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Evidence of porcine circovirus type 2 and co-infection with ungulate protoparvovirus 1 (porcine parvovirus) in mummies and stillborn piglets in subclinically infected farm
(Elsevier, 2021-04)Porcine circovirus type 2 (PCV2) and protoparvovirus 1 (PPV) were detected as single infection (6/131) and (11/131) respectively, or co-infection (6/131) in fetuses and stillborn piglets from normal deliveries in a farm ... -
Immune cells transferred by colostrum do not influence the immune responses to foot-and-mouth disease primary vaccination
(Elsevier, 2019-09)Little is known about the influence of maternal antibodies and immune cells transferred through colostrum on the immune responses of calves to the currently used foot-and-mouth disease (FMD) vaccines. Here we evaluated the ... -
Influence of antibodies transferred by colostrum in the immune responses of calves to current foot-and-mouth disease vaccines
(2014-11-12)Immunity to currently used oil-adjuvanted inactivated vaccines against foot-and-mouth disease virus (FMDV) has been studied in detail in adult animals; however, the influence of maternally derived antibodies transferred ... -
MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1
(Wiley, 2021-03)New technologies in the field of vaccinology arise as a necessity for the treatment and control of many diseases. Whole virus inactivated vaccines and modified live virus ones used against Bovine Herpesvirus‐1 (BoHV‐1) ... -
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
(BMC, 2021-05)Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ... -
Mouse model as an efficacy test for foot‐and‐mouth disease vaccines
(Wiley, 2020-04)Protection against foot‐and‐mouth disease virus (FMDV) has been linked to the development of a humoral response. In Argentina, the official control tests for assessing the potency of FMD vaccines are protection against ... -
Novel expression of immunogenic foot-and-mouth disease virus-like particles in Nicotiana benthamiana
(2018-01)Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals and is endemic in Africa, parts of South America and southern Asia. The causative agent, FMD virus (FMDV) is a member of the genus ... -
Plant‐produced viral bovine vaccines: what happened during the last 10 years?
(Wiley, 2015-10)Vaccination has proved to be an efficient strategy to deal with viral infections in both human and animal species. However, protection of cattle against viral infections is still a major concern in veterinary science. ... -
Protection induced by a glycoprotein E-deleted bovine herpesvirus type 1 marker strain used either as an inactivated or live attenuated vaccine in cattle
(BMC, 2014-01)Background: Bovine herpesvirus type 1 (BoHV-1) is the causative agent of respiratory and genital tract infections; causing a high economic loss in all continents. Use of marker vaccines in IBR eradication programs is widely ... -
Recent advances in BLV research
(MDPI, 2015-11)Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and ... -
The MVA vector expressing the F protein of bovine respiratory syncytial virus is immunogenic in systemic and mucosal immunization routes = El vector viral MVA que expresa la proteína F del virus respiratorio sincicial bovino es inmunogénico al administrarse por vía sistémica y por mucosas
(Elsevier, 2023-12)Bovine respiratory syncytial virus (BRSV) affects both beef and dairy cattle, reaching morbidity and mortality rates of 60---80% and 20%, respectively. The aim of this study was to obtain a recombinant MVA expressing the ... -
The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine
(Plos One, 2020-05)The efficacy of foot-and-mouth disease virus (FMDV) inactivated vaccines is mainly dependent on the integrity of the whole (146S) viral particles. If the intact capsids disassemble to 12S subunits, antibodies against ... -
TLR activation, immune response and viral protection elicited in cattle by a commercial vaccine against Bovine Herpesvirus-1
(Elsevier, 2022-01)The innate and acquired immune response induced by a commercial inactivated vaccine against Bovine Herpesvirus-1 (BoHV-1) and protection conferred against the virus were analyzed in cattle. Vaccination induced high levels ... -
Transient gene expression in serum-free suspension-growing mammalian cells for the production of foot-and-mouth disease virus empty capsids
(PLOS, 2013-08-20)Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. It produces severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV). ... -
Vacuna “marcadora” contra el HVB-1
(Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2011-04)Investigadores del INTA trabajaron en el desarrollo de un producto que previene una enfermedad que provoca importantes pérdidas económicas y que permite diferenciar entre animales vacunados e infectados.