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Mostrando ítems 1-3 de 3

    • A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos 

      Canizo, Jésica Romina; Ynsaurralde Rivolta, Amanda Eugenia; Vazquez Echegaray, Camila; Suvá, Mariana; Alberio, Virgilia; Aller Atucha, Juan Florencio; Guberman, Alejandra; Salamone, Daniel Felipe; Alberio, Ricardo; Alberio, Ramiro (BioMed Central, 2019-07-04)
      Background: The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been ...

    • Exogenous human OKSM factors maintain pluripotency gene expression of bovine and porcine iPS-like cells obtained with STEMCCA delivery system 

      Canizo, Jésica Romina; Vazquez Echegaray, Camila; Klisch, Doris; Aller Atucha, Juan Florencio; Paz, Dante; Alberio, Ricardo; Alberio, Ramiro; Guberman, Alejandra (BioMedCentral, 2018-07-27)
      OBJECTIVES: The use of induced pluripotent stem (iPS) cells as an alternative to embryonic stem cells to produce transgenic animals requires the development of a biotechnological platform for their generation. In this ...

    • In vitro developmental competence of bovine demi-embryos generated by blastomere separation and blastocyst bisection 

      Ynsaurralde Rivolta, Amanda Eugenia; Gambini, Andrés; Alberio, Virgilia; Savy, Virginia; Ratner, Laura Daniela; Guberman, Alejandra; Vazquez Echegaray, Camila; Gismondi, Maria Ines; Curra, Anabella Paola; Bevacqua, Romina Jimena; Salamone, Daniel Felipe (Wiley, 2024-06)
      The efficiency of bovine in vitro embryo production can be significantly improved by splitting embryos at different stages. However, the blastocyst quality of in vitro-produced demi-embryos remains unexplored. The objective ...