Temas 

Temas

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    • Benznidazole/Poloxamer 407 Solid Dispersion as a New Strategy to Improve the Treatment of Experimental Trypanosoma cruzi Infection 

      Davies, Carolina; Simonazzi, Analía; Micheloud, Juan Francisco; Ragone, Paula Gabriela; Cid, Alicia Graciela; Sánchez Negrette, Olga; Bermúdez, José María; Parada, Luis Antonio (American Society of Parasitologists, 2020-05-04)
      Benznidazole and nifurtimox are the only drugs specifically approved for the treatment of Chagas disease. Both compounds are given orally in tablets, but occasionally are ineffective and cause adverse effects. Benznidazole, ...

    • Development and assessment of a new cage‐like particle adjuvant 

      Bertona, Daiana; Pujato, Nazarena; Bontempi, Iván; González, Verónica Doris Guadalupe; Cabrera, Gabriel Gustavo; Gugliotta, Luis Marcelino; Hozbor, Daniela Flavia; Nicastro, Alcides; Calvinho, Luis Fernando; Marcipar, Iván Sergio (2017-10)
      Objectives: To obtain and assess stable cage‐like particles with low surface charge density, which can be prepared using a standardized, economic and scalable method. Methods: To form these nanoparticles, the lipid ...