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A new gnotobiotic pig model of P[6] human rotavirus infection and disease for preclinical evaluation of rotavirus vaccines
(MDPI, 2022-12)Human rotavirus (HRV) is a leading cause of gastroenteritis in children under 5 years of age. Licensed vaccines containing G1P[8] and G1-4P[8] strains are less efficacious against newly emerging P[6] strains, indicating ... -
Controlling Rotavirus-associated diarrhea: Could single-domain antibody fragments make the difference? = Hacia el control de la diarrea por rotavirus A: ¿podrían los nanoanticuerpos VHH marcar la diferencia?
(Asociación Argentina de Microbiología, 2015-10)Group A Rotavirus (RVA) remains a leading cause of severe diarrhea and child mortality. The variable domain of camelid heavy chain antibodies (VHH) display potent antigen-binding capacity, have low production costs and are ... -
Development and evaluation of a one-step multiplex real-time TaqMan® RT-qPCR assay for the detection and genotyping of equine G3 and G14 rotaviruses in fecal samples
(BMC, 2019-04)Background: Equine rotavirus A (ERVA) is the leading cause of diarrhea in neonatal foals and has a negative impact on equine breeding enterprises worldwide. Among ERVA strains infecting foals, the genotypes G3P[12] and ... -
Development of an IgY-Based treatment to control bovine Coronavirus diarrhea in dairy calves
(MDPI, 2023-03)Bovine Coronavirus (BCoV) is a major pathogen associated with neonatal calf diarrhea. Standard practice dictates that to prevent BCoV diarrhea, dams should be immunized in the last stage of pregnancy to increase BCoV-specific ... -
Efficacy of prepartum vaccination against neonatal calf diarrhea in Nelore dams as a prevention measure
(BioMed Central, 2022-08)Background: Neonatal calf diarrhea (NCD) is the leading cause of calf morbidity and mortality in beef cattle. Cow’s vaccination in last stage of pregnancy is one of the most important measures to mitigate the risk of NCD ... -
Equine rotavirus a under the one health lens : potential impacts on public health
(MDPI, 2024-01)Group A rotaviruses are a well-known cause of viral gastroenteritis in infants and children, as well as in many mammalian species and birds, affecting them at a young age. This group of viruses has a double-stranded, ... -
Novel viruses determined using fecal virome analysis in the feces of foals with diarrea
(2016)This study aims to expand the knowledge of viral species present in feces of foals suffering diarrhea using Next Generation Sequencing. This will be useful to further explore the role of new infectious agents in this illness ... -
Passive immunity to control Bovine coronavirus diarrhea in a dairy herd in Argentina = Inmunidad pasiva en el control de la diarrea por coronavirus bovino en un rodeo lechero de Argentina
(2018)Bovine coronavirus (BCoV) is a viral enteric pathogen associated with calf diarrhea worldwide being, in Argentina, mostly detected in dairy husbandry systems. The aim of the present work was to study if maternal IgG1 ... -
Prevalence of Cryptosporidium parvum in dairy calves and GP60 subtyping of diarrheic calves in central Argentina
(Springer, 2019-07)Cryptosporidiosis of calves is caused by the enteroprotozoan Cryptosporidium spp. The disease results in intense diarrhea of calves associated with substantial economic losses in dairy farming worldwide. The aim of this ... -
Prevalence, risk factors and molecular epidemiology of neonatal cryptosporidiosis of calves : The Argentine perspective
(Elsevier, 2023-10)Cryptosporidium spp. are enteroparasitic protozoans that cause cryptosporidiosis in newborn calves. Clinical signs of the infection are diarrhoea and dehydration leading to decreased productivity and economic losses in ... -
Prevención y tratamiento de Rotavirus A mediante nanoanticuerpos VHH anti-VP6
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2017-06)La diarrea asociada a Rotavirus A (RVA) representa una de las principales causas de mortalidad infantil a nivel mundial. Si bien la vacunación masiva contra RVA ha logrado disminuir significativamente las muertes causadas ... -
Quadruplex real-time TaqMan® RT-qPCR assay for differentiation of equine group A and B rotaviruses and Identification of group A G3 and G14 genotypes
(MDPI, 2023-07)Equine rotavirus A (ERVA) is the leading cause of diarrhea in foals, with G3P[12] and G14P[12] genotypes being the most prevalent. Recently, equine G3-like RVA was recognized as an emerging infection in children, and a ... -
Síndrome diarreico en potrillos, diagnóstico y caracterización de los agentes virales involucrados
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2017-08)Las diarreas neonatales representan uno de los síndromes clínicos más relevantes y frecuentes en potrillos menores de 6 meses de edad. Rotavirus grupo A (RVA) es el principal agente viral asociado a diarreas en potrillos, ... -
Type VI secretion system in pathogenic escherichia coli: structure, role in virulence, and acquisition
(Frontiers Media, 2019-08)Bacterial pathogens utilize a myriad of mechanisms to invade mammalian hosts, damage tissue sites, and evade the immune system. One essential strategy of Gram-negative bacteria is the secretion of virulence factors through ...