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Cysteine proteinase C1A paralog profiles correspond with phylogenetic lineages of pathogenic piroplasmids
(MDPI, 2018-04)Piroplasmid parasites comprising of Babesia, Theileria, and Cytauxzoon are transmitted by ticks to farm and pet animals and have a significant impact on livestock industries and animal health in tropical and subtropical ... -
Degrade to survive : the intricate world of piroplasmid proteases
(Elsevier, 2023-07)Piroplasmids of the genera Babesia, Theileria, and Cytauxzoon are tick-transmitted parasites with a high impact on animals and humans. They have complex life cycles in their definitive arthropod and intermediate vertebrate ... -
Diverse tick-borne microorganisms identified in free-living ungulates in Slovakia
(BMC, 2018-09)Background: Free-living ungulates are hosts of ixodid ticks and reservoirs of tick-borne microorganisms in central Europe and many regions around the world. Tissue samples and engorged ticks were obtained from roe deer, ... -
Identification and characterization of a Babesia bigemina thrombospondin-related superfamily member, TRAP-1 : a novel antigen containing neutralizing epitopes involved in merozoite invasion
(BioMed Central, 2020-12)Background: Thrombospondin-related anonymous protein (TRAP) has been described as a potential vaccine candidate for several diseases caused by apicomplexan parasites. However, this protein and members of this family have ... -
N-Glycosylation in piroplasmids : Diversity within simplicity
(MDPI, 2021-01)N-glycosylation has remained mostly unexplored in Piroplasmida, an order of tick-transmitted pathogens of veterinary and medical relevance. Analysis of 11 piroplasmid genomes revealed three distinct scenarios regarding ... -
Reclassification of Theileria annae as Babesia vulpes sp. nov.
(2015-04)Background: Theileria annae is a tick-transmitted small piroplasmid that infects dogs and foxes in North America and Europe. Due to disagreement on its placement in the Theileria or Babesia genera, several synonyms have ... -
The Piroplasmida Babesia, Cytauxzoon, and Theileria in farm and companion animals : species compilation, molecular phylogeny, and evolutionary insights
(Springer, 2022-05)The order Piroplasmida, including the genera Babesia, Cytauxzoon, and Theileria is often referred to as piroplasmids and comprises of dixenous hemoprotozoans transmitted by ticks to a mammalian or avian host. Although ... -
The repertoire of serine rhomboid proteases of piroplasmids of importance to animal and human health
(Elsevier, 2021-05)Babesia, Theileria and Cytauxzoon are tick-borne apicomplexan protozoans of the order Piroplasmida, notorious for the diseases they cause in livestock, pets and humans. Host cell invasion is their Achilles heel, allowing ...