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    • A fungal protease named AsES triggers antiviral immune responses and effectively restricts virus infection in arabidopsis and Nicotiana benthamiana plants 

      Caro, Maria Del Pilar; Venturuzzi, Andrea Laura; Moschen, Sebastian Nicolas; Salazar, Sergio Miguel; Díaz Ricci, Juan Carlos; Asurmendi, Sebastian (Oxford University Press, 2022-04)
      Background and Aims: Plants have evolved complex mechanisms to fight against pathogens. Among these mechanisms, pattern-triggered immunity (PTI) relies on the recognition of conserved microbe- or pathogen-associated molecular ...
    • Age‑performance and intensity of grooming behavior toward Varroa destructor in resistant and susceptible Apis mellifera colonies 

      Russo, Romina Maria; Landi, Lucas; Muntaabski, Irina; Liendo, María Clara; Pietronave, Hernan Pablo; Merke, Julieta; Rodriguez, Graciela Adriana; Palacio, María Alejandra; Basilio, Alicia Mabel; Lanzavecchia, Silvia Beatriz; Scannapieco, Alejandra Carla (Springer, 2022-10)
      Grooming behavior confers resistance to honey bees against Varroa destructor, being of interest to social immunity studies and breeding programs. The objective of this study was to characterize at the individual level the ...
    • An oral salmonella-based vaccine inhibits liver metastases by promoting tumor-specific T-cell-mediated immunity in celiac and portal lymph nodes : a preclinical study 

      Vendrell, Alejandrina; Mongini, Claudia; Gravisaco, Marí­a José; Canellada, Andrea; Tesone, Agustina Inés; Goin, Juan Carlos; Waldner, Claudia Inés (2016)
      Primary tumor excision is one of the most widely used therapies of cancer. However, the risk of metastases development still exists following tumor resection. The liver is a common site of metastatic disease for numerous ...
    • Association of TNF rs668920841 and INRA111 polymorphisms with caprine brucellosis: A case-control study of candidate genes involved in innate immunity 

      Hasenauer, Flavia Carolina; Rossi, Ursula; Caffaro, María Eugenia; Raschia, Maria Agustina; Maurizio, Estefanía; Poli, Mario Andres; Rossetti, Carlos Alberto (Elsevier, 2020-11)
      Caprine brucellosis is an infectious, contagious zoonotic disease caused by Brucella melitensis. Multiple factors, including host genetics, can influence the outcome of the exposure to Brucella; and it is expected that ...
    • Bovine colostral cells : the often forgotten component of colostrum 

      Gonzalez, Diego; Dus Santos, Maria Jose (American Veterinary Medical Association, 2017-05)
      Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally ...
    • Co-inoculation of baculovirus and FMDV vaccine in mice, elicits very early protection against foot and mouth disease virus without interfering with long lasting immunity 

      Quattrocchi, Valeria; Molinari, Maria Paula; Langellotti, Cecilia Ana; Gnazzo, Victoria; Taboga, Oscar Alberto; Zamorano, Patricia Ines (Elsevier, 2013-05-31)
      Baculoviruses (Bvs) potentiate the immune response against soluble antigens. We investigated whether Bv could be used as immunoactivator in foot-and-mouth disease (FMD) vaccines using the BALB/c mouse model. Mice were ...
    • FMD empty capsids combined with the immunostant particle adjuvant -ISPA or ISA206 induce protective immunity against foot and mouth disease virus 

      Bidart, Juan Esteban; Mignaqui, Ana Clara; Kornuta, Claudia Alejandra; Lupi, Giuliana; Gammella, Mariela; Soria, Ivana; Galarza, Roxana Ivon; Ferella, Alejandra; Cardillo, Sabrina Beatriz; Langellotti, Cecilia Ana; Quattrocchi, Valeria; Durocher, Yves; Wigdorovitz, Andres; Marcipar, Ivan; Zamorano, Patricia Ines (Elsevier, 2021-05)
      Foot and Mouth Disease Virus (FMDV) causes economy losses and is controlled by vaccination in many countries. Vaccine formulations based on empty capsids or Virus-Like Particles (VLPs) have the advantage of avoiding the ...
    • Fusion of foreign T-cell epitopes and addition of TLR agonists enhance immunity against Neospora caninum profilin in cattle 

      Mansilla, Florencia Celeste; Quintana, Maria Eugenia; Cardoso, Nancy; Capozzo, Alejandra (2016)
      We demonstrated recently that immunization with recombinant Neospora caninum profilin (rNcPRO) induces limited protection and a regulatory T-cell response in mice. The aim of this study was to evaluate the immune response ...
    • Individual precocity, temporal persistence, and task-specialization of hygienic bees from selected colonies of apis mellifera 

      Scannapieco, Alejandra Carla; Lanzavecchia, Silvia Beatriz; Parreño, María Alejandra; Liendo, María Clara; Cladera, Jorge Luis; Spivak, Marla; Palacio, Marí­a Alejandra (2016)
      Hygienic behaviour is a complex trait that gives Apis mellifera L. resistance against brood diseases. Variability in the expression of hygienic behaviour is evidenced at the colonylevel and is explained by the proportion ...
    • Inmunidad adaptativa y protectora contra el virus de la fiebre aftosa en bovinos : rol de las respuestas inmunes sistémica y de mucosas 

      Barrionuevo, Florencia Mariel (Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2018)
      La fiebre aftosa (FA) es una enfermedad viral infectocontagiosa de curso agudo que se caracteriza por producir lesiones vesiculares en tejidos de la mucosa oronasal (incluyendo lengua, encías y paladar), ubres, espacios ...
    • Modulation of host plant immunity by Tobamovirus proteins 

      Conti, Gabriela; Rodriguez, Maria Cecilia; Venturuzzi, Andrea Laura; Asurmendi, Sebastian (2017-03)
      To establish successful infection, plant viruses produce profound alterations of host physiology, disturbing unrelated endogenous processes and contributing to the development of disease. In tobamoviruses, emerging evidence ...
    • Pseudomonas fluorescens Pf-5 genome-wide mutant screen for resistance to the antimicrobial peptide alfalfa snakin-1 

      Ayub, Nicolás Daniel; Fox, Ana Romina; Garcia, Araceli Nora; Mozzicafreddo, Matteo; Cuccioloni, Massimiliano; Angeletti, Mauro; Pagano, Elba Maria; Soto, Gabriela Cynthia (Oxford University Press, 2015-01)
      Snakin-1, a peptide produced by higher plants, has broad-spectrum antibiotic activity, inhibiting organisms ranging from Bacteria to Eukaryotes. However, the mode of action against target organisms is poorly understood. ...
    • The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine 

      Mansilla, Florencia Celeste; Turco, Cecilia Soledad; Miraglia, Maria Cruz; Bessone, Fernando Aníbal; Franco, Raul Enrique; Perez Filgueira, Daniel Mariano; Sala, Juan Manuel; Capozzo, Alejandra (Plos One, 2020-05)
      The efficacy of foot-and-mouth disease virus (FMDV) inactivated vaccines is mainly dependent on the integrity of the whole (146S) viral particles. If the intact capsids disassemble to 12S subunits, antibodies against ...