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Distinctive features of bovine alphaherpesvirus types 1 and 5 and the virus-host interactions that might influence clinical outcomes

Abstract
Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alpha-herpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the [ver mas...]
Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alpha-herpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation with respiratory and neurological syndromes, which characterize the infections by each virus, respectively. [Cerrar]
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Author
Marin, Maia Solange;   Burucua, María Mercedes;   Resentti, Daniel;   Rosales, Juan José;   Odeon, Anselmo Carlos;   Pérez, Sandra;  
Fuente
Archives of Virology 165 : 285–301 (2020)
Date
2019-12-16
Editorial
Springer
ISSN
0304-8608
1432-8798
URI
http://hdl.handle.net/20.500.12123/7358
https://link.springer.com/article/10.1007/s00705-019-04494-5
DOI
https://doi.org/10.1007/s00705-019-04494-5
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Tipo de documento
artículo
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Excepto donde se diga explicitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
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