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    • A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos 

      Canizo, Jésica Romina; Ynsaurralde Rivolta, Amanda Eugenia; Vazquez Echegaray, Camila; Suvá, Mariana; Alberio, Virgilia; Aller Atucha, Juan Florencio; Guberman, Alejandra; Salamone, Daniel; Alberio, Ricardo; Alberio, Ramiro (BioMed Central, 2019-07-04)
      Background: The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been ...