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Abstract
Although Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging [ver mas...]
dc.contributor.authorJalovecka, Marie
dc.contributor.authorSojka, Daniel
dc.contributor.authorAscencio, Mariano E.
dc.contributor.authorSchnittger, Leonhard
dc.date.accessioned2019-03-26T15:34:34Z
dc.date.available2019-03-26T15:34:34Z
dc.date.issued2019-02-04
dc.identifier.issn1471-4922
dc.identifier.otherhttps://doi.org/10.1016/j.pt.2019.01.007
dc.identifier.urihttp://hdl.handle.net/20.500.12123/4744
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1471492219300200?via%3Dihub
dc.description.abstractAlthough Babesia represents an important worldwide veterinary threat and an emerging risk to humans, this parasite has been poorly studied as compared to Plasmodium, its malaria-causing relative. In fact, Babesia employs highly specific survival strategies during its intraerythrocytic development and its intricate journey through the tick vector. This review introduces a substantially extended molecular phylogeny of the order Piroplasmida, challenging previous taxonomic classifications. The intriguing developmental proficiencies of Babesia are highlighted and compared with those of other haemoparasitic Apicomplexa. Molecular mechanisms associated with distinctive events in the Babesia life cycle are emphasized as potential targets for the development of Babesia-specific treatments.eng
dc.formatapplication/pdfeng
dc.language.isoeng
dc.publisherElsevier
dc.rightsinfo:eu-repo/semantics/restrictedAccesseng
dc.sourceTrends in parasitology. (4 February 2019)eng
dc.subjectBabesiaes_AR
dc.subjectCiclo Vitales_AR
dc.subjectLife Cycleeng
dc.subjectPhylogenyeng
dc.subjectFilogeniaes_AR
dc.subjectBiologyeng
dc.subjectBiologíaes_AR
dc.subjectMetastigmataes_AR
dc.subjectMolecular Biologyeng
dc.subjectBiología Moleculares_AR
dc.titleBabesia life cycle – When phylogeny meets biologyeng
dc.typeinfo:ar-repo/semantics/reseña artículoes_AR
dc.typeinfo:eu-repo/semantics/revieweng
dc.typeinfo:eu-repo/semantics/publishedVersioneng
dc.description.origenInstituto de Patobiologíaes_AR
dc.description.filFil: Jalovecka, Marie. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checa. University of South Bohemia. Faculty of Science; República Checaes_AR
dc.description.filFil: Sojka, Daniel. Czech Academy of Sciences. Institute of Parasitology, Biology Centre; República Checaes_AR
dc.description.filFil: Ascencio, Mariano E. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Schnittger, Leonhard. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.subtypecientifico


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