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Abstract
IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may [ver mas...]
dc.contributor.authorLeiva, Carlos
dc.contributor.authorGallardo, Mauro Julián
dc.contributor.authorCasanova, Natalia Andrea
dc.contributor.authorTerzolo, Horacio
dc.contributor.authorChacana, Pablo
dc.date.accessioned2020-02-11T11:10:19Z
dc.date.available2020-02-11T11:10:19Z
dc.date.issued2020-04
dc.identifier.issn1567-5769
dc.identifier.otherhttps://doi.org/10.1016/j.intimp.2020.106269
dc.identifier.urihttp://hdl.handle.net/20.500.12123/6713
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1567576919323677
dc.description.abstractIgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its cost-effective extraction, the minimization of animal harm and distress, and its reduced reactivity with mammalian factors. Many research groups have demonstrated that IgY is active against several pathogens or conditions, a fact that may support the design of novel, safe and effective health products. This review provides a comprehensive analysis of IgY-based biologicals for human medicine, including patent applications and clinical trials during the period 2010–2018, and addresses how IgY-technology can lead to innovation in the production of biologicals for the treatment and prophylaxis of a wide range of infectious and non-communicable diseases.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherElsevieres_AR
dc.rightsinfo:eu-repo/semantics/restrictedAccesses_AR
dc.sourceInternational Immunopharmacology 81 : 106269 (Abril 2020)es_AR
dc.subjectAntibodieseng
dc.subjectAnticuerposes_AR
dc.subjectEgg Yolkeng
dc.subjectYema de Huevoes_AR
dc.subjectTherapyeng
dc.subjectTerapiaes_AR
dc.subjectPatentseng
dc.subjectPatenteses_AR
dc.subjectClinical Trialseng
dc.subjectEnsayos Clínicoses_AR
dc.subjectMedical Scienceseng
dc.subjectCiencias Médicases_AR
dc.subjectHuman Diseaseseng
dc.subjectEnfermedades Humanases_AR
dc.subject.otherIgY Antibodyeng
dc.subject.otherAnticuerpo IgYes_AR
dc.titleIgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trialses_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.description.origenInstituto de Patobiologíaes_AR
dc.description.filFil: Leiva, Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Gallardo, Mauro Julián. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Casanova, Natalia Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Terzolo, Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Chacana, Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.subtypecientifico


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