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Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles
(Elsevier, 2019-12)Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic ... -
Efficient method for targeted gene disruption by homologous recombination in Mycobacterium avium subspecie paratuberculosis
(Elsevier, 2020-09)Targeted gene disruption by homologous recombination, has been widely used in mycobacterium species to understand the genetic basis of virulence and persistence in the host and to develop efficacious potential live vaccines. ... -
Mapping causal mutations by exome sequencing in a wheat TILLING population: a tall mutant case study
(Springer, 2018-04)Forward genetic screens of induced mutant plant populations are powerful tools to identify genes underlying phenotypes of interest. Using traditional techniques, mapping causative mutations from forward screens is a lengthy, ... -
Multiple ways to evade the bacteriostatic action of glyphosate in rhizobia include the mutation of the conserved serine 90 of the nitrogenase subunit NifH to alanine
(Elsevier, 2022-07)The genome resequencing of spontaneous glyphosate-resistant mutants derived from the soybean inoculant E109 allowed identifying genes most likely associated with the uptake (gltL and cya) and metabolism (zigA and betA) of ... -
Surveillance and characterization of drug‑resistant mycobacterium tuberculosis isolated in a reference hospital from Argentina during 8 years’ period
(Wolters Kluwer, 2019-09)Background: Argentina is considered a country with a middle tuberculosis (TB) incidence. However, according to the last national epidemiological report released in 2018, since 2013, the trends are steadily increasing. The ... -
The Gln15Arg mutation in the transcriptional factor PALM1 produces multifoliate alfalfa
(Springer, 2022-12)The CRISPR/Cas9 system has proven to be highly valuable for genome editing in several important crops, including the allogamous tetraploid cultivated alfalfa (Medicago sativa). However, the fact that most of the beneficial ...