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Abstract
The aim of this study was to evaluate the effect of Dexamethasone (DXM) on clinical parameters, absolute and differential leukocyte count, specific IgG titers, IFN-γ production and parasitemia in beef calves seropositive to Neospora caninum. Fifteen calves were assigned to four experimental groups as follow: group A: 4 sero- positive calves treated with DXM; group B: 4 seropositive calves without DXM; group C: 3 seronegative calves treated with DXM, and [ver mas...]
dc.contributor.authorIdarraga Bedoya, Samuel
dc.contributor.authorArmendano, Joaquín Ignacio
dc.contributor.authorGual, Ignacio
dc.contributor.authorHecker, Yanina
dc.contributor.authorLeunda, Maria Rosa
dc.contributor.authorPereyra, Susana Beatriz
dc.contributor.authorVerna, Andrea Elizabeth
dc.contributor.authorCampero, Carlos Manuel
dc.contributor.authorOdeon, Anselmo Carlos
dc.contributor.authorMoore, Prando Dadin
dc.date.accessioned2020-06-23T16:28:47Z
dc.date.available2020-06-23T16:28:47Z
dc.date.issued2020-03-09
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/20.500.12123/7460
dc.identifier.urihttp://kjclinicalmedicine.org/files/KJCM-1004.pdf
dc.description.abstractThe aim of this study was to evaluate the effect of Dexamethasone (DXM) on clinical parameters, absolute and differential leukocyte count, specific IgG titers, IFN-γ production and parasitemia in beef calves seropositive to Neospora caninum. Fifteen calves were assigned to four experimental groups as follow: group A: 4 sero- positive calves treated with DXM; group B: 4 seropositive calves without DXM; group C: 3 seronegative calves treated with DXM, and group D: 4 seronegative calves without DXM treatment. The absolute leukocyte count was higher in both groups A and C in the 3rd day after the first dose of DXM mainly due to a significant neutrophilia (p<0.05). No changes in the total specific IgG titers or ratios between their subisotypes or antibodies against NcGRA7 and NcSAG4 antigens were observed in calves from group A com- pared with those in group B (p>0.05). Similarly, IFN-γ levels did not change among experimental groups (p>0.05). DNA was de- tected in calves from groups A and B at 7 Days Post Administra- tion (dpa) and from group A at 14 dpa. Even when DXM adminis- tration induced hemotological parameter changes, no reactivation of Neospora-infection was observed according to specific IgG titers and presence of the parasite on leukocytes in naturally seropositive beef male calves.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)es_AR
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.sourceKorean Journal of Clinical Medicine 1 (1) : 1-6 (2020)es_AR
dc.subjectTerneroes_AR
dc.subjectCalveseng
dc.subjectDexametasonaes_AR
dc.subjectDexamethasoneeng
dc.subjectNeospora Caninumes_AR
dc.subjectInmunologíaes_AR
dc.subjectImmunologyeng
dc.subjectSerologíaes_AR
dc.subjectSerologyeng
dc.subjectEnfermedades de los Animaleses_AR
dc.subjectAnimal Diseaseseng
dc.titleEffect of dexamethasone in Neospora Caninum seropositive calveses_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.description.filFil: Idarraga-Bedoya Samuel. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.es_AR
dc.description.filFil: Armendano Joaquin Ignacio. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.es_AR
dc.description.filFil: Gual, Ignacio. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina.es_AR
dc.description.filFil: Hecker Yanina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.es_AR
dc.description.filFil: Leunda María Rosa. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.es_AR
dc.description.filFil: Pereyra Susana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.es_AR
dc.description.filFil: Verna Andrea Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.es_AR
dc.description.filFil: Campero Carlos Manuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.es_AR
dc.description.filFil: Odeon Anselmo Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina.es_AR
dc.description.filFil: Moore Dadin Prando. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.es_AR
dc.subtypecientifico


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