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Abstract
Aspergillus flavus is a filamentous, saprophytic fungus, whose colonization occurs mainly in cereal grains and oilseeds once arvested. Under certain conditions, it could produce mycotoxins called aflatoxins, known as powerful human liver carcinogens. The aim of the present study was to describe the antifungal activity of extracts of Peltophorum dubium, a species from northern Argentina (Oriental Chaco), against A. flavus. The antifungal activities of di [ver mas...]
dc.contributor.authorDi Ciaccio, Lucía Soledad
dc.contributor.authorCatalano, Alejandro V.
dc.contributor.authorLópez, Paula G.
dc.contributor.authorRojas, Dante Emanuel
dc.contributor.authorCristos, Diego Sebastian
dc.contributor.authorFortunato, Renee Hersilia
dc.contributor.authorSalvat, Adriana Elisabeth
dc.date.accessioned2020-05-21T11:37:33Z
dc.date.available2020-05-21T11:37:33Z
dc.date.issued2020-04-02
dc.identifier.issn2223-7747
dc.identifier.otherhttps://doi.org/10.3390/plants9040438
dc.identifier.urihttp://hdl.handle.net/20.500.12123/7283
dc.identifier.urihttps://www.mdpi.com/2223-747/9/4/438
dc.description.abstractAspergillus flavus is a filamentous, saprophytic fungus, whose colonization occurs mainly in cereal grains and oilseeds once arvested. Under certain conditions, it could produce mycotoxins called aflatoxins, known as powerful human liver carcinogens. The aim of the present study was to describe the antifungal activity of extracts of Peltophorum dubium, a species from northern Argentina (Oriental Chaco), against A. flavus. The antifungal activities of di erent collection sites are reported. The extracts exhibited a minimum inhibitory concentration of 125 g/mL, and the di erences between the treatments and the inoculum control were 11 mm of P. dubium A and 10 mm of P. dubium F in colony growth. Moreover, hyphae treated with the extracts stained blue with Evans blue showed alterations in the membrane and/or cell wall, allowing the dye income. Bio-guided fractionation, High Performance Liquid Chromatography diode array ultraviolet/visible (HPLC UV/VIS DAD), and Ultra-High Performance Liquid Chromatography Electrospray Ionization Mass Spectrometry (UPLC ESI-MS) analyses were conducted to characterize the extracts and their active fractions. The HPLC UV/VIS DAD analysis allowed the determination of the presence of flavonoids (flavonols and flavones), coumarins, terpenes, and steroids. UPLC ESI/MS analysis of active fractions revealed the presence of Kaempferol, Apigenin, Naringenin, Chrysin and aidzein.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherMDPI
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.sourcePlants 9 (4) : 438 (2020)es_AR
dc.subjectAspergillus flavuses_AR
dc.subjectFlavonoidseng
dc.subjectFlavonoideses_AR
dc.subject.otherPlant Bioactivityeng
dc.subject.otherBioactividad de la Plantaes_AR
dc.subject.otherEvans Blueeng
dc.subject.otherEvans Azules_AR
dc.subject.otherActive Extract Characterizationeng
dc.subject.otherCaracterización de Extracto Activoes_AR
dc.titleIn vitro antifungal activity of Peltophorum dubium (Spreg.) Taub. extracts against Aspergillus flavus.es_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.description.filFil: Di Ciaccio, Lucí­a Soledad. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentinaes_AR
dc.description.filFil: Catalano, Alejandra V. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Farmacognosia; Argentinaes_AR
dc.description.filFil: López, Paula G. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Farmacognosia; Argentinaes_AR
dc.description.filFil: Rojas, Dante. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; Argentinaes_AR
dc.description.filFil: Fortunato, Renee Hersilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentinaes_AR
dc.description.filFil: Salvat, Adriana Elisabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentinaes_AR
dc.description.filFil: Cristos, Diego Sebastián. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; Argentina
dc.subtypecientifico


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