protein of unknown function unique to M. tuberculosis complex (MTC) and Mycobacterium leprae. In vitro, this ... -
Salicylic acid determines differential senescence produced by two turnip mosaic virus strains involving reactive oxygen species and early transcriptomic changes
(2013-12)Losses produced by virus diseases depend mostly on symptom severity. Turnip mosaic virus (TuMV) is one of the most damaging and widespread potyvirus infecting members of the family Brassicaceae, including Arabidopsis ... -
SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virus
(Frontiers Media, 2023-01)Despite recent advances in the research on oncolytic viruses (OVs), a better understanding of how to enhance their replication is key to improving their therapeutic index. Understanding viral replication is important to ... -
Secretome profile of Cellulomonas sp. B6 growing on lignocellulosic substrates
(Wiley; Society for Applied Microbiology, 2018-12)Aims: Lignocellulosic biomass deconstruction is a bottleneck for obtaining biofuels and value‐added products. Our main goal was to characterize the secretome of a novel isolate, Cellulomonas sp. B6, when grown on residual ... -
Seed dormancy QTL identification across a Sorghum bicolor segregating population
(2016)Pre-harvest sprouting (PHS) in Sorghum bicolor is one of the main constrains for its production in the central region of Argentina, as grain maturation often coincides with rainy or high environmental humidity conditions. ... -
Sequence analysis of genome segments S5 and S10 of Mal de Río Cuarto virus (Fijivirus, Reoviridae)
(Springer, 2005-06)Mal de Río Cuarto virus (MRCV) was recently described as a new species of the genus Fijivirus, family Reoviridae. The nucleotide sequence of two MRCV genome segments was determined. MRCV S5 and S10 were predicted to encode ... -
Silencing of the tomato Sugar Partitioning Affecting protein (SPA) modifies sink strength through a shift in leaf sugar metabolism
(Wiley; Society for Experimental Biology, 2014-03)Limitations in our understanding about the mechanisms that underlie source-sink assimilate partitioning are increasingly becoming a major hurdle for crop yield enhancement via metabolic engineering. By means of a ... -
Simplified methodology for large scale isolation of homozygous transgenic lines of lettuce
(2018-01)Background: Lettuce is a globally important leafy vegetable and a model plant for biotechnology due to its adaptability to tissue culture and stable genetic transformation. Lettuce is also crucial for functional genomics ... -
Single nucleotide polymorphisms may explain the contrasting phenotypes of two variants of a multidrug-resistant Mycobacterium tuberculosis strain
(2017)Globally, about 4.5% of new tuberculosis (TB) cases are multi-drug-resistant (MDR), i.e. resistant to the two most powerful first-line anti-TB drugs. Indeed, 480,000 people developed MDR-TB in 2015 and 190,000 people died ... -
Snakin-1 affects reactive oxygen species and ascorbic acid levels and hormone balance in potato
(PLOS, 2019-03-25)Snakin-1 is a member of the Solanum tuberosum Snakin/GASA family. We previously demonstrated that Snakin-1 is involved in plant defense to pathogens as well as in plant growth and development, but its mechanism of action ... -
Snakin/GASA proteins : involvement in hormone crosstalk and redox homeostasis
(Taylor & Francis, 2012)Snakin/GASA proteins are widely distributed among plant species. They are expressed in different plant organs with high tissue and temporal specificity, and their subcellular localization varies among the different members. ... -
SNP genotyping by heteroduplex analysis
(Springer, 2015-10)Heteroduplex-based genotyping methods have proven to be technologically effective and economically efficient for low- to medium-range throughput single-nucleotide polymorphism (SNP) determination. In this chapter we describe ... -
Spatial distribution of Mycobacterium bovis spoligotypes in cattle from the state of Minas Gerais, Brazil
(Springer, 2022-07)Genotyping methods have led to a better understanding of the epidemiology of Mycobacterium bovis (M. bovis) infection, and its transmission dynamics, as well as the possible phylogenetic relationships between Mycobacterium ...