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Abstract
The aim of this study was to evaluate delayed type hypersensitivity (DTH) induced by the intradermal inoculation of a Neospora caninum tachyzoite soluble lysate in cattle previously exposed with the protozoa. Four experimental groups were selected according to the prior exposure to N. caninum antigen. All cows were intradermally injected with a N. caninum tachyzoite soluble lysate and skinfold thickness growth at the inoculation sites was measured at 0, [ver mas...]
dc.contributor.authorFiorani, Franco
dc.contributor.authorArmendano, Joaquín Ignacio
dc.contributor.authorHecker, Yanina Paola
dc.contributor.authorAraoz, Virgina
dc.contributor.authorCanton, German Jose
dc.contributor.authorLeunda, Maria Rosa
dc.contributor.authorPereyra, Susana Beatriz
dc.contributor.authorCorva, Pablo Marcelo
dc.contributor.authorOdeon, Anselmo Carlos
dc.contributor.authorMoore, Prando Dadin
dc.date.accessioned2019-04-01T13:09:53Z
dc.date.available2019-04-01T13:09:53Z
dc.date.issued2019-01
dc.identifier.issn0165-2427
dc.identifier.issn1873-2534
dc.identifier.otherhttps://doi.org/10.1016/j.vetimm.2018.11.011
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0165242718302150
dc.identifier.urihttp://hdl.handle.net/20.500.12123/4795
dc.description.abstractThe aim of this study was to evaluate delayed type hypersensitivity (DTH) induced by the intradermal inoculation of a Neospora caninum tachyzoite soluble lysate in cattle previously exposed with the protozoa. Four experimental groups were selected according to the prior exposure to N. caninum antigen. All cows were intradermally injected with a N. caninum tachyzoite soluble lysate and skinfold thickness growth at the inoculation sites was measured at 0, 24, 48, 72 and 96 h post inoculation (hpi). Additionally, specific antibodies and IFN-γ production were assessed. Cows experimentally infected with live N. caninum tachyzoites and cows naturally exposed to N. caninum developed skin reactions compatible with DTH between 24 and 96 hpi (p < 0.05). Moreover, cows inoculated with an experimental N. caninum vaccine and cows without evidence of exposure to N. caninum did not show a significant increase in skin thickness (p > 0.05). Furthermore, serological status of the animals was not modified due to the intradermal inoculation. The highest IFN-γ production was observed at 15 days after intradermal inoculation (p < 0.05). Therefore, these results suggest that cattle previously exposed to N. caninum develop a reaction compatible with DTH which could be useful as in vivo cell mediated immunity parameter for assessed bovine neosporosis.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherElsevieres_AR
dc.rightsinfo:eu-repo/semantics/restrictedAccesses_AR
dc.sourceVeterinary Immunology and Immunopathology 207 : 31-35 (January 2019)es_AR
dc.subjectGanado Bovinoes_AR
dc.subjectCattleeng
dc.subjectNeospora Caninumes_AR
dc.subjectHipersensibilidad Retardadaes_AR
dc.subjectDelayed Hypersensitivityeng
dc.subjectInoculaciónes_AR
dc.subjectInoculationeng
dc.subjectEnfermedades Parasitariases_AR
dc.subjectParasitoseseng
dc.titleDelayed type hypersensitivity induced by intradermal inoculation of a Neospora caninum tachyzoite antigen in previously exposed cattlees_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.description.origenEEA Balcarcees_AR
dc.description.filFil: Fiorani, Franco. Consejo Nacional de Investigaciones Científicas y Técnicas;, Argentinaes_AR
dc.description.filFil: Armendano, Joaquín Ignacio. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentinaes_AR
dc.description.filFil: Hecker, Yanina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Araoz, Virginia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Canton, German Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Leunda, María Rosa. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Pereyra, Susana Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Corva, Pablo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentinaes_AR
dc.description.filFil: Odeon, Anselmo Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Moore, Prando Dadin. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentinaes_AR
dc.subtypecientifico


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