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Mostrando ítems 1-8 de 8
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A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing
Cacciabue, Marco Polo; Curra, Anabella Paola; Carrillo, Elisa Cristina; Konig, Guido Alberto; Gismondi, Maria Ines (Oxford Academic Press, 2020-09)Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ... -
A computational study of the interaction of the foot and mouth disease virus VP1 with monoclonal antibodies
Marrero Diaz De Villegas, Rubén; Rodríguez Limardo, Ramiro; Carrillo, Elisa Cristina; Konig, Guido Alberto; Turjanski, Adrián G. (Elsevier, 2015-10)Foot and mouth disease is caused by a non-enveloped virus (FMDV), which disposes several antigenic sites at the surface of their capsid proteins. The most relevant and immunodominant antigenic site of FMDV (site A or AnSA) ... -
Assessing the hidden diversity underlying consensus sequences of SARS-CoV-2 using VICOS, a novel bioinformatic pipeline for identification of mixed viral populations
Goya, Stephanie; Sosa, Ezequiel Jorge; Nabaes Jodar, Mercedes Soledad; Torres, Carolina; Konig, Guido Alberto; Acuña, Dolores; Ceballos, Santiago; Distefano, Ana Julia; Dopazo, Hernán; Dus Santos, Maria Jose; Fass, Monica Irinia; Fernandez Do Porto, Darío Augusto; Fernandez, Ailen; Gallego, Fernando; Gismondi, Maria Ines; Gramundi, Ivan; Lusso, Silvina; Marti, Marcelo Adrián; Mazzeo, Melina; Mistchenko, Alicia Susana; Muñoz Hidalgo, Marianne Graziel; Natale, Mónica; Nardi, Cristina; Ousset, Julia; Peralta, Andrea Veronica; Pintos, Carolina; Puebla, Andrea Fabiana; Pianciola, Luis; Rivarola, Maximo Lisandro; Turjanski, Adrián; Valinotto, Laura; Vera, Pablo Alfredo; Zaiat, Jonathan; Zubrycki, Jeremias Enrique; Aulicino, Paula; Viegas, Mariana (Elsevier, 2023-02)Introduction: Coinfection with two SARS-CoV-2 viruses is still a very understudied phenomenon. Although next generation sequencing methods are very sensitive to detect heterogeneous viral populations in a sample, there is ... -
Differences in the virulence of two strains of Foot-and-Mouth Disease Virus Serotype A with the same spatiotemporal distribution
Garcia Nuñez, Maria Soledad; Konig, Guido Alberto; Berinstein, Analia; Carrillo, Elisa Cristina (Elsevier, 2010-01)During the 2000–2001 epidemic of Foot-and-Mouth Disease Virus (FMDV) in Argentina, two FMDV serotype A viruses were identified among others. Since different pathogenic properties between these virus strains were noticed ... -
Identification and molecular characterization of Orf virus infection in occupationally exposed women in South America
Peralta, Andrea Veronica; Flores Olivares, Carlos; Verna, Andrea Elizabeth; González Altamiranda, Erika; Odriozola, Ernesto Raul; Madariaga, Carolina; Odeon, Anselmo Carlos; Konig, Guido Alberto; Canton, German Jose (Elsevier, 2023-06)Contagious Ecthyma (CE) is a severe exanthematous dermatitis caused by the Orf virus (ORFV) that mainly affects domestic small ruminants such as sheep and goats. It is a worldwide-distributed occupational zoonosis, ... -
Phylogenetic analysis of ORF viruses from five contagious ecthyma outbreaks in Argentinian goats
Peralta, Andrea Veronica; Robles, Carlos Alejandro; Micheloud, Juan Francisco; Rossanigo, Carlos Esteban; Martinez, Agustin; Carosio, Agustin; Konig, Guido Alberto (2018-06)Orf virus (ORFV) is the etiological agent of Contagious Ecthyma (CE) disease that mainly affects sheep, goats, wild ruminants, and humans with a worldwide distribution. To date, only two strains from Argentinian sheep have ... -
Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
Brito, Barbara Patricia; Konig, Guido Alberto; Cabanne, Gustavo Sebastian; Perez Beascoechea, Claudia; Rodriguez, Luis; Perez, Andres (2016)Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After ... -
Variation in the VP1 Gene of Foot-And-Mouth Disease Virus Serotype a Associated with Epidemiological Characteristics of Outbreaks in the 2001 Epizootic in Argentina
Pérez, Andrés M.; Konig, Guido Alberto; Spath, Ernesto Juan; Thurmond, Mark C. (Sage Publishing, 2008)A mixed binomial Bayesian regression model was used to quantify the relation between nucleotide differences in the VP1 gene of Foot-and-mouth disease virus (FMDV) serotype A, and epidemiologic characteristics of the outbreaks ...