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Mostrando ítems 1-12 de 12
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Comparative analysis of the midgut microbiota of two natural tick vectors of Rickettsia rickettsii
(Elsevier, 2020-05)Although the ticks Amblyomma sculptum and Amblyomma aureolatum are important vectors of Rickettsia rickettsii, causative agent of the life-threatening Rocky Mountain spotted fever, A. aureolatum is considerably more ... -
Deletion of A44L, A46R and C12L vaccinia virus genes from the MVA genome improved the vector immunogenicity by modifying the innate immune response generating enhanced and optimized specific T-Cell responses
(2016-05)MVA is an attenuated vector that still retains immunomodulatory genes. We have previously reported its optimization after deleting the C12L gene, coding for the IL-18 binding-protein. Here, we analyzed the immunogenicity ... -
Desarrollo de candidatos vacunales contra Babesia bovis basados en vectores virales y proteínas recombinantes
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2016-09)La babesiosis bovina es una enfermedad parasitaria trasmitida por garrapatas y causada por los protozooarios intraeritrocíticos Babesia bovis y B. bigemina. Esta infección provoca importantes pérdidas económicas en varias ... -
Development of a novel set of Gateway-compatible vectors for live imaging in insect cells
(The Royal Entomological Society, 2011-10)Insect genomics is a growing area of research. To exploit fully the genomic data that are being generated, high-throughput systems for the functional characterization of insect proteins and their interactomes are required. ... -
Estudio de la interacción hospedante-patógeno entre el Mal de Río Cuarto virus (MRCV) y el delfácido transmisor Delphacodes kuscheli
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2011)El virus del Mal de Río Cuarto (MRCV, Reoviridae, Fijivirus) causa la principal enfermedad que afecta al maíz en la Argentina. Su genoma consiste en diez segmentos de ARN de doble cadena (S1 a S10) que codifican para un ... -
Minimizing the time and cost of production of transgenic alfalfa libraries using the highly efficient completely sequenced vector pPZP200BAR
(2016)Alfalfa is the most important forage legume worldwide. However, similar to other minor forage crops, it is usually harvested along with weeds, which decrease its nutrient quality and thus reduce its high value in the ... -
MVAΔ008 viral vector encoding the model protein OVA induces improved immune response against the heterologous antigen and equal levels of protection in a mice tumor model than the conventional MVA
(Elsevier, 2021-11)Modified vaccinia Ankara virus (MVA) is extensively used as a vaccine vector. We have previously observed that MVAΔ008, an MVA lacking the gene that codes for interleukin-18 binding protein, significantly increases CD8+ ... -
Nuevas estrategias para la transformación y expresión de genes de interés en girasol
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2011-09)El girasol es una especie de la familia Asteraceae (Compositae) de gran importancia económica, considerada hasta hace una década recalcitrante al cultivo in vitro y la transformación genética. En un trabajo previo (Radonic, ... -
pBAR–H3.2, a native-optimized binary vector to bypass transgene silencing in alfalfa
(Springer, 2020-03)Alfalfa is the main forage worldwide due to its high biomass production, excellent nutritional qualities and adaptation to a wide range of environments (Singer et al. 2018). Besides, due to its ability to grow without ... -
Rats as sources of multidrug-resistant Enterobacteriaceae in animal production environments
(Wiley, 2023-07)Rattus norvegicus and Rattus rattus are commensal pest rodents, considered reservoirs and vectors of zoonotic pathogens. In livestock farms, the wide use of antimicrobials and their release into the environment lead to ... -
Transovarial transmission of anaplasma marginale in Rhipicephalus (Boophilus) microplus ticks results in a bottleneck for strain diversity
(MDPI, 2023-08)Anaplasma marginale is an obligate intraerythrocytic bacterium of bovines, responsible for large economic losses worldwide. It is mainly transmitted by Rhipicephalus (Boophilus) microplus ticks and, despite mounting evidence ... -
Uso de Brucella abortus como vector para la expresión de antígenos heterólogos
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2012-03)La brucelosis es una zoonosis bacteriana causada por especies del género Brucella. B. abortus S19 es la cepa vacunal en uso en nuestro país. Debido a su capacidad para despertar una respuesta inmune celular y humoral, B. ...