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Abstract
Neospora caninum infection in cattle stimulates host immune responses, which may be responsible for placental damage leading to abortion. Susceptibility of water buffaloes (Bubalus bubalis) to neosporosis is not well understood, although vertical transmission and fetal death have been documented. The aim of this study was to characterize the immune response in the placentome of water buffalo following experimental infection in early gestation with the [ver mas...]
dc.contributor.authorCanton, German Jose
dc.contributor.authorKonrad, Jose Luis
dc.contributor.authorMoore, Prando Dadin
dc.contributor.authorCaspe, Sergio Gaston
dc.contributor.authorPalarea-Albaladejo, Javier
dc.contributor.authorCampero, Carlos Manuel
dc.contributor.authorChianini, Francesca
dc.date.accessioned2019-03-08T13:56:25Z
dc.date.available2019-03-08T13:56:25Z
dc.date.issued2014-05
dc.identifier.issn0021-9975
dc.identifier.otherhttps://doi.org/10.1016/j.jcpa.2013.12.003
dc.identifier.urihttp://hdl.handle.net/20.500.12123/4559
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0021997513003836
dc.description.abstractNeospora caninum infection in cattle stimulates host immune responses, which may be responsible for placental damage leading to abortion. Susceptibility of water buffaloes (Bubalus bubalis) to neosporosis is not well understood, although vertical transmission and fetal death have been documented. The aim of this study was to characterize the immune response in the placentome of water buffalo following experimental infection in early gestation with the Nc-1 strain of N. caninum. Placentomes were examined by immunohistochemistry using antibodies specific for T-cell subsets, natural killer cells and CD79αcy cells. Placental inflammation was characterized by the infiltration of CD3+ and CD4+ T cells and T cells expressing the γδ T-cell receptor. The distribution of these cellular subsets in buffalo placentomes was similar to that previously described in cattle infected with N. caninum in early gestation, but the lesions were milder, which may explain the lower number of abortions observed in this species after infection.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherElsevieres_AR
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceJournal of Comparative Pathology 150 (4) : 463-468 (May 2014)es_AR
dc.subjectNeospora caninumes_AR
dc.subjectRespuesta Inmunológicaes_AR
dc.subjectImmune Responseeng
dc.subjectBúfalo de Aguaes_AR
dc.subjectWater Buffaloeseng
dc.subjectGestaciónes_AR
dc.subjectPregnancyeng
dc.subjectInmunidades_AR
dc.subjectImmunityeng
dc.titleCharacterization of Immune Cell Infiltration in the Placentome of Water Buffaloes (Bubalus bubalis) Infected with Neospora caninum During Pregnancyes_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/acceptedVersiones_AR
dc.rights.licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.description.origenEEA Balcarcees_AR
dc.description.filFil: Canton, German Jose. Moredun Research Institute; Reino Unido. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Konrad, Jose Luis. Universidad Nacional del Nordeste. Facultad de Veterinaria; Argentinaes_AR
dc.description.filFil: Moore, Prando Dadin. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Caspe, Sergio Gaston. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mercedes; Argentinaes_AR
dc.description.filFil: Palarea-Albaladejo, Javier. Biomathematics & Statistics Scotland; Reino Unidoes_AR
dc.description.filFil: Campero, Carlos Manuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Chianini, Francesca. Moredun Research Institute; Reino Unidoes_AR
dc.subtypecientifico


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