• Multiomics analyses reveal the roles of the ASR1 transcription factor in tomato fruits 

      Dominguez, Pia Guadalupe; Conti, Gabriela; Duffy, Tomas; Insani, Ester Marina; Alseekh, Saleh; Asurmendi, Sebastian; Fernie, Alisdair R.; Carrari, Fernando (Oxford University Press, 2021-09)
      The transcription factor ASR1 (ABA, STRESS, RIPENING 1) plays multiple roles in plant responses to abiotic stresses as well as being involved in the regulation of central metabolism in several plant species. However, despite ...
    • Multiple challenges in the development of commercial crops using CRISPR technology 

      Ayub, Nicolás Daniel; Soto, Gabriela Cynthia (Elsevier, 2023-10)
      The CRISPR/Cas system is a highly efficient and versatile tool for editing plant genomes, with the potential to accelerate breeding programs and improve the sustainability of food production. Nevertheless, technical ...
    • Multiple ways to evade the bacteriostatic action of glyphosate in rhizobia include the mutation of the conserved serine 90 of the nitrogenase subunit NifH to alanine 

      Liebrenz, Karen Ivana; Frare, Romina Alejandra; Gomez, Maria Cristina; Pascuan, Cecilia Gabriela; Brambilla, Silvina Maricel; Soldini, Diego Omar; Maguire, Vanina; Carrio, Alejandro Javier; Ruiz, Oscar; McCormick, Wayne; Soto, Gabriela Cynthia; Ayub, Nicolás Daniel (Elsevier, 2022-07)
      The genome resequencing of spontaneous glyphosate-resistant mutants derived from the soybean inoculant E109 allowed identifying genes most likely associated with the uptake (gltL and cya) and metabolism (zigA and betA) of ...
    • MVAΔ008 viral vector encoding the model protein OVA induces improved immune response against the heterologous antigen and equal levels of protection in a mice tumor model than the conventional MVA 

      Del Medico Zajac, Maria Paula; Molinari, Maria Paula; Gravisaco, María José; Maizon, Daniel Omar; Moron, Victor Gabriel; Gherardi, Maria Magdalena; Calamante, Gabriela (Elsevier, 2021-11)
      Modified vaccinia Ankara virus (MVA) is extensively used as a vaccine vector. We have previously observed that MVAΔ008, an MVA lacking the gene that codes for interleukin-18 binding protein, significantly increases CD8+ ...
    • Mycobacterial MCE proteins as transporters that control lipid homeostasis of the cell wall 

      Klepp, Laura Ines; Sabio Y Garcia, Julia Veronica; Bigi, Fabiana (Elsevier, 2022-01)
      Mammalian cell entry (mce) genes are not only present in genomes of pathogenic mycobacteria, including Mycobacterium tuberculosis (the causative agent of tuberculosis), but also in saprophytic and opportunistic mycobacterial ...
    • Mycobacterioses in dogs and cats from Buenos Aires, Argentina 

      Barandiaran, Soledad; Martinez Vivot, Marcela; Falzoni, Elvira; Marfil, Maria Jimena; Perez Tort, Gabriela; Rovatti, Paula; Fernandez, Mónica; Iachini, Ricardo; Satek, Fernanda; Duchene, Adriana; Zumarraga, Martin Jose (Sage Publications, 2017-09)
      Mycobacterioses can produce nonspecific clinical signs in dogs and cats that make diagnosis difficult. Furthermore, the full characterization of mycobacterial agents is not always possible or practical. We characterized ...
    • Mycobacterium avium subsp. paratuberculosis (MAP) molecular diversity in cattle, sheep, and goats from Latin America and the Caribbean: a systematic review 

      Correa-Valencia, Nathalia M.; Moyano, Roberto Damian; Hernández-Agudelo, Miguel; Fernández-Silva, Jorge A. (Springer, 2021-09)
      This study aimed to systematically collect and appraise the scientific evidence to answer the research question: What MAP genotypes have been isolated from cattle, sheep, and goats in Latin America and the Caribbean? An ...
    • Mycobacterium bovis Dmce2 double deletion mutant protects cattle against challenge with virulent M. bovis 

      Blanco, Federico Carlos; Bianco, María Veronica; Garbaccio, Sergio Gabriel; Meikle, Virginia; Gravisaco, María José; Montenegro, Valeria Noely; Alfonseca, Edgar; Singh, Mahavir G.; Barandiaran, Soledad; Canal, Ana María; Vagnoni, Lucas Emilio; Buddle, Bryce Malcom; Bigi, Fabiana; Cataldi, Angel Adrian (Elsevier, 2013-05)
      A Mycobacterium bovis strain deleted in mce2A and mce2B genes (M. bovis Δmce2) was tested as an experimental vaccine in cattle challenged with a virulent M. bovis strain. Three-and-a-half-month old calves (n = 5 to 6 per ...
    • Mycobacterium bovis ESAT-6, CFP-10 and EspC antigens show high conservation among field isolates 

      Encinas, Micaela; Marfil, Maria Jimena; Garbaccio, Sergio Gabriel; Barandiaran, Soledad; Huertas, Pablo Sebastian; Morsella, Claudia Graciela; Macias, Analía; Magnano, Gabriel; Zapata, L.; Bigi, Fabiana; Cataldi, Angel Adrian; Paolicchi, Fernando; Zumarraga, Martin Jose; Eirin, Maria Emilia (Elsevier, 2018-07)
      ESAT-6, CFP-10 and EspC are virulence factors that have been extensively assayed for bovine and human tuberculosis diagnosis due their potent T-cell inducing activities. While polymorphisms of ESAT-6 and CFP-10 were analyzed, ...
    • Mycobacterium bovis infection in a horse with granulomatous enterocolitis 

      Sarradell, Javier E.; Alvarez, Julio; Biscia, Mariana; Zumarraga, Martin Jose; Wunschmann, Arno; Armien, Aníbal G.; Perez, Andrés M. (Sage Publications, 2015-03)
      A 2-year-old dappled Percheron horse had a wasting condition that did not respond to antibiotic treatments and ultimately resulted in death. Thickening of the wall of the large colon and enlargement of the mesenteric lymph ...
    • Mycobacterium bovis requires P27 (LprG) to arrest phagosome maturation and replicate within bovine macrophages 

      Vazquez, Cristina Lourdes; Bianco, María Veronica; Blanco, Federico Carlos; Forrellad, Marina Andrea; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (2017-03)
      Mycobacterium bovis causes tuberculosis in a wide variety of mammals, with strong tropism for cattle and eventually humans. P27, also called LprG, is among the proteins involved in the mechanisms of the virulence and ...
    • Mycobacterium intracellulare infection in a capybara (Hydrochoerus hydrochaeris) 

      Pezzone, Natalia; Eberhardt, Ayelén; Fernandez, Analía; Garbaccio, Sergio Gabriel; Zumarraga, Martin Jose; Gioffre, Andrea; Magni, Carolina; Beldomenico, Pablo Martín; Marini, M. Rocío; Canal, Ana María (American Association of Zoo Veterinarians, 2013-12)
      This report describes the first case of Mycobacterium intracellulare infection with typical granulomatous lesions of mycobacteriosis in a capybara (Hydrochoerus hydrochaeris). The individual was a captive-bred young female, ...
    • Mycobacterium tuberculosis infection in a free‑ranging urban dog from Argentina 

      Marfil, Maria Jimena; Barandiaran, Soledad; Zumarraga, Martin Jose; Germani, Ludmila; Faccini, Tamara; Linares, Marcelo; Capra, Silvana; Gramajo, Laura; Martinez Vivot, Marcela; Falzoni, Elvira (Springer, 2022-02)
      Mycobacterium bovis and Mycobacterium avium are the most important Mycobacteria isolated from diseased dogs, but Mycobacterium tuberculosis can be isolated as well, especially when close contact with humans exists. Free ...
    • Mycoparasitic interaction between Trichoderma afroharzianum strain Th2RI99 and Rhizoctonia solani = Interacción micoparasítica entre Trichoderma afroharzianum cepa Th2RI99 y Rhizoctonia solani 

      Melignani, Eliana; Martin, Mara Edith; Mema, Vanesa Yamila; Taibo, Catalina Beatriz; Sabio Y Garcia, Julia Veronica; Barrera, Viviana Andrea (Elsevier, 2023)
      The behavior of Trichoderma afroharzianum strain Th2RI99 confronted to Rhizoctonia solani AG4-HG II in dual culture was observed under light (LM) and scanning electron microscope (SEM). There is evidence of mycoparasitism ...
    • Natural occurring epialleles determine vitamin E accumulation in tomato fruits 

      Quadrana, Leandro Daniel; Almeida de Souza, Juliana Beatriz; Asis, Ramón; Duffy, Tomas; Dominguez, Pia Guadalupe; Bermudez Salazar, Luisa; Conti, Gabriela; Silva, Junia V. Corrêa da; Peralta, Iris Edith; Colot, Vincent; Asurmendi, Sebastian; Fernie, Alisdair R.; Rossi, Magdalena; Carrari, Fernando Oscar (2014-07)
      Vitamin E (VTE) content is a low heritability nutritional trait for which the genetic determinants are poorly understood. Here, we focus on a previously detected major tomato VTE quantitative trait loci (QTL; mQTL9-2-6) ...
    • Negative modulation of the GABAAρ1 receptor function by histamine 

      Beltrán González, Andrea N.; López Pazos, Manuel I.; Del Vas, Mariana; Calvo, Daniel Juan (Elsevier, 2023-09)
      Besides its function as a local mediator of the immune response, histamine can play a role as a neurotransmitter and neuromodulator. Histamine actions are classically mediated through four different G protein-coupled ...
    • Neotropical termite microbiomes as sources of novel plant cell wall degrading enzymes 

      Romero Victorica, Matias; Soria, Marcelo Abel; Batista-García, Ramón Alberto; Ceja-Navarro, Javier A.; Vikram, Surendra; Ortiz, Maximiliano; Ontañon, Ornella; Ghio, Silvina; Martínez-Ávila, Liliana; Quintero García, Omar Jasiel; Etcheverry, Clara; Campos, Eleonora; Cowan, Donald; Arneodo Larochette, Joel Demian; Talia, Paola Mónica (Springer Nature, 2020-03-02)
      In this study, we used shotgun metagenomic sequencing to characterise the microbial metabolic potential for lignocellulose transformation in the gut of two colonies of Argentine higher termite species with different ...
    • Network and biosignature analysis for the integration of transcriptomic and metabolomic data to characterize leaf senescence process in sunflower 

      Moschen, Sebastian Nicolas; Higgins, Janet; Di Rienzo, Julio A.; Heinz, Ruth Amelia; Paniego, Norma Beatriz; Fernandez, Paula Del Carmen (2016)
      In recent years, high throughput technologies have led to an increase of datasets from omics disciplines allowing the understanding of the complex regulatory networks associated with biological processes. Leaf senescence ...
    • Neuronal network analyses reveal novel associations between volatile organic compounds and sensory properties of tomato fruits 

      Cortina, Pablo Ramiro; Santiago, Ana N.; Sance, María M.; Peralta, Iris Edith; Carrari, Fernando; Asis, Ramón (Springer, 2018-05)
      Introduction The process of tomato (Solanum lycopersicum) breeding has affected negatively the fruit organoleptic properties and this is evident when comparing modern cultivars with heirloom varieties. Flavor of tomato ...
    • New validated eucalyptus SSR markers located in candidate genes involved in growth and plant development 

      Acuña, Cintia Vanesa; Rivas, Juan Gabriel; Aguirre, Natalia Cristina; Villalba, Pamela Victoria; Martinez, Maria Carolina; Garcia, Martin Nahuel; Hopp, Horacio Esteban; Marcucci Poltri, Susana Noemi (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (España), 2020)
      Aim of study: To validate and characterize new microsatellites or Simple Sequence Repeats (SSR) markers, located within genomic transcribed sequences related to growth and plant developmental traits, in Eucalyptus ...