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Resumen
Although bovine herpesvirus type 4 (BoHV-4) is primarily associated with reproductive disorders of cattle, it can produce a variety of clinical signs. To determine the distribution, the presence and type of microscopic lesions caused by BoHV-4 strains of different genotypes an in vivo model, calves were infected with three phylogenetically different Argentinean BoHV-4 strains. Samples from nasal and ocular secretions, peripheral blood leukocytes, tissues [ver mas...]
dc.contributor.authorMorán, Pedro Edgardo
dc.contributor.authorPérez, Sandra Elizabet
dc.contributor.authorGarcía, Jorge Pablo
dc.contributor.authorCastro, Alejandra Nelly Cristina
dc.contributor.authorSppeter, Lucas Maximiliano
dc.contributor.authorOdeon, Anselmo Carlos
dc.contributor.authorVerna, Andrea Elizabeth
dc.date.accessioned2018-03-15T11:26:57Z
dc.date.available2018-03-15T11:26:57Z
dc.date.issued2017
dc.identifier.issn1519-2563 (Print)
dc.identifier.issn2357-9323 (Online)
dc.identifier.otherhttp://dx.doi.org/10.17525/vrrjournal.v22i1.330
dc.identifier.urihttp://hdl.handle.net/20.500.12123/2023
dc.identifier.urihttp://157.86.113.86/index.php/vrrjournal/article/view/330/303
dc.description.abstractAlthough bovine herpesvirus type 4 (BoHV-4) is primarily associated with reproductive disorders of cattle, it can produce a variety of clinical signs. To determine the distribution, the presence and type of microscopic lesions caused by BoHV-4 strains of different genotypes an in vivo model, calves were infected with three phylogenetically different Argentinean BoHV-4 strains. Samples from nasal and ocular secretions, peripheral blood leukocytes, tissues and serum were analyzed. BoHV-4 was isolated from nasal and ocular secretions at 7 and 14 days post-inoculation (dpi). Viral DNA was detected by nested PCR in peripheral blood leukocytes at 14 and 21 dpi for two out of three strains and in tissues, such as nervous system, trachea, pulmonary and retropharyngeal lymph nodes, spleen and kidney, at 21 dpi. Antibody levels detected by viral seroneutralization test were mostly low and varied widely for the different strains. The tissue distribution of the BoHV-4 strains and the variations observed in the levels of neutralizing antibodies indicate that certain differences can be established among the patterns of biological behavior of each strain. This is an initial step to get insight into the biological characteristics of Argentinean BoHV-4 isolates. However, further evaluation involving a higher number of inoculated animals will be required to be conclusive on this aspect.eng
dc.formatapplication/pdf
dc.language.isoeng
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceVirus Reviews & Research 22 : 12-19 (2017)
dc.subjectTernero
dc.subjectVirus de los Animales
dc.subjectAnimal Viruseseng
dc.subjectHerpes Virus Bovino
dc.subjectBovine Herpesviruseng
dc.subjectDistribución en Tejidos
dc.subjectTissue Distributioneng
dc.subjectGanado Bovino
dc.subjectCattleeng
dc.subject.otherArgentina
dc.titleTissular distribution of argentinean strains of bovine herpesvirus type 4 (BoHV-4) in experimentally-infected calves
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.rights.licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.description.origenEEA Balcarce
dc.gic155586
dc.description.filFil: Morán, Pedro Edgardo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
dc.description.filFil: Perez, Sandra Elizabet. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tandil. Centro de Investigación Veterinaria de Tandil; Argentina
dc.description.filFil: García, Jorge Pablo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
dc.description.filFil: Castro, Alejandra Nelly Cristina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina
dc.description.filFil: Sppeter, Lucas Maximiliano. Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT); Argentina
dc.description.filFil: Odeon, Anselmo Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina
dc.description.filFil: Verna, Andrea Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.subtypecientifico


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