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Mostrando ítems 1-2 de 2
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A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos
Canizo, Jésica Romina; Ynsaurralde Rivolta, Amanda Eugenia; Vazquez Echegaray, Camila; Suvá, Mariana; Alberio, Virgilia; Aller Atucha, Juan Florencio; Guberman, Alejandra; Salamone, Daniel Felipe; Alberio, Ricardo; Alberio, Ramiro (BioMed Central, 2019-07-04)Background: The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been ... -
Exogenous human OKSM factors maintain pluripotency gene expression of bovine and porcine iPS-like cells obtained with STEMCCA delivery system
Canizo, Jésica Romina; Vazquez Echegaray, Camila; Klisch, Doris; Aller Atucha, Juan Florencio; Paz, Dante; Alberio, Ricardo; Alberio, Ramiro; Guberman, Alejandra (BioMedCentral, 2018-07-27)OBJECTIVES: The use of induced pluripotent stem (iPS) cells as an alternative to embryonic stem cells to produce transgenic animals requires the development of a biotechnological platform for their generation. In this ...