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Immune cells transferred by colostrum do not influence the immune responses to foot-and-mouth disease primary vaccination
(Elsevier, 2019-09)Little is known about the influence of maternal antibodies and immune cells transferred through colostrum on the immune responses of calves to the currently used foot-and-mouth disease (FMD) vaccines. Here we evaluated the ... -
Immune Response and Partial Protection against Heterologous Foot-and-Mouth Disease Virus Induced by Dendrimer Peptides in Cattle
(2018-04)Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more effective FMD vaccines. Nevertheless, previous studies of immunization with linear peptides showed that they failed to ... -
Influence of antibodies transferred by colostrum in the immune responses of calves to current foot-and-mouth disease vaccines
(2014-11-12)Immunity to currently used oil-adjuvanted inactivated vaccines against foot-and-mouth disease virus (FMDV) has been studied in detail in adult animals; however, the influence of maternally derived antibodies transferred ... -
Inmunidad adaptativa y protectora contra el virus de la fiebre aftosa en bovinos : rol de las respuestas inmunes sistémica y de mucosas
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2018)La fiebre aftosa (FA) es una enfermedad viral infectocontagiosa de curso agudo que se caracteriza por producir lesiones vesiculares en tejidos de la mucosa oronasal (incluyendo lengua, encías y paladar), ubres, espacios ... -
Mecanismos involucrados en la duración de la respuesta inmune humoral al virus de la fiebre aftosa
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1996)La fiebre aftosa constituye un serio problema sanitario que afecta a las especies biunguladas que genera severas consecuencias económicas a nivel mundial. Las vacunas formuladas con virus inactivado como antígeno (Ag) ... -
Novel expression of immunogenic foot-and-mouth disease virus-like particles in Nicotiana benthamiana
(2018-01)Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals and is endemic in Africa, parts of South America and southern Asia. The causative agent, FMD virus (FMDV) is a member of the genus ... -
Optimized adenoviral vector that enhances the assembly of FMDV O1 virus-like particles in situ increases its potential as vaccine for serotype O viruses
(Frontiers Media, 2020-11)Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding region of foot-and-mouth disease virus (FMDV) have been proven to be effective as vaccines in relevant species ... -
Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
(2016)Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After ... -
Reduction of foot-and-mouth disease virus transmission in cattle vaccinated one or two weeks before challenge using a commercial polyvalent vaccine
(Elsevier, 2020-08)Immediate vaccination of the most susceptible and epidemiological relevant animals is a crucial part of control measures that facilitate virus elimination in case of entry of foot-and-mouth disease (FMD). The objective of ... -
Selection of highly susceptible cell lines to Foot and Mouth disease virus infection
(Scientific Research, 2013-09)Different non-established cultures were examined to find those that showed high sensitivity to Foot and Mouth Disease Virus (FMDV). Ovine kidney cultures showed high sensitivity to types A, O and C, and were suitable to ... -
Systemic antibodies administered by passive immunization prevent generalization of the infection by foot-and-mouth disease virus in cattle after oronasal challenge
(2018-05)The role of passively transferred sera in the protection against aerogenous foot-and-mouth disease (FMD) virus infection in cattle was evaluated using vaccine-induced immune serum preparations obtained at 7 and 26 days ... -
Systemic Foot-and-Mouth Disease Vaccination in Cattle Promotes Specific Antibody-Secreting Cells at the Respiratory Tract and Triggers Local Anamnestic Responses upon Aerosol Infection
(2015-09)Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting biungulate species. Commercial vaccines, formulated with inactivated FMD virus (FMDV), are regularly used worldwide to control the disease. Here, ... -
The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine
(Plos One, 2020-05)The efficacy of foot-and-mouth disease virus (FMDV) inactivated vaccines is mainly dependent on the integrity of the whole (146S) viral particles. If the intact capsids disassemble to 12S subunits, antibodies against ... -
VP1 protein of Foot-and-mouth disease virus (FMDV) impairs baculovirus surface display
(Elsevier, 2013-07)The Foot-and-mouth disease virus (FMDV) causes important economical losses in livestock farming. In order to develop a novel subunit vaccine against FMDV, we constructed recombinant baculoviruses that display the protein ...