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A transcriptional analysis of cattle immune cells reveals a central role of type 1 interferon in the In vitro innate immune response against Mycobacterium bovis
(MDPI, 2023-09)Bovine tuberculosis is a chronic infectious disease primarily caused by Mycobacterium bovis, a bacterium that affects cattle and other mammals, including humans. Despite the availability of vast research about the immune ... -
An applied printing immunoassay with recombinant Nc-SAG1 for detection of antibodies to Neospora caninum in cattle
(Sage Publishing, 2011-08)Neospora caninum is a protozoan parasite that causes an important reproductive disease in cattle. Neospora caninum surface antigen 1 (Nc-SAG1) is an immunodominant candidate for the development of a diagnostic reagent for ... -
Assessment of tuberculosis biomarkers in paratuberculosis-infected cattle
(Sciendo, 2023-03)Introduction: Mycobacterium bovis and Mycobacterium avium subsp. paratuberculosis, respectively the causative agents of bovine tuberculosis (bTB) and bovine paratuberculosis (PTB), share a high number of antigenic proteins. ... -
BoLA-DRB3 exon2 polymorphisms among tuberculous cattle: Nucleotide and functional variability and their association with bovine tuberculosis pathology
(Elsevier, 2020-06)Bovine tuberculosis (bTB) is caused by Mycobacterium bovis and disseminated worldwide. In Argentina, the highest prevalence occurs in dairy areas. BoLA DRB3.2 is related to the adaptive immunity in mycobacterial infections. ... -
Clade 8 and clade 6 strains of Escherichia coli O157:H7 from cattle in Argentina have Hypervirulent-Like phenotypes
(PLOS, 2015-06-01)The hemolytic uremic syndrome (HUS) whose main causative agent is enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a disease that mainly affects children under 5 years of age. Argentina is the country with the highest ... -
Comparison of DRB3.2 alleles among false-negative and positive tuberculin skin test cattle with bovine tuberculosis
(European Society of Mycobacteriology, 2024-06)Introduction: M. bovis is worldwide distributed mainly affecting livestock. Caudal Fold-Tuberculin Skin Test (CF-TST) is the primary screening tool that detects the infection in herds. Some tuberculous animals remain ... -
Desarrollo de inmunocromatografías para el diagnóstico de leptospirosis y neosporosis bovina
(2016)Los abortos en el ganado bovino implican pérdidas económicas en la industria pecuaria; los agentes infecciosos son una de las principales causas asociadas. Entre las diversas enfermedades identificadas en nuestro país como ... -
Detection of Mycobacterium bovis in Bovine and Bubaline tissues using Nested-PCR for TbD1
(PLOS, 2014-03)In the present study, a nested-PCR system, targeting the TbD1 region, involving the performance of conventional PCR followed by real-time PCR, was developed to detect Mycobacterium bovis in bovine/bubaline tissue homogenates. ... -
Development of a Multilocus Sequence Typing scheme for the study of Anaplasma marginale population structure over space and time
(Elsevier, 2015-03)Bovine Anaplasmosis caused by Anaplasma marginale is a worldwide disease prevalent in tropical and subtropical regions where Rhipicephalus microplus is considered the most significant biological vector. Molecular markers ... -
Development of an Indirect ELISA Based on a Recombinant Chimeric Protein for the Detection of Antibodies against Bovine Babesiosis
(2018)The current method for Babesia spp. serodiagnosis based on a crude merozoite antigen is a complex and time-consuming procedure. An indirect enzyme-linked immunosorbent assay (iELISA) based on a recombinant multi-antigen ... -
Diversity of the BoLA-DRB3 gene in cattle breeds from tropical and subtropical regions of Argentina
(Springer, 2021-12)Bovine leukocyte antigens (BoLA) have been widely studied because of their primary function in the recognition of pathogens by the immune system. To date, however, the characterization of the BoLA-DRB3 gene in Latin American ... -
Does Mycobacterium bovis persist in cattle in a non-replicative latent state as Mycobacterium tuberculosis in human beings?
(Elsevier, 2020-08)Members of the Mycobacterium tuberculosis complex (MTBC) are responsible for tuberculosis in several mammals. In this complex, Mycobacterium tuberculosis and Mycobacterium bovis, which are closely related, show host ... -
Early immune innate hallmarks and microbiome changes across the gut during Escherichia coli O157: H7 infection in cattle
(SpringerNature, 2020-12)The zoonotic enterohemorrhagic Escherichia coli (EHEC) O157: H7 bacterium causes diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS) in humans. Cattle are primary reservoirs and EHEC O157: H7; the bacteria ... -
Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system
(2016-11)The recently developed engineered nucleases, such as zinc-finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated nuclease ... -
Epidemiology of Babesia, Anaplasma and Trypanosoma species using a new expanded reverse line blot hybridization assay
(2018-02)Vector-borne hemoparasitic infections are a major problem that affects livestock industries worldwide, particularly in tropical and subtropical regions. In this work, a reverse line blot (RLB) hybridization assay was ... -
ERAP1 and PDE8A are downregulated in cattle protected against bovine tuberculosis
(Karger, 2017-12)Bovine tuberculosis (bTB) is a zoonotic disease caused by Mycobacterium bovis that is responsible for significant economic losses worldwide. In spite of its relevance, the limited knowledge about the host immune responses ... -
Estrategia de inmunoprofilaxis para la prevención de la rabia paresiante utilizando un virus canarypox recombinante = Immunoprophylaxis strategy for the prevention of paralytic rabies using a recombinant canarypox virus
(Servicio Nacional de Sanidad y Calidad Agroalimentaria (SENASA), 2015-03)La rabia paresiante es una enfermedad causada por el virus rábico transmitido por el vampiro común. En el norte de nuestro país, se registran anualmente un número limitado de casos por lo que es necesaria la implementación ... -
First Genome Sequence of Leptospira interrogans Serovar Pomona, Isolated from a Bovine Abortion
(2016)Leptospirosis is a widespread zoonosis and a re-emergent disease of global distribution with major relevance in veterinary pro- duction. Here, we report the whole-genome sequence of Leptospira interrogans serovar Pomona ... -
Identification and evaluation of new Mycobacterium bovis antigens in the in vitro interferon gamma release assay for bovine tuberculosis diagnosis
(Elsevier, 2015-12)Bovine tuberculosis (bTB) is a common zoonotic disease, caused by Mycobacterium bovis (M. bovis), responsible for significant economic losses worldwide. Its diagnosis is based on the detection of cell mediated immunity ... -
Immunohistochemical detection of pro-inflammatory and anti-inflammatory cytokines in granulomas in cattle with natural Mycobacterium bovis infection
(2017)Cellular immune response was evaluated in lymph nodes and lung with different granulomatous lesions from cattle naturally infected with Mycobacterium bovis. For this purpose, we assessed pro-inflammatory and anti-inflamm ...