• Developments in plant-based vaccines against diseases of concern in developing countries 

      Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Carrillo, Elisa Cristina; Berinstein, Analia (BENTHAM Open, 2010)
      Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, the development and implementation of new vaccines remains prohibitively expensive for middle and low income countries where ...
    • Evaluación de proteínas de una isla de patogenicidad y de envolturas bacterianas de Escherichia coli 0157:H7 como vacunas para reducir su incidencia en bovinos 

      Vilte, Daniel Alejandro (Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 2015-11)
      Escherichia coli enterohemorrágico (EHEC) es un patógeno que puede causar diarrea, colitis hemorrágica, y síndrome urémico hemolítico (SUH), una enfermedad sistémica grave que afecta principalmente a los niños. En Argentina ...
    • Human brucellosis and adverse pregnancy outcomes 

      Arenas-Gamboa, Angela M.; Rossetti, Carlos Alberto; Chaki, Sankar P.; Garcia-Gonzalez, Daniel G.; Adams, Leslie G.; Ficht, Thomas A. (Springer, 2016-12)
      Purpose of Review Brucellosis is a neglected, zoonotic disease of nearly worldwide distribution. Despite brucellosis being recognized as a reproductive disease in animals, it has been historically known as a flu-like ...
    • IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials 

      Leiva, Carlos; Gallardo, Mauro Julián; Casanova, Natalia Andrea; Terzolo, Horacio; Chacana, Pablo (Elsevier, 2020-04)
      IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its ...
    • In Silico Survey and Characterization of Babesia microti Functional and Non-Functional Proteases 

      Florin-Christensen, Monica; Wieser, Sara Nathaly; Suarez, Carlos E.; Schnittger, Leonhard (MDPI, 2021-11)
      Human babesiosis caused by the intraerythrocytic apicomplexan Babesia microti is an expanding tick-borne zoonotic disease that may cause severe symptoms and death in elderly or immunocompromised individuals. In light of ...
    • INFINITy : A fast machine learning-based application for human influenza A and B virus subtyping 

      Cacciabue, Marco Polo Domingo; Marcone, Débora Natalia (Wiley, 2023-01)
      Influenza viruses are one of the main agents causing acute respiratory infections (ARI) in humans resulting in a large amount of illness and death globally.1, 2 The influenza viruses classification is based on the nomenclature ...
    • Isolation and clinical sample typing of human leptospirosis cases in Argentina 

      Varni, Vanina Delia; Caimi, Karina Cynthia; Jacob, Paulina; Chiani, Yosena; Landolt, Noelia; Schmeling, María Fernanda; Pujato, Nazarena; Vanasco, Bibiana (2016)
      Leptospira typing is carried out using isolated strains. Because of difficulties in obtaining them, direct identification of infective Leptospira in clinical samples is a high priority.Multilocus sequence typing (MLST) ...
    • Pre-columbian mycobacterial genomes reveal seals as a source of new world human tuberculosis 

      Bos, Kirsten I.; Harkins, Kelly M.; Herbig, Alexander; Coscolla, Mireia; Weber, Nico; Comas, Iñaki; Forrest, Stephen A.; Bryant, Josephine M.; Harris, Simon R.; Schuenemann, Verena J.; Campbell, Tessa J.; Majander, Kerrtu; Wilbur, Alicia K.; Guichon, Ricardo A.; Steadman, Dawnie L. Wolfe; Cook, Della Collins; Niemann, Stefan; Behr, Marcel A.; Zumarraga, Martin Jose; Bastida, Ricardo; Huson, Daniel; Nieselt, Kay; Young, Douglas; Parkhill, Julian; Buikstra, Jane E.; Gagneux, Sebastien; Stone, Anne C.; Krause, Johannes (Springer Nature, 2014-08)
      Modern strains of Mycobacterium tuberculosis from the Americas are closely related to those from Europe, supporting the assumption that human tuberculosis was introduced post-contact1. This notion, however, is incompatible ...
    • Prevención y tratamiento de Rotavirus A mediante nanoanticuerpos VHH anti-VP6 

      Maffey, Lucia (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2017-06)
      La diarrea asociada a Rotavirus A (RVA) representa una de las principales causas de mortalidad infantil a nivel mundial. Si bien la vacunación masiva contra RVA ha logrado disminuir significativamente las muertes causadas ...
    • Study of the in vivo role of Mce2R, the transcriptional regulator of mce2 operon in Mycobacterium tuberculosis 

      Forrellad, Marina Andrea; Bianco, María Veronica; Blanco, Federico Carlos; Nuñez, Javier; Klepp, Laura Ines; Vazquez, Cristina Lourdes; Santangelo, María De La Paz; Rocha, Rosana Valeria; Soria, Marcelo; Golby, Paul; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (BMC, 2013-09)
      Background: Tuberculosis is one of the leading causes of mortality throughout the world. Mycobacterium tuberculosis, the agent of human tuberculosis, has developed strategies involving proteins and other compounds called ...