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Resumen
Infection with Neospora caninum stimulates host cell-mediated immune responses, which may be responsible for placental damage leading to bovine abortion. The aim of this study was to compare immune responses in the bovine placenta, following experimental infection in different stages of pregnancy. Placentomes were examined by immunohistochemistry and inflammation in early gestation was generally moderate to severe, particularly in the placentas carrying [ver mas...]
dc.contributor.authorCanton, German Jose
dc.contributor.authorKatzer, Frank
dc.contributor.authorMaley, Stephen W.
dc.contributor.authorBartley, Paul M.
dc.contributor.authorBenavides-Silván, Julio
dc.contributor.authorPalarea-Albaladejo, Javier
dc.contributor.authorPang, Yvonne
dc.contributor.authorSmith, Sionagh
dc.contributor.authorRocchi, Mara
dc.contributor.authorBuxton, David
dc.contributor.authorInnes, Elisabeth A.
dc.contributor.authorChianini, Francesca
dc.date.accessioned2018-12-03T17:46:10Z
dc.date.available2018-12-03T17:46:10Z
dc.date.issued2014-01
dc.identifier.issn0928-4249
dc.identifier.issn1297-9716
dc.identifier.otherhttps://doi.org/10.1186/1297-9716-45-11
dc.identifier.urihttps://veterinaryresearch.biomedcentral.com/articles/10.1186/1297-9716-45-11
dc.identifier.urihttp://hdl.handle.net/20.500.12123/4002
dc.description.abstractInfection with Neospora caninum stimulates host cell-mediated immune responses, which may be responsible for placental damage leading to bovine abortion. The aim of this study was to compare immune responses in the bovine placenta, following experimental infection in different stages of pregnancy. Placentomes were examined by immunohistochemistry and inflammation in early gestation was generally moderate to severe, particularly in the placentas carrying non-viable foetuses, whereas it was milder in later stages, mainly characterised by the presence of CD3+, CD4+ and γδ T-cells. This distinctive cellular immune response may explain the milder clinical outcome observed when animals are infected in later gestation.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherBMCes_AR
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceVeterinary Research 45 : 11 (2014)es_AR
dc.subjectNeospora caninumes_AR
dc.subjectGanado Bovinoes_AR
dc.subjectCattleeng
dc.subjectEnfermedades de los Animaleses_AR
dc.subjectAnimal Diseaseseng
dc.subjectPlacentaes_AR
dc.subjectInflamaciónes_AR
dc.subjectInflammationeng
dc.subjectGestaciónes_AR
dc.subjectPregnancyeng
dc.titleInflammatory infiltration into placentas of Neospora caninum challenged cattle correlates with clinical outcome of pregnancyes_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.rights.licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.description.origenEEA Balcarcees_AR
dc.description.filFil: Canton, German Jose. Moredun Research Institute; Reino Unido. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentinaes_AR
dc.description.filFil: Katzer, Frank. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Maley, Stephen W. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Bartley, Paul M. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Benavides-Silván, Julio. Moredun Research Institute; Reino Unido. Consejo Superior de Investigaciones Científicas. Instituto de Ganadería de Montaña; Españaes_AR
dc.description.filFil: Palarea-Albaladejo, Javier. Biomathematics & Statistics Scotland; Reino Unidoes_AR
dc.description.filFil: Pang, Yvonne. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Smith, Sionagh. University of Edinburgh. Royal (Dick) School of Veterinary Studies and Roslin Institute; Reino Unidoes_AR
dc.description.filFil: Rocchi, Mara. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Buxton, David. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Innes, Elisabeth A. Moredun Research Institute; Reino Unidoes_AR
dc.description.filFil: Chianini, Francesca. Moredun Research Institute; Reino Unidoes_AR
dc.subtypecientifico


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