Show simple item record

resumen

Abstract
Protein secretion plays a central role in modulating the interactions of bacteria with their environments. Bacterial ribosomes synthesize up to 8000 different proteins. Almost half of these become integrated in membranes and are secreted to the periplasm or to the external milieu. Many bacterial processes , such as DNA replication, motility, transport, antibiotic resistance, scavenging of chemicals, and pathogenesis, depend on protein secretion. Thereby, [ver mas...]
dc.contributor.authorNavarro-García, Fernando
dc.contributor.authorRuiz-Perez, Fernando
dc.contributor.authorLarzabal, Mariano
dc.contributor.authorCataldi, Angel Adrian
dc.contributor.editorTorres, Alfredo G. (editor)
dc.date.accessioned2017-08-28T16:58:47Z
dc.date.available2017-08-28T16:58:47Z
dc.date.issued2016
dc.identifier.citationNavarro-Garcia F., Ruiz-Perez F., Larzábal M., Cataldi A. (2016) Secretion Systems of Pathogenic Escherichia coli. In: Torres A. (eds) Escherichia coli in the Americas. Springer, Cham
dc.identifier.isbn978-3-319-45092-6 (Online)
dc.identifier.isbn978-3-319-45091-9 (Print)
dc.identifier.otherhttps://doi.org/10.1007/978-3-319-45092-6_10
dc.identifier.urihttp://hdl.handle.net/20.500.12123/1058
dc.identifier.urihttps://link.springer.com/chapter/10.1007%2F978-3-319-45092-6_10
dc.description.abstractProtein secretion plays a central role in modulating the interactions of bacteria with their environments. Bacterial ribosomes synthesize up to 8000 different proteins. Almost half of these become integrated in membranes and are secreted to the periplasm or to the external milieu. Many bacterial processes , such as DNA replication, motility, transport, antibiotic resistance, scavenging of chemicals, and pathogenesis, depend on protein secretion. Thereby, evolutionarily unrelated protein nanomachines have been developed, which allow exported proteins to cross the Gram-negative membranes. Bacterial proteins can be exported directly from the cytoplasm out of the cell by a one-step (cytoplasm to extracellular milieu), including the type I secretion system (T1SS), T3SS, T4SS, and T6SS, or two-step (periplasm translocation step), including the T2SS and T5SS, while the T4SS can use either the one- or two-step mechanism. The T3SS, T5SS, and T6SS are the more common secretion systems in Escherichia coli and most of the secreted substrates are virulence factors related to pathogenic E. coli . In this chapter, we will describe the main characteristic of these last three secretion systems.
dc.formatapplication/pdfeng
dc.language.isoeng
dc.publisherSpringer International Publishing
dc.rightsinfo:eu-repo/semantics/restrictedAccesseng
dc.sourceEscherichia coli in the Americas / Edited by Alfredo G. Torres. Swizerland : Springer International Publishing, p. 221-249eng
dc.subjectEscherichia Coli
dc.subjectBacteria
dc.subjectPatogenicidad
dc.subjectPathogenicityeng
dc.subjectBacteria Gram Negativa
dc.subjectGram Negative Bacteriaeng
dc.titleSecretion systems of pathogenic escherichia coli
dc.typeinfo:ar-repo/semantics/parte de libro
dc.typeinfo:eu-repo/semantics/bookParteng
dc.typeinfo:eu-repo/semantics/acceptedVersioneng
dc.description.origenInst. de Biotecnología
dc.gic152229
dc.description.filFil: Navarro-García, Fernando. Instituto Politécnico Nacional. Centro de Investigación y de Estudios Avanzados.Departamento de Biología Celular; México
dc.description.filFil: Ruiz-Perez, Fernando. University of Virginia School of Medicine. Department of Pediatrics; Estados Unidos
dc.description.filFil: Larzabal, Mariano. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina
dc.description.filFil: Cataldi, Angel Adrian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina
dc.subtypelibro


Files in this item

Thumbnail

This item appears in the following Collection(s)

common

Show simple item record