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Metabolic profile of mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis

Resumen
Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins in the pathogen Mycobacterium tuberculosis but little is known about these proteins in Mycobacterium smegmatis, a soil dweller species. Objective To investigate the role of Mce proteins in M. [ver mas...]
Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins in the pathogen Mycobacterium tuberculosis but little is known about these proteins in Mycobacterium smegmatis, a soil dweller species. Objective To investigate the role of Mce proteins in M. smegmatis. [Cerrar]
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Autor
Santangelo, María De La Paz;   Heuberger, Adam;   Blanco, Federico Carlos;   Forrellad, Marina Andrea;   Taibo, Catalina Beatriz;   Klepp, Laura Ines;   Sabio y Garcia, Julia Veronica;   Nikel, Pablo I.;   Jackson, Mary;   Bigi, Fabiana;  
Fuente
Metabolomics 12 (6) : 97. (June 2016)
Fecha
2016
ISSN
1573-3882 (Print)
1573-3890 (Online)
URI
http://hdl.handle.net/20.500.12123/1193
DOI
https://doi.org/10.1007/s11306-016-1035-4
Formato
pdf
Tipo de documento
article
Palabras Claves
Genética; Genetics; Metabolismo; Metabolism; Mycobacterium; Homeostasis; Perfil Metabólico; Mycobacterium Smegmatis;
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Excepto donde se diga explicitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
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